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Ferrous Sulfate?

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Denis Marier

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Jan 5, 2003, 4:21:00 PM1/5/03
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I have a prescription for Apo-Ferrous Sulfate 300MG.
I have noticed that some 300MG tablets produced by different manufacturers
vary in size.
I wonder what makes some manufacturer increase the sizes of tablets for the
same strength?


N-H-P

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Jan 5, 2003, 7:00:35 PM1/5/03
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Once upon a time, our fellow Denis Marier
rambled on about "Ferrous Sulfate?."
Our champion De-Medicalizing in sci.med.nutrition retorts, thusly ...

>I have a prescription for Apo-Ferrous Sulfate 300MG.
>I have noticed that some 300MG tablets produced by different manufacturers
>vary in size.

Wow! 300 mg of Apo-Ferrous Sulfate.

Us natural people wouldn't take more than 30 mg of Ferrous Sulfate in
a single pill. You are liable to get very constipated.

The final determination of what is best for the patient is both the
right and responsibility of the individual patient.
--
John Gohde,
Patient Empowerment Advocate
http://home.naturalhealthperspective.com/empowerment.html
Email: N...@NaturalHealthPerspective.com
www.NaturalHealthPerspective.com - Pioneering De-Medicalization by
handing back the power to the people, encouraging self care and
autonomy, and resisting the categorization of life's problems as
medical.

Denis Marier

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Jan 5, 2003, 8:17:27 PM1/5/03
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Thanks for your reply John. I do not take Ferrous Sulfate 300MG by choice.
After several lab tests it was determined that my red cells were at a low
level. This in turn caused pernicious anemia along with other system
anomalies. It all started after two 6 hours major surgeries. The
anesthesiologist informed me before putting to sleep that the special dosage
required for the surgery might lower the red cells level which it did well.
Under normal circumstances the iron required for the human body to function
adequately is found in your daily diet. That is if you eat well and know the
structure, chemistry, insecticide and fungicide of your food regiment
amongst other things.

"N-H-P" <N-...@hotmail.com> wrote in message
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Sandy

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Jan 7, 2003, 7:36:26 AM1/7/03
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On Mon, 06 Jan 2003 01:17:27 GMT, "Denis Marier" <mar...@nbnet.nb.ca>
wrote:

>Thanks for your reply John. I do not take Ferrous Sulfate 300MG by choice.
>After several lab tests it was determined that my red cells were at a low
>level. This in turn caused pernicious anemia along with other system
>anomalies. It all started after two 6 hours major surgeries. The
>anesthesiologist informed me before putting to sleep that the special dosage
>required for the surgery might lower the red cells level which it did well.
>Under normal circumstances the iron required for the human body to function
>adequately is found in your daily diet.

Don't take much notice of this idiot. He dribble off at the mouth like
a pavlovian dog when anyone posts on this group.

>That is if you eat well and know the
>structure, chemistry, insecticide and fungicide of your food regiment
>amongst other things.

The first condition is fine, but the rest is irrelevant nonsense.


>"N-H-P" <N-...@hotmail.com> wrote in message
>news:eovg1vssh1ftqul0p...@4ax.com...
>> Once upon a time, our fellow Denis Marier
>> rambled on about "Ferrous Sulfate?."
>> Our champion De-Medicalizing in sci.med.nutrition retorts, thusly ...
>>
>> >I have a prescription for Apo-Ferrous Sulfate 300MG.
>> >I have noticed that some 300MG tablets produced by different
>manufacturers
>> >vary in size.
>>
>> Wow! 300 mg of Apo-Ferrous Sulfate.
>>
>> Us natural people wouldn't take more than 30 mg of Ferrous Sulfate in
>> a single pill. You are liable to get very constipated.
>>
>> The final determination of what is best for the patient is both the
>> right and responsibility of the individual patient.
>> --
>> John Gohde,

Sandy

Sandy

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Jan 7, 2003, 7:37:11 AM1/7/03
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On Mon, 06 Jan 2003 00:00:35 GMT, N-H-P <N-...@hotmail.com> wrote:

>Once upon a time, our fellow Denis Marier
> rambled on about "Ferrous Sulfate?."
>Our champion De-Medicalizing in sci.med.nutrition retorts, thusly ...
>
>>I have a prescription for Apo-Ferrous Sulfate 300MG.
>>I have noticed that some 300MG tablets produced by different manufacturers
>>vary in size.
>
>Wow! 300 mg of Apo-Ferrous Sulfate.
>
>Us natural people wouldn't take more than 30 mg of Ferrous Sulfate in
>a single pill. You are liable to get very constipated.

Why very constipated, exactly?

Listen up, Stupid, I suggest you think before you dribble off at the
mouth with utter rubbish. The usual ferrous sufate tablet contains 105
mg of iron, or 350 mg of ferrous sulfate.
The usual adult dose is 100 mg if iron per day


Sandy

Sandy

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Jan 7, 2003, 7:39:18 AM1/7/03
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On Sun, 05 Jan 2003 21:21:00 GMT, "Denis Marier" <mar...@nbnet.nb.ca>
wrote:

>I have a prescription for Apo-Ferrous Sulfate 300MG.

Fillers, binders. Ferrous sulfate is very dangerous if swallowed by
children. It is very acidic and will damage their gut wall. (And their
livers if not treated immediately) It used to be up amongst the most
common poisoning of children, eating mum's attractive, pale green iron
tabs. Maybe some of the fillers are designed to minimise this danger.
Ask a pharmacist.


Sandy

Denis Marier

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Jan 7, 2003, 8:53:18 AM1/7/03
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Hi Sandy,

Today pharmacists worked at filling prescriptions. When I asked the
pharmacist she replies to contact the fabricator, which I am awaiting
answers.
I also contacted other pharmacists and the reply I got was that they were
not trained as pharmacologist ( uses,effects and mode of action of drug and
food). When checking the DIN (drug identification numbers) I soon learned
that the only data required by the government is to list the chemistry. In
this case the chemistry read: Iron preparation. This does not tell you what
are in the iron composition.
It would appear that the filling used could be lactose? Why lactose, I do
not know. Your rationalization about young children inadvertently taken an
iron pill could validate the extra filling with lactose. No one would make
an official statement to that effect. What if one is allergic to lactose.


"Sandy" <3@2.1> wrote in message
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Sandy

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Jan 7, 2003, 9:38:13 AM1/7/03
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On Tue, 07 Jan 2003 13:53:18 GMT, "Denis Marier" <mar...@nbnet.nb.ca>
wrote:

>Hi Sandy,


>
>Today pharmacists worked at filling prescriptions. When I asked the
>pharmacist she replies to contact the fabricator, which I am awaiting
>answers.
>I also contacted other pharmacists and the reply I got was that they were
>not trained as pharmacologist ( uses,effects and mode of action of drug and
>food). When checking the DIN (drug identification numbers) I soon learned
>that the only data required by the government is to list the chemistry. In
>this case the chemistry read: Iron preparation. This does not tell you what
>are in the iron composition.
>It would appear that the filling used could be lactose? Why lactose, I do
>not know. Your rationalization about young children inadvertently taken an
>iron pill could validate the extra filling with lactose. No one would make
>an official statement to that effect. What if one is allergic to lactose.

Do you mean lactose intolerant? You can't be allergic to a sugar, only
proteins I believe. The small amount of lactose will be unnoticeable.
It will not protect from the damage of ferrous sulfate. I should have
specified a pharmacist from a hospital, or a teaching institution.
Retailers generally don't go into formulation.


Sandy

Dr. S. Geek, Ph.D.

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Jan 7, 2003, 5:17:20 PM1/7/03
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DATE: Tue, 07 Jan 2003 12:36:26 GMT
TO: Sandy
FROM: Dr. S. Geek, Ph.D.
SUBJECT: "Re: Ferrous Sulfate?."
NG: sci.med.nutrition
==========

>Don't take much notice of this idiot. He dribble off at the mouth like
>a pavlovian dog when anyone posts on this group.

Sandy, must have walked into a wall?

She/He always likes to talk about her/him ...self.

Sandy is from down under where they like to do everything backwards
and contrary.
--
Another we know next to nothing about nutrition
moment brought to you by Dr. S. Geek, Ph.D.

Science is all about knowing less and less
about more and more.

Dr. S. Geek, Ph.D.

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Jan 7, 2003, 5:20:31 PM1/7/03
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DATE: Tue, 07 Jan 2003 12:37:11 GMT

TO: Sandy
FROM: Dr. S. Geek, Ph.D.
SUBJECT: "Re: Ferrous Sulfate?."
NG: sci.med.nutrition
==========

>Listen up, Stupid, I suggest you think before you dribble off at the


>mouth with utter rubbish. The usual ferrous sufate tablet contains 105
>mg of iron, or 350 mg of ferrous sulfate.
>The usual adult dose is 100 mg if iron per day

Listen up, Stupid!

30 mg of ferrous sulfate means precisely 30 mg of ferrous sulfate.

Just thought that you might want to know. :)

You can stick your 300 mg pills up your arse, Sandy.

Sandy

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Jan 8, 2003, 2:26:06 AM1/8/03
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On Tue, 07 Jan 2003 22:20:31 GMT, "Dr. S. Geek, Ph.D."
<SG...@hotmail.com> wrote:

>DATE: Tue, 07 Jan 2003 12:37:11 GMT
>TO: Sandy
>FROM: Dr. S. Geek, Ph.D.
>SUBJECT: "Re: Ferrous Sulfate?."
>NG: sci.med.nutrition
>==========
>
>>Listen up, Stupid, I suggest you think before you dribble off at the
>>mouth with utter rubbish. The usual ferrous sufate tablet contains 105
>>mg of iron, or 350 mg of ferrous sulfate.
>>The usual adult dose is 100 mg if iron per day
>
>Listen up, Stupid!
>
>30 mg of ferrous sulfate means precisely 30 mg of ferrous sulfate.

And that is less than a third of the usual daily therapeutic dose.
What precisely is your point?

>Just thought that you might want to know. :)
>
>You can stick your 300 mg pills up your arse, Sandy.

I don't need iron therapy. But if I did, I would take the recommended
350 mg per day (po). Why can't you admit that you shot your mouth off
and then put you foot in it? Too immature?

Sandy

Sandy

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Jan 8, 2003, 2:29:28 AM1/8/03
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On Tue, 07 Jan 2003 22:17:20 GMT, "Dr. S. Geek, Ph.D."
<SG...@hotmail.com> wrote:

>DATE: Tue, 07 Jan 2003 12:36:26 GMT
>TO: Sandy
>FROM: Dr. S. Geek, Ph.D.
>SUBJECT: "Re: Ferrous Sulfate?."
>NG: sci.med.nutrition
>==========
>

>>Don't take much notice of this idiot. He dribbles off at the mouth like
>>a Pavlovian dog when anyone posts on this group.


>
>Sandy, must have walked into a wall?
>
>She/He always likes to talk about her/him ...self.
>
>Sandy is from down under where they like to do everything backwards
>and contrary.

Is that the best you can manage?
A bit juvenile, no?

Sandy

Alf Christophersen

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Jan 11, 2003, 10:15:24 AM1/11/03
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On Mon, 06 Jan 2003 00:00:35 GMT, N-H-P <N-...@hotmail.com> wrote:

>Us natural people wouldn't take more than 30 mg of Ferrous Sulfate in
>a single pill. You are liable to get very constipated.

Perhaps this could be of interest?

Eur J Haematol 2002 Oct;69(4):236-42 Related Articles, Links


Possible ameliorative effect of taurine in the treatment of
iron-deficiency anaemia in female university students of Gaza,
Palestine.

Sirdah MM, El-Agouza IM, Abu Shahla AN.

Biology Department, Faculty of Science, Al Azhar University, PO Box
1277 Gaza, Gaza Strip, Palestine. msi...@hotmail.com

The aim of the study was to evaluate the haematological effects of
adding the antioxidant taurine to iron sulfate in the treatment of
iron-deficiency anaemia (IDA). A sample of 730 students from Al-Azhar
University, Gaza, in Palestine underwent screening with complete blood
counts and serum samples. In subjects with microcytosis/hypochromasia,
Alpha2 delta2 (HbA2) and serum concentrations of iron, total iron
binding capacity (TIBC), ferritin and taurine were determined. Samples
from 17 normocytic, normochromic, and non-anaemic subjects were used
as baseline controls. At base-line, 81 of the 730 subjects (11.1%) had
microcytosis/hypochromasia, 26 (3.6%) were diagnosed as
beta-thalassemia carriers, none of which was iron deficient. Four
subjects had microcytosis of unknown cause. Fifty-one subjects (all
females) had iron-deficiency anaemia and were included in the
therapeutic study, which lasted for 20 wk. They were matched for Hb
into pairs and were treated with oral iron (325 mg of slow-release
iron sulfate). In addition, they were, in a double-blind procedure,
randomised to additional oral taurine (1000 mg d(-1) at a cost
comparable to that of adding ascorbic acid) or placebo. Mean S-taurine
was significantly lower in the IDA subjects than in the controls.
After 20 wk of iron supplementation, both the taurine and placebo
group significantly improved their Hb concentrations and normalised
the markers of iron deficiency. Apart from the expected, albeit in
this study mild side-effects of oral iron, no significant side-effects
were noted. In the taurine group, there was a statistically
significant additive positive change from the baseline values on Hb
(2.67 +/- 1.24 g dL(-1)), red blood cell (RBC) count [(0.57 +/- 0.25)
x 1012 L(-1)] and serum ferritin (30.33 +/- 17.99 microg L(-1)) as
compared to placebo group values, which were 1.80 +/- 1.10 g dL-1,
(0.39 +/- 0.36) x 1012 L(-1), and 20.11 +/- 7.34 microg L(-1),
respectively. Oral taurine appears to increase the effectiveness of
oral iron in the treatment of IDA, and has no significant
side-effects. This merits further cost-benefit and clinical analyses.

Alf Christophersen

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Jan 11, 2003, 10:18:48 AM1/11/03
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On Tue, 07 Jan 2003 14:38:13 GMT, Sandy <3@2.1> wrote:

>Do you mean lactose intolerant? You can't be allergic to a sugar, only
>proteins I believe. The small amount of lactose will be unnoticeable.

If lactose glycate an apoproteine, the holoproteine can be allergenic,
if the product is unknown to the immune system, but the apoproteine
being a normal protein.

Denis Marier

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Jan 11, 2003, 2:08:45 PM1/11/03
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Do you mean lactose intolerant?
The small amount of lactose will be unnoticeable.
Yes. this may be right. Taking one 300mg tablet of ferrous sulfate loaded
with lactose as a filler will not affect an individual who is lactose
intolerant. One of my friend who is lactose intolerant confirmed it.
However, taking two ferrous sulfate tablets each day of the year may not be
tolerated as one tablet each week. The thinks that intrigues me is why load
the tablet with lactose filling.

"Alf Christophersen" <alf.chris...@basalmed.uio.no> wrote in message
news:mbd02vcpj3j505548...@4ax.com...

Sangroper

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Jan 15, 2003, 4:12:25 AM1/15/03
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On Sat, 11 Jan 2003 19:08:45 GMT, "Denis Marier" <mar...@nbnet.nb.ca>
wrote:

>Do you mean lactose intolerant?

>The small amount of lactose will be unnoticeable.
>Yes. this may be right. Taking one 300mg tablet of ferrous sulfate loaded
>with lactose as a filler will not affect an individual who is lactose
>intolerant. One of my friend who is lactose intolerant confirmed it.
>However, taking two ferrous sulfate tablets each day of the year may not be
>tolerated as one tablet each week. The thinks that intrigues me is why load
>the tablet with lactose filling.

Why not. It is apparently a cheap, effective, innocuous binder.
It is NOT cumulative. So how can an unnoticed amount each day cause
any more problem than the same amount weekly, unless you only take a
dump on a weekly basis.


Groper

Sangroper

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Jan 15, 2003, 4:22:42 AM1/15/03
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As I said?
But how often has this scenario ever occurred?


Groper

Denis Marier

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Jan 15, 2003, 8:29:38 AM1/15/03
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It may be so. But why use a binder that increases the size of a tablet by
about 70% in size.
The Quality Assurance Dept at the customer service stated that a certain
amount of sugar is mixed with the binder. When I asked how much sugar the
customer service replied about 1 1/2 % of sugar is in each of the tablet but
were unable to confirm the exact quantity. I am still awaiting the
confirmation. Again it may not raise the BG of a diabetic but if the
quantity is much larger it may?

"Sangroper" <#@$.&> wrote in message
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Sangropah

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Jan 15, 2003, 9:04:12 AM1/15/03
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On Wed, 15 Jan 2003 13:29:38 GMT, "Denis Marier" <mar...@nbnet.nb.ca>
wrote:

>It may be so. But why use a binder that increases the size of a tablet by
>about 70% in size.

You would have to ask a manufacturing pharmacy, but you need something
that will bind the constituents into a mechanically stable tablet.
That will not react with the constituents, and not taste bad or
otherwise upset the swallower. Many other considerations.

>The Quality Assurance Dept at the customer service stated that a certain
>amount of sugar is mixed with the binder. When I asked how much sugar the
>customer service replied about 1 1/2 % of sugar is in each of the tablet but
>were unable to confirm the exact quantity. I am still awaiting the
>confirmation. Again it may not raise the BG of a diabetic but if the
>quantity is much larger it may?

What are we talking about? A few miligrams of sugar? Much much less
than one calorie? You couldn't weigh one hundred times that amount in
the average kitchen. It really is insignificant.


Gropah

Denis Marier

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Jan 15, 2003, 10:05:49 AM1/15/03
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Your logic is good. However, why going into the expense of increasing the
size of the tablets while other manufacturer's are only 1/3 in size. Plus
the fact that no one has an explicit explanation as to the content. The
chemistry is described as Ferrous compound?
What really is in the ferrous compound is the manufacturer's secret. Taking
into consideration that ferrous sulfate has been around a long time the
ingredients should be well labeled. If not, some manufacturers may be
getting away with selling 300mg tablets while only containing 60% (or so) of
elementary iron. Which may explain the pharmacists reluctance to provide
more detailed information. I did not purchased ferrous sulfate because I
tough my system needed it. I went to a series of tests to find out that I
have pernicious ferrous anemia and was given a prescription for 300mg
tablets twice per day.

"Sangropah" <S@S.S> wrote in message
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Alf Christophersen

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Jan 15, 2003, 11:42:25 AM1/15/03
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On Wed, 15 Jan 2003 09:22:42 GMT, Sangroper <#@$.&> wrote:

>As I said?
>But how often has this scenario ever occurred?

Difficult to say, may be the main reason for allergies towards milk,
may be not.

Sugars in aldehyde form may be quite reactive to side groups of
proteins, mostly the amine/amide side chains.

Eric Bohlman

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Jan 15, 2003, 3:26:32 PM1/15/03
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Sangropah <S@S.S> wrote in
news:v8qa2vgamf3vcd95o...@4ax.com:

> What are we talking about? A few miligrams of sugar? Much much less
> than one calorie? You couldn't weigh one hundred times that amount in
> the average kitchen. It really is insignificant.

I think the unstated question is "why use binders at all? Why not just
make a tablet containing nothing but the active ingredient?" The answer,
of course, is that such a "tablet" would resemble a speck of dust rather
than a tablet, but if you have no mental model for what quantities mean,
you don't realize that.

Alf Christophersen

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Jan 15, 2003, 4:32:10 PM1/15/03
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On Wed, 15 Jan 2003 15:05:49 GMT, "Denis Marier" <mar...@nbnet.nb.ca>
wrote:

>have pernicious ferrous anemia and was given a prescription for 300mg
>tablets twice per day.

Visit another lab! Or did you mean usual ferrous deficiency anemia.
Pernicious anemia is a B12 deficiency.

Denis Marier

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Jan 15, 2003, 5:55:14 PM1/15/03
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Further to several shilling tests I received one injection of B12 every
month.
After blood works and laboratory analysis of my stools it was determined
that I also was iron deficient.
Quote: I have pernicious ferrous anemia Unquote
Should have read: I have ferrous anemia.
The B12 injection is for pernicious anemia amongst other things.
Hopefully after a while I will be able to stop taking B12 injections and
ferrous sulfate.


"Alf Christophersen" <alf.chris...@basalmed.uio.no> wrote in message

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