Soy better than Cheese - depends on which fat you put in your body!
Taka
lifespan seem to be mediated by the arachidonic acid (AA) as well ...
The milk protein casein (basically cheese) is rich in methionine but
the soy protein is low in methionine. Methionine stimulates the
desaturases which are making AA if you put the vegetable oil into your
body (containing the AA precursor linoleic acid). If you put only
saturated fat into your body, the desaturases will manufacture the
Mead acid instead which is not proinflammatory. The Mead acid is also
far less susceptible to lipid peroxidation/lipofuscin production than
the Omega-3 series which the fish oil salesmen here will try to
recommend you instead.
Taka
Bioscience, Biotechnology, and Biochemistry
Vol. 67 (2003) , No. 4 pp.743-751
Increased Response of Liver Microsomal Δ6-Desaturase Activity to
Dietary Methionine in Rats
The effects of dietary casein level (5-40%) on the liver microsomal
phospholipid profile, Δ6-desaturase activity and related variables
were investigated in rats to examine whether the dietary protein level
affected the Δ6-desaturase activity through an alteration of the liver
microsomal phospholipid profile. The effects of supplementing a 10%
casein diet with certain amino acids were also investigated. The
concentration of hepatic S-adenosylmethionine (SAM), the ratio of
phosphatidylcholine (PC) to phosphatidylethanolamine (PE) and the Δ6-
desaturase activity in liver microsomes, and the ratio of arachidonate
to linoleate of microsomal PC increased with increasing dietary casein
level. There were significant correlations between the dietary
methionine content and hepatic SAM concentration, hepatic SAM
concentration and microsomal PE concentration, and microsomal PE
concentration and Δ6-desaturase activity. Supplementation of the 10%
casein diet with methionine significantly increased the hepatic SAM
concentration, PC/PE ratio, Δ6-desaturase activity, and arachidonate/
linoleate ratio, whereas cystine supplementation had no or little
effect on these variables. These increases induced by methionine were
significantly suppressed by additional glycine. The results obtained
here, together with those in our previous report, suggest that
quantity and type of dietary protein might affect the Δ6-desaturase
activity through an alteration of the liver microsomal profile of
phospholipids, especially PE, and that the alteration of phospholipid
profile might be mediated by a hepatic SAM concentration that reflects
the dietary methionine level.
SOURCE: http://www.jstage.jst.go.jp/article/bbb/67/4/67_743/_article/-char/en
(full text very interesting!)
ironj...@aol.com
The milk protein casein (basically cheese) is rich in methionine but
the soy protein is low in methionine. <<
That statement would be about as correct as your .. "meat is high in
phosphate" .. take on the whole deal .. eh ..
One might wonder if you get ALL your information out of sci.med.life-
extension ..
"Normal usage of soy protein, methionine supplementation is
unnecessary"
Soy protein in relation to human protein and amino acid nutrition.
AU Young VR
SO J Am Diet Assoc 1991 Jul;91(7):828-35.
The nutritional value of processed soy protein (isolated soy
proteins and soy-protein concentrates) in human protein and amino acid
nutrition is evaluated on the basis of a review of studies of growth
and nitrogen balance in infants, children, adolescents, and adults.
Findings show that well-processed soy-protein isolates and soy-protein
concentrates can serve as the major, or even sole, source of protein
intake and that their protein value is essentially equivalent to that
of food proteins of animal origin. The importance of the sulfur amino
acid content of soy protein for practical human nutrition is also
examined from nitrogen-balance data. Under conditions of an
anticipated normal usage of soy protein, methionine supplementation is
not only unnecessary but may even be undesirable for young children
and adults. However, for newborns, the data suggest that modest
supplementation of soy-based formulas with methionine may be
beneficial. Soy proteins have also been found to be of good quality to
include in hypocaloric diets for weight reduction in obese subjects.
Finally, the data indicate that soy proteins are well-tolerated and of
good acceptability.
AD Laboratory of Human Nutrition, School of Science, Massachusetts
Institute of Technology, Cambridge 02139.
PMID 2071798
-------------------------
New study backs soy’s bone protection benefits
By Lorraine Heller, 20-Jan-2009
Related topics: Research, Proteins, peptides, amino acids, Bone &
joint health
Soy protein consumption could help protect against bone loss in post
menopausal women, suggests a new study that adds to previous findings
linking soy to bone health in women.
Published in the December 2008 issue of Osteoporosis International,
the study followed over 400 perimenopausal Chinese women for 30 months
to investigate change in bone mineral density and its determinants.
The findings revealed that the fastest bone loss occurred in women
undergoing menopause – but that soy protein intake seemed to exert a
positive effect on bone health, together with maintenance of body
weight and physical fitness.
Soy and bone health
Limiting bone loss in post-menopausal women could ease the burden of
osteoporosis, a disease that affects half of all women over the age of
50. According to the International Osteoporosis Foundation, the total
direct cost of osteoporotic fractures is €31.7 bn in Europe alone.
Previous studies have reported conflicting results concerning soy
isoflavones (40 to 99 mg/d doses) and bone health for postmenopausal
women. But a recent meta-analysis added to the debate by reporting
that such doses of soy isoflavones (less than 90 mg/d) may improve
bone density (Clinical Nutrition, doi:10.1016/j.clnu.2007.10.012).
Moreover, other studies from China have linked soy isoflavones to
increases in bone mineral density (BMD), and a recent large study in
the Archives of Internal Medicine (2005, Vol. 165, pp. 1890-1895)
reported that high soy consumption was linked with a 48 per cent
decrease in fractures for women who had been menopausal for less than
10 years.
New findings
The new study recruited 438 Hong Kong Chinese women, aged 45 to 55
through random telephone dialling and primary care clinic. Researchers
took bone mass, body composition and lifestyle measurements at
baseline and at 9-, 18- and 30-month follow-ups.
Menopausal status was classified as pre- or postmenopausal or
transitional. Using multiple regression analyses derived from baseline
and follow-up measurements, the researchers found that menopausal
status was the strongest determinant of bone changes.
Premenopausal women had an annual bone loss of around 0.5 per cent.
Women in the ‘transitional’ group had 2 to 2.5 per cent bone loss, and
postmenopausal women recorded around 1.5 per cent loss.
“Multiple regression analyses, revealed that a positive regression
slope of body weight was protective for follow-up bone loss at all
sites. Number of pregnancy, soy protein intake and walking were
protective for total body BMC. Higher baseline LM was also protective
for neck of femur BMD,” wrote the researchers.
Source:
‘Change in bone mineral density and its determinants in pre- and
perimenopausal Chinese women: the Hong Kong perimenopausal women
osteoporosis study’Osteoporosis International, Volume 19, Number 12 /
December, 2008
DOI10.1007/s00198-008-0614-2
Authors: Ho SC, Chan SG, Yip YB, Chan CS, Woo JL, Sham A.
Department of Community and Family Medicine, The Chinese University of
Hong Kong, 4/F School of Public Health, Prince of Wales Hospital,
Shatin, NT, Hong Kong.
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
> Methionine stimulates the
> desaturases which are making AA if you put the vegetable oil into your
> body (containing the AA precursor linoleic acid). If you put only
> saturated fat into your body, the desaturases will manufacture the
> Mead acid instead which is not proinflammatory. The Mead acid is also
> far less susceptible to lipid peroxidation/lipofuscin production than
> the Omega-3 series which the fish oil salesmen here will try to
> recommend you instead.
>
> Taka
>
> Bioscience, Biotechnology, and Biochemistry
> Vol. 67 (2003) , No. 4 pp.743-751
>
> Increased Response of Liver Microsomal Ä6-Desaturase Activity to
> Dietary Methionine in Rats
>
> The effects of dietary casein level (5-40%) on the liver microsomal
> phospholipid profile, Ä6-desaturase activity and related variables
> were investigated in rats to examine whether the dietary protein level
> affected the Ä6-desaturase activity through an alteration of the liver
> microsomal phospholipid profile. The effects of supplementing a 10%
> casein diet with certain amino acids were also investigated. The
> concentration of hepatic S-adenosylmethionine (SAM), the ratio of
> phosphatidylcholine (PC) to phosphatidylethanolamine (PE) and the Ä6-
> desaturase activity in liver microsomes, and the ratio of arachidonate
> to linoleate of microsomal PC increased with increasing dietary casein
> level. There were significant correlations between the dietary
> methionine content and hepatic SAM concentration, hepatic SAM
> concentration and microsomal PE concentration, and microsomal PE
> concentration and Ä6-desaturase activity. Supplementation of the 10%
> casein diet with methionine significantly increased the hepatic SAM
> concentration, PC/PE ratio, Ä6-desaturase activity, and arachidonate/
> linoleate ratio, whereas cystine supplementation had no or little
> effect on these variables. These increases induced by methionine were
> significantly suppressed by additional glycine. The results obtained
> here, together with those in our previous report, suggest that
> quantity and type of dietary protein might affect the Ä6-desaturase
Taka
> On Jan 21, 12:38 am, Taka <taka0...@gmail.com> wrote:
> The milk protein casein (basically cheese) is rich in methionine but
> the soy protein is low in methionine. <<
>
> That statement would be about as correct as your .. "meat is high in
> phosphate" .. take on the whole deal .. eh ..
>
> One might wonder if you get ALL your information out of sci.med.life-
> extension ..
actually this came from here:
http://www.imminst.org/forum/index.php?showtopic=9303
> "Normal usage of soy protein, methionine supplementation is
> unnecessary"
The question was not whether soy protein causes malnutrition but
whether consuming large amounts of cheese could be dangerous. There
are some claims that avoiding the dairy improves cardiovascular
health.
Taka
ironjustice
not whether soy protein causes malnutrition but whether consuming
large amounts of cheese could be dangerous. <<
I didn't notice a question ..
I .. did notice though .. the .. "soy protein is low in methionine" ..
part and felt that I should point out the .. seemingly .. constant ..
wrong information .. emanating from your threads ..
THAT is why I questioned your .. sources .. IE: "clioquinol doesn't
chelate iron"
ironjustice
I .. did notice though .. the .. "soy protein is low in
methionine" .. <<
"high levels of methionine in soy proteins"
Taka
> On Jan 21, 5:43 pm, ironjustice <ironjust...@cashette.com> wrote:
> I .. did notice though .. the .. "soy protein is low in
> methionine" .. <<
>
> http://tinyurl.com/cdu4tw
>
> "high levels of methionine in soy proteins"
Numbers, numbers, Tom. "High levels" compared to what, casein? I
doubt it. Here are some numbers extracted from other threads:
cheddar cheese 33g protein 861 mg methionine
whey protein 17g protein 380 mg methionine
soy protein 17g protein 238 mg methionine
so soy is roughly 1/2 methionine than casein what is actually good in
the modern diet context ...
Also look at this:
doi:10.1016/j.mehy.2008.07.044
The low-methionine content of vegan diets may make methionine
restriction feasible as a life extension strategy
Recent studies confirm that dietary methionine restriction increases
both mean and maximal lifespan in rats and mice, achieving “aging
retardant” effects very similar to those of caloric restriction,
including a suppression of mitochondrial superoxide generation.
Although voluntary caloric restriction is never likely to gain much
popularity as a pro-longevity strategy for humans, it may be more
feasible to achieve moderate methionine restriction, in light of the
fact that vegan diets tend to be relatively low in this amino acid.
Plant proteins – especially those derived from legumes or nuts – tend
to be lower in methionine than animal proteins. Furthermore, the total
protein content of vegan diets, as a function of calorie content,
tends to be lower than that of omnivore diets, and plant protein has
somewhat lower bioavailability than animal protein. Whole-food vegan
diets that moderate bean and soy intake, while including ample amounts
of fruit and wine or beer, can be quite low in methionine, while
supplying abundant nutrition for health (assuming concurrent B12
supplementation). Furthermore, low-fat vegan diets, coupled with
exercise training, can be expected to promote longevity by decreasing
systemic levels of insulin and free IGF-I; the latter effect would be
amplified by methionine restriction – though it is not clear whether
IGF-I down-regulation is the sole basis for the impact of low-
methionine diets on longevity in rodents.
doi:10.1016/S0305-7372(03)00118-X
Methionine dependency and cancer treatment
Conventional chemotherapies have showed their limits, notably for
patients with advanced cancer. New therapeutic strategies must be
identified, and the metabolic abnormalities of cancer cells offer such
opportunities. Many human cancer cell lines and primary tumors have
absolute requirements for methionine, an essential amino acid. In
contrast, normal cells are relatively resistant to exogenous
methionine restriction. The biochemical mechanism for methionine
dependency has been studied extensively, but the fundamental mechanism
remains unclear. A number of investigators have attempted to exploit
the methionine dependence of tumors for therapeutic effects in vivo.
To reduce in vivo methionine in plasma and tumours, dietary and
pharmacological treatments have been used. Methionine-free diet or
methionine-deprived total parenteral nutrition causes regression of a
variety of animal tumours. Alternatively, methionine depletion was
achieved by the use of methioninase. This enzyme specifically degrades
methionine and inhibits tumour growth in preclinical models. Because
of potential toxicity and quality of life problems, prolonged
methionine restriction with diet or with methioninase is not suitable
for clinical use. Methionine restriction may find greater application
in association with various chemotherapeutic agents. Several
preclinical studies have demonstrated synergy between methionine
restriction and various cytotoxic chemotherapy drugs. The experimental
results accumulated during the last three decades suggest that
methionine restriction can become an additional cancer therapeutic
strategy, notably in association with chemotherapy.
Taka
ironjustice
Numbers, numbers, Tom. "High levels" compared to what, casein? I
doubt it. Here are some numbers extracted from other threads: <<
I'm going to just quit believing anything I read and just accept the
fact eating plants .. is good .. and work from there.
Dairy .. the tyramine in the cheese can cause some issues .. and one
could extrapolate animal foods to pharmaceutical in that the animals
body changes substances into drugs in their bodies .. IE: substances
not normally found in such high concentration in plants.
Just as an example .. mannose and maltose ..
They tell you to take them with water when oil is what they
spontaneously combine with.
Sooo .. either they FAIL to tell you this on purpose or they are too
stupid to tell you this .. or they don't KNOW that .. mannose and
maltose spontaneously form into the oils.
Therefore if one looks at another instance of .. ? .. quercitin which
is absorbed at what was it 10X the rate when taken with .. oil .. ?
In any of those instances one can see that they are of no help at all
and in one of those instances they are being underhanded / on purpose
withholding information.
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
>