Uh, I think that really is Don Wiley's Swine Flu.

[Mort Zuckerman]

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Subject: Uh, I think that really is Don Wiley's Swine Flu.

Date: Dec 21, 2011 12:58 PM

See:
http://www.actionlyme.org

Virology. 2012 Jan 5;422(1):105-13. Epub 2011 Nov 5.

In vitro evolution of H5N1 avian influenza virus toward human-type
receptor specificity.
Chen LM, Blixt O, Stevens J, Lipatov AS, Davis CT, Collins BE, Cox
NJ, Paulson JC, Donis RO.
Source

Influenza Division, Centers for Disease Control and Prevention,
1600 Clifton Road, Atlanta, GA 30333, United States.
Abstract

"Acquisition of α2-6 sialoside receptor specificity by α2-3
specific highly-pathogenic avian influenza viruses (H5N1) is thought
to be a prerequisite for efficient transmission in humans. By in vitro
selection for binding α2-6 sialosides, we identified four variant
viruses with amino acid substitutions in the hemagglutinin (S227N,
D187G, E190G, and Q196R) that revealed modestly increased α2-6 and
minimally decreased α2-3 binding by glycan array analysis. However, a
mutant virus combining Q196R with mutations from previous pandemic
viruses (Q226L and G228S) revealed predominantly α2-6 binding. Unlike
the wild type H5N1, this mutant virus was transmitted by direct
contact in the ferret model although not by airborne respiratory
droplets. However, a reassortant virus with the mutant hemagglutinin,
a human N2 neuraminidase and internal genes from an H5N1 virus was
partially transmitted via respiratory droplets. The complex changes
required for airborne transmissibility in ferrets suggest that
extensive evolution is needed for H5N1 transmissibility in humans.



DON WILEY (2001, before he was murdered):

"α2,6-Linked sialosides bind in a cis conformation, exposing the
glycosidic oxygen to solution and nonpolar atoms of the receptor to
Leu-226, a human-specific residue. ...

"Evidently, the “closed” geometry of the avian H5 HA, which
prefers α2,3 linkages, results from the Gln-226/Gly-228 pair. This
geometry appears optimal for positioning Gln-226 to hydrogen-bond to
the α2,3 trans motif composed of the 4-OH of Gal-2 and the glycosidic
oxygen (Fig. ​(Fig.22c). The human H3 HA with the Leu-226/Ser-228 pair
is at the opposite extreme, more “open” at both 228 and 226, which may
be optimal for Leu-226 to make nonpolar contacts to α2,6 cis linkages.
Swine H9 HA (Leu-226/Gly-228) and the L226Q variant of human H3 HA
(Gln-226/Ser-228) appear to be intermediate, with partial avian and
partial human character and the nonstandard Leu/Gly and Gln/Ser pairs
(Fig. ​(Fig.22f)."

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC58807/?tool=pubmed



So, it seems to me that they simply made a swine flu out of an avian
flu.


Pandemic flu: "Reassortant viruses appear to have caused the
pandemics of 1957 and 1968; the 1957 H2 virus differed by three genes,
those for HA, NA and the RNA polymerase subunit PB1, from the H1 virus
that infected humans between 1918 and 1957; the 1968 H3 virus differed
by two genes, those for HA and PB1, from the H2 virus that infected
humans between 1957 and 1968 (Kawaoka et al., 1989). In both cases,
the genes for the H2 and H3 HAs are proposed to have been contributed
by avian viruses, during infection of an unknown host that was
infected simultaneously by the prevalent human virus."
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC125880/?tool=pubmed


Unknown host being a pig?

I could be wrong, of course, but it looks like they made the H5N1 into
an H9 Swine flu.

Regardless, the story with the ferrets meant the
new flu with the H9 2,6 sialoside....


This data was in the data package stolen off
of Richard Blumenthal's desk by AAG Jessica
Gauvin (the Oct 4, 2003 Lyme RICO datapackage)
which was a copy mailed to the US Attorney's
office.
http://www.actionlyme.org/BLUMENTHALS_MAIL_STOLEN_BY_JESSICA_GAUVIN.htm

It contained the images of the overlapping
binding sites of the various flus, showing
that the H9 formation would take the least
change - a lesser mutation than that of an
avian flu - to "take" to human cells.

Glad that's all now out in the open.


We've known about this Wiley report since
it was published in 2001, since pandemics
and Lyme lies seem to go together. We wondered
what the hell else the CDC and NIH were lying
about...






Kathleen M. Dickson