Diet And Liver Disease
ironjustice
Dietary influences of liver disease
Diets high in protein and cholesterol are associated
with a higher risk of hospitalization or death due to
cirrhosis or liver cancer, while diets high in
carbohydrates are associated with a lower risk.
These findings are in the July issue of Hepatology,
a journal published by John Wiley & Sons on behalf of
the American Association for the Study of Liver Diseases
(AASLD).
The article is also available online at Wiley Interscience
(www.interscience.wiley.com).
There are many reasons to suspect that dietary factors
influence the development of hepatic steatosis and its
progression to more severe liver disease.
First, poor diet may lead to obesity, insulin resistance
and diabetes, which are the most important known risk
factors for hepatic steatosis.
Also, dietary lipids may directly affect fat in the liver.
Furthermore, a high cholesterol diet has been shown to
induce serious steatosis in animal studies.
Researchers, led by George Ioannou of Veterans Affairs
Puget Sound Health Care System in Seattle, investigated
whether dietary nutrient composition was associated with
the subsequent development of cirrhosis or liver cancer
in a representative sample of the U.S. population.
They utilized data from 9,221 participants in the
National Health Examination Survey who had completed a
24-hour dietary recall questionnaire.
Participants were excluded if they suffered from cirrhosis
or liver cancer at the start of the study, or received a
diagnosis within five years.
During the follow-up period, an average of 13.3 years,
123 participants received a new diagnosis of cirrhosis
(118 people) or liver cancer (5 people) according to
hospitalization records and death certificates.
These individuals were more likely to be older, more
obese with more central fat distribution.
They had lower educational attainment and higher alcohol
consumption, and were more likely to be male, diabetic and
non-white.
Dietary nutrient composition was a strong predictor of
hospitalization or death due to cirrhosis or liver cancer
in the U.S. population.
"In particular, we identified that protein and cholesterol
consumption were associated with elevated risk, whereas
consumption of carbohydrates was associated with reduced
risk of hospitalization or death related to cirrhosis or
liver cancer," the authors report.
The association with cholesterol intake is potentially the
most important finding of this study, the authors suggest.
While cholesterol is well-known for its role in non-hepatic
diseases like atherosclerosis, it has never before been
linked to human liver disease.
The findings suggest that drugs blocking intestinal
cholesterol absorption might reduce the progression of fatty
liver disease but this needs to be investigated in prospective
studies.
"Subgroup analyses showed that the significant associations
of protein, carbohydrate and cholesterol intake with cirrhosis
or liver cancer that we described in the entire study population,
were limited to overweight or obese persons," the authors report.
"No such associations were observed in normal-weight persons.
" This suggests that the relevant dietary factors are more likely
to have hepatic effects through obesity-related fatty liver disease.
"Our study raises the possibility that dietary factors may be
important, modifiable, and hitherto unrecognized determinants
of liver disease progression," the authors conclude.
Article: "The Association Between Dietary Nutrient Composition
and the Incidence of Cirrhosis or Liver Cancer in the U.S.
Population." Ioannou, George; Connole, Marah; Morrow, Olivia;
Lee, Sum. Hepatology; July 2009.
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/634q5a
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
ad hominem
keyboard. You need to go into rehab for your crack cocaine addiction.
You are an illiterate spamming tosser with no hope of redemption. You
would have more luck of finding redemption with Allah. You use the
internet as your personal weapon of mass destruction. You copy and
paste research that is frequently flawed. The research often does NOT
relate to the subject line. Just because a piece of research is found
on PubMed it does not mean it is not flawed. I will always cut your
spam when posting a reply to your tripe. At first I found it hilarious
to see someone so delusional, illiterate (that was sad), and a veiled
attempt to extrapolate a conclusion from research that even the
primary researchers had no intention of doing. Tom you think you are
God sent (a delusion), intelligent (another delusion) and you think
people respect your opinion (another delusion). Three strikes you’re
out. So fuck off Tom you crack head queer.
Tom the crack head pillow biter even has a webpage devoted to him at
http://kook.us/tom-hennessy.htm
ironjustice
snip <<
Im sorry predators cannot be heard over the sound of how
awesome I am.
ironjustice
li...@oinions.net
of protein, carbohydrate and cholesterol intake with cirrhosis
or liver cancer that we described in the entire study population,
were limited to overweight or obese persons," the authors report.
"No such associations were observed in normal-weight persons.
" This suggests that the relevant dietary factors are more likely
to have hepatic effects through obesity-related fatty liver disease."
There you have it, obesity is the cause.
ironjustice
The article is about diet and progression of disease ..
You somehow think it relates to the cause of the disease .. ?
Jeez .. write to them ..
Tell them what they .. missed .. and how .. YOU .. spotted it ..
Make sure you tell them to .. spell .. your .. name .. right ..
Don't cut my posts ..
li...@oinions.net
You somehow think it relates to the cause of the disease .. ?
Jeez .. write to them .."
Oh, the disease just popped out of the blue without cause. It was they
who made the specific point to highlight the cause of the disease, take
it up with them.
""Subgroup analyses showed that the significant associations
of protein, carbohydrate and cholesterol intake with cirrhosis
or liver cancer that we described in the entire study population,
were limited to overweight or obese persons," the authors report.
"No such associations were observed in normal-weight persons.
" This suggests that the relevant dietary factors are more likely
to have hepatic effects through obesity-related fatty liver disease."
There you have it, obesity is the cause.
ad hominem
will cut your dribble.
Waterspider
ironjustice
wrote:snip <<
Im sorry predators cannot be heard over the sound of how
awesome I am.