Marijuana appears to counterintuitively restore GI barrier integrity in colitis
Kofi
for _Alien_ and _Dark Star_ as well as a Crohn's sufferer. His obit
said he got the idea for a monster springing out of the gut from the way
his stomach rumbled.
Cool. My afflication has a film score by Jerry Goldsmith. (No wonder
Veronica Cartwright always gives me that look.)
"So I said, '#$*@!%(@!#%(!#(, Doolittle...' And he didn't get it."
"Benson, Arizona... my body flies the galaxy/ my heart longs to be
there..."
<http://www.sciencedaily.com/releases/2009/12/091220175502.htm>
Cannabis Hope for Inflammatory Bowel Disease
ScienceDaily (Dec. 21, 2009) � Chemicals found in cannabis could prove
an effective treatment for the inflammatory bowel diseases Ulcerative
Colitis and Crohn's Disease, say scientists.
Laboratory tests have shown that two compounds found in the cannabis
plant -- the cannabinoids THC and cannabidiol -- interact with the
body's system that controls gut function.
Crohn's Disease and Ulcerative Colitis, which affect about one in every
250 people in Northern Europe, are caused by both genetic and
environmental factors. The researchers believe that a genetic
susceptibility coupled with other triggers, such as diet, stress or
bacterial imbalance, leads to a defective immune response.
Dr Karen Wright, Peel Trust Lecturer in Biomedicine at Lancaster
University, presented her soon-to-be published work at The British
Pharmacological Society's Winter Meeting in London.
She said: "The lining of the intestines provides a barrier against the
contents of the gut but in people with Crohn's Disease this barrier
leaks and bacteria can escape into the intestinal tissue leading to an
inappropriate immune response.
"If we could find a way to restore barrier integrity in patients we may
be able to curb the inflammatory immune response that causes these
chronic conditions."
Dr Wright, working with colleagues at the School of Graduate Entry
Medicine and Health in Derby, has shown that cells that react to
cannabinoid compounds play an important role in normal gut function as
well as the immune system's inflammatory response.
"The body produces its own cannabinoid molecules, called
endocannabinoids, which we have shown increase the permeability of the
epithelium during inflammation, implying that overproduction may be
detrimental," said Dr Wright.
"However, we were able to reverse this process using plant-derived
cannabinoids, which appeared to allow the epithelial cells to form
tighter bonds with each other and restore the membrane barrier."
The research was carried out using cell cultures in a dish but,
interestingly, when the team attempted to mimic the conditions of the
gut by reducing the amount of oxygen in the cells' environment, much
lower concentrations of cannabinoid were needed to produce the same
effect.
Dr Wright added: "What is also encouraging is that while THC has
psychoactive properties and is responsible for the 'high' people
experience when using cannabis, cannabidiol, which has also proved
effective in restoring membrane integrity, does not possess such
properties."
------------------------------------------------------------------------
Story Source:
Adapted from materials provided by British Pharmacological Society, via
AlphaGalileo.
Van Chocstraw
> On a sad note, Dan O'Bannon has passed away. He was the screenwriter
> for _Alien_ and _Dark Star_ as well as a Crohn's sufferer. His obit
> said he got the idea for a monster springing out of the gut from the way
> his stomach rumbled.
>
> Cool. My afflication has a film score by Jerry Goldsmith. (No wonder
> Veronica Cartwright always gives me that look.)
>
> "So I said, '#$*@!%(@!#%(!#(, Doolittle...' And he didn't get it."
>
> "Benson, Arizona... my body flies the galaxy/ my heart longs to be
> there..."
>
> <http://www.sciencedaily.com/releases/2009/12/091220175502.htm>
>
> Cannabis Hope for Inflammatory Bowel Disease
>
I'd just as soon get high at the same time as protecting my gut. You
don't mind do you?
Kofi
> I'd just as soon get high at the same time as protecting my gut. You
> don't mind do you?
It will worsen your risk of neurodegeneration, psychosis/schizophrenia,
testicular cancer, lung cancer (if you smoke it) and other problems. I
think that's why the researchers went out of their way to point out the
benefits extended to unusually low doses.
Van Chocstraw
Obviously you are wrong when health people are walking around that have
smoked marijuana for over 50 years. Millions of them. There is your
control test.
Kofi
Chocstraw <boobooil...@roadrunner.com> wrote:
What about the dead ones?
> There is your
> control test
No. Your control test is to conduct a scientific survey of people
abusing addictive drugs. If you're unable to look at the statistics and
see these associations between pot smoking and psychosis or testicular
cancer it's because your brain is wedded to this addiction, doesn't want
to give it up and wants to live in denial of the risks. Just because we
wish reality were different, it doesn't magically change to suit us.
Things that feel good aren't always the things that are good for us.
Ted
> In article <4oidncEX_pK4VK3WnZ2dnUVZ_sxi4...@giganews.com>, Van
How easy is it to filter out the pot smokers who also used other
drugs, including alcohol, and the ones who only smoked pot? And I seem
to remember having read about a couple of studies that showed no
increase risk of cancer among marijuana smokers. And that it surprised
the researchers. Some think that pot is an anticarcinogen.
http://www.lewrockwell.com/orig5/armentano-p1.html
However, I am not suggesting that smoking anything is perfectly safe.
But maybe an occasional toke or two isn't such a bad thing.
Gail Michael
properties it is loaded with. It actually causes Crohns disease and
Ulcerative Colitis. Not to the smoker but to a friend or relative when
ingesting it or any pschiatric stimulant by sending stress by the mind to
the innocent person causing them to have crohns or UC.
That is a fact. Will discuss it further another day if that day arrives.
Kureforcrohns
Rufus
...after ending up in counciling as a victim of domestic violence once I
finally walked away (with Crohn's) from a habitual marijuana user, whom
also had me putting up with dissociative personality and mood swings,
all I have to say is that I will NEVER AGAIN allow anyone that uses that
mind-poison to form any sort of close connection to me or become a
continuing participant in my life...nor will I EVER consider allowing
that crap into my own body.
Yeah - it's personal. And other than the above, I'm not interested in
any discussion.
--
- Rufus
Ted
It causes Crohns Disease? ,,Oh please.
I can tell you something about alcohol. It is a hard drug. The
withdrawal symptoms are far more dangerous than Heroin. Your blood
pressure will rise to stroke level, you will shake uncontrollably, you
will hallucinate....(maybe see flying, screaming, bloody heads coming
at you through the air, or worms crawling in and out of your skin),
have seizures, and maybe die of a stroke. You will most definitely end
up with permanent brain damage....possibly leading to
korsakoff's...wearing a diaper and staring at the wall 24/7. You will
be far more likely to cause a car accident or indulge in some kind of
violent behavior.....including rape. And your family will suffer in
ways that you would never see from a marijuana smoker.
That being said, I do not smoke marijuana. But I am a recovering
alcoholic and I know the difference.. But I see nothing wrong with an
occasional toke off of a joint or an occasional drink. And if alcohol
remains legal, then certainly marijuana should be legal as well.
Kofi
Actually, any smoking probably activates aryl-hydrocarbon receptors on
macrophages, impairing their ability to function. This leaves them
unable to clear bacteria out of the gut lining the way they usually do
and unable to patrol the lungs for precancerous cells. Just as
cigarette smoking increases risk for Crohn's and lung cancer (even
second hand), it's likely marijuana smoke would do the same. Even if
the individual concerned only ate marijuana for the effect, it could
still induce psychosis or depress executive function in a way that could
lead to spousal abuse which would in turn, no doubt, lead to stress for
all parties concerned...
I see no reason to distinguish between alcohol and marijuana addiction.
Both are addictive drugs that act on dopamine circuits to produce a
high. Both create their own peculiar hells and both strike people in
uneven ways. Some people simply have a higher tolerance and are less
likely to become addicted or suffer damage. Others aren't as lucky.
It's unwise to generalize from personal circumstances to the broader
population.
M
>
> No. Your control test is to conduct a scientific survey of people
> abusing addictive drugs.
Spot the hysteria...?
ABUSING ADDICTIVE DRUGS
Not just people 'taking cannabis', but
ABUSING ADDICTIVE DRUGS
M
Gail Michael
uncanny ability to cause crohns by stress of the mind going from one person
to another.
Simple , but hardly known or believable process to cause crohns or
Ulcerative Colitis. Not so with alcohol, just perhaps the outer abuse it
causes by overusing the drug. A person is smart to stay away from drug
addicts (if possible) Unfortunately, their mind when on the stimulant is
dangerous to the person thought of and nothing can be done.
Big subject and increasing in numbers.
The pharms must ban the anti-depressants as they are the most common cause
of crohns. But will they ever?
Nursing homes get the worse abuse by using anti-depressants. Inorganic
diseases have increased to the innocent residents like diabetes, mental and
physical deterioration and are ill for no reason they can understand.
These are circumstances unrelated to their original illness. A terrible
injustice to the innocent.
Gail
Gail Michael
psychiatric stimulant if it didn't harm someone else rather than the person
using it. These drugs DO cause crohns or UC to an innocent friend or
relative ingesting the stimulant. Alcohol is not in this category. The
mind is the transference of the stress causing crohns to an innocent person.
Gail
Van Chocstraw
Enough with the boogyman theories.
Ted
> > It causes Crohns Disease? ,,Oh please.
>
> Actually, any smoking probably activates aryl-hydrocarbon receptors on
> macrophages, impairing their ability to function. This leaves them
> unable to clear bacteria out of the gut lining the way they usually do
> and unable to patrol the lungs for precancerous cells. Just as
> cigarette smoking increases risk for Crohn's and lung cancer (even
> second hand), it's likely marijuana smoke would do the same. Even if
> the individual concerned only ate marijuana for the effect, it could
> still induce psychosis or depress executive function in a way that could
> lead to spousal abuse which would in turn, no doubt, lead to stress for
> all parties concerned.
Oh please. There is no comparison. It's like comparing Charlie Manson
to someone with bad breath. Having a bad day at work could lead to
spousal abuse by that kind of logic. I have decades of first hand
knowledge of people smoking pot, drinking, and abusing drugs. Compared
to alcohol, spousal abuse from a person who smokes a joint is almost
non-existent. It actually has the opposite effect.
> I see no reason to distinguish between alcohol and marijuana addiction.
I do. Because people who smoke a joint might go to jail.....even
though it does not even scratch the surface of the harm that is
created by alcohol abuse.
> Both are addictive drugs that act on dopamine circuits to produce a
> high.
Do you really believe that pot addiction and alcohol addiction even
similar? Trust me, they are worlds apart. With marijuana, you crave it
for about 3 days. that's it. You can literally die from alcohol
withdrawal. Piss and shit all over yourself, shake violently, and die
of a stroke.
>Both create their own peculiar hells and both strike people in
> uneven ways. Some people simply have a higher tolerance and are less
> likely to become addicted or suffer damage. Others aren't as lucky.
> It's unwise to generalize from personal circumstances to the broader
> population.
As with alcohol, most people who smoke pot, smoke it occasionally
without issue. But if you are ever stuck with the choice of having a
pot smoker drive you home, or a drinker....you had best choose the pot
smoker if you value your life.
Ted
Alcohol causes far more harm to your body and mind than marijuana.
zumone2002
email and web sites are out of date
It can be found in the Internet Archive
http://web.archive.org/web/20041028115411/ascc.healingwell.com/info/gailfaq.htm
which also details Gail's "Theory"
--
Luke
Who is Gail Michael and what is her theory on the cause of Crohn's
Disease?
Gail Michael is an elderly woman who lives in Chicago. Gail believes
that a person contracts Crohn's Disease when close friends and
relatives
on what she terms "uppers" (she includes antidepressants, asthma
medications and marijuana) think a lot about the affected person.
According to Gail, physical and/or verbal contact are unnecessary; if
a
close friend or relative thinks intensely about someone while that
close
friend or relative is on these drugs, then that is what is causing you
to suffer from Crohn's, even if you totally break off your
relationship
with that person. Your own drug use has nothing to do with this
theory;
rather, some sort of telepathy between the drug-taker and the person
with Crohn's appears to be at work.
Prior posts of Gail's have indicated (in no particular order) that
1. She believes people on what she terms "uppers" can also give pets
Crohn's Disease if they think a lot about the pets.
2. At least one physician has counselled her to see a psychiatrist but
she refuses.
3. She has broken off several friendships believing that this people
were causing her Crohn's by thinking intently about her while on
drugs.
4. She once had stomach pains that she believed were caused by a
nephew
who was taking an antidepressant after his wife died, and that she
believes ceased because her nephew committed suicide, and therefore
was
no longer taking antidepressants.
5. She once accused a man of causing his sister-in-law to have a
stroke
and die because he refused to stop using marijuana. The man told her
that he hadn't touched marijuana in 25 years.
Why is there a FAQ about Gail Michael?
Gail often replies to newbie posts by detailing her theory in a way
that
some find difficult to understand and that many, for various
reasons,
find provocative in the full sense of that word. Replies to her
posts
often constitute flaming, which is disturbing to those who look for
emotional support in this newsgroup. More importantly, she has taken
to
targeting newbies, especially newbies with suffering children, by
email.
This is a group in particular need of strong positive emotional
support
and information; what they don't need is for their first email after
posting to be disturbing enough to stop them from visiting the
newsgroup.
What is the solution?
The best solution in this imperfect world is to REFRAIN FROM POSTING
in
reply to Gail.
This FAQ will be posted every time Gail Michael posts so that the
person
she is replying to knows exactly what her theory is.
To people who find her theory interesting or provocative in either a
positive or negative way, PLEASE, don't post. Please email Gail
directly
with your comments or questions at . If you feel the need to
complain
about her posts, the address to complain to is ab...@prodigy.net. Be
polite and include examples of her posts and the reason why they're a
problem.
To people who find this FAQ interesting or provocative in either a
positive or negative way, PLEASE, don't post. Please email me
directly
at s...@panix.com. Also email me if you want backup as to anything I
have posted in this FAQ, and I will be happy to email you past posts
of
Gail's I have saved that back up all of these statements.
Ted
Gail Michael
Alcohol causes far more harm to your body and mind than marijuana.
You do not get the point. Yes, alcohol causes far more harm to the PERSON
INGESTING THE ALCOHOL. Try to understand the marijuana, anti-depressants
that one person is ingesting transfers harm in the form of crohns to
someone the person ingesting the alcohol knows and thinks of no matter where
in the world that second person is - by stress of the mind. The alcoholic
suffers no illness other than what alcohol can naturally do to their mind
and body. They do not contract crohns or UC.
Understand? strange but true.
Gail
Gary R. Schmidt
> This used to be available online, I think this copy is from 2004
> email and web sites are out of date
>
Thanks for posting the Gail Michael FAQ - I've been away from Usenet
over the Yaksmas - New Year break, otherwise I would have.
I don't think it could be considered to be out of date, she has been
posting her drek in alt.support.crohns-colitis since at least the mid-
to late-1990's (when I got here), and it has not changed.
She has scared a lot of people away from a.s.c-c, often by directly
emailing them, and so on.
To those of you in other newsfroups who have now been introduced to our
loon, sorry.
Cheers,
Gary B-)
Gail Michael
that discourages people from at least looking into a method that may help
their crohns or UC. Too bad, but our opposite views are important to some
that are not closed to the unusual method of developing crohns and UC.
"Gary R. Schmidt" <grsc...@acm.org> wrote in message
news:3fo317-...@paranoia.mcleod-schmidt.id.au...
Gary R. Schmidt
> The only drek I know is the Gary R.Schmidt on this group. You are the one
> that discourages people from at least looking into a method that may help
> their crohns or UC. Too bad, but our opposite views are important to some
> that are not closed to the unusual method of developing crohns and UC.
Now, now Gail - you *know* that I do not discourage people from looking
into alternative methods of dealing with IBD - I own a "Zapper", I've
looked into many variant treatments, and my basic attitude is "What
works for you works for you."
Where you, of course, have suggested "stopping all their medication" to
newcomers to a.s.c-c, have harassed people by email, and DO NOT HAVE IBD.
So, back into the kill-file you go (presumably you had to change ISP,
again), and I fervently hope that you follow this path in real life shortly.
Cheers,
Gary B-)
Gail Michael
are all suffering from crohns or UC, so why would I do anything to make them
worse.
I just happen to go by my own theory, but I still have a lot of damage from
crohns. Because I am unable to shake the people that continue to use
psychiatric stimulants and still think of me. Why I do not know. Of
course I try to never see them but occasionally they come to my house and
expect to be let in, which is out of the qustion. Why I attract drug
addicts is something I do not understand.
I will not even take an anti-depressant because that will cause someone to
suffer crohns. Believe it or not, that IS the cause of crohns. I wish
it were not.
It takes matters out of our hands and thus becomes impossible at times to
negate the situation.
Gail
And incidentally, I had to switch ISP because AT&T discontinued the usenet.
"Gary R. Schmidt" <grsc...@acm.org> wrote in message
news:jeh617-...@paranoia.mcleod-schmidt.id.au...
Gail Michael
Gail Michael
Read the post by Rufus on 12/23.
Am I reading wrong or is this somewhat a verification of what I am saying.
Gail
"Gary R. Schmidt" <grsc...@acm.org> wrote in message
news:3fo317-...@paranoia.mcleod-schmidt.id.au...
Gail Michael
Are you saying that some with marijuana use gave you crohns. I have been
saying that for years. It is the same with all anti-depressants including
Xanax, causing crohns or UC. I try to stay away from almost everyone who
uses a psychiaric stimulant. Not easy to do because anti-depressants are so
common.
I hope Gary Schmidt reads this column
Gail
.
"Rufus" <n...@home.com> wrote in message
news:CtOdnd1smrSle6_W...@mchsi.com...
Rufus
What I'm saying is that dealing with the aggravation of someone that
was/became near to psychotic and distinctly dissociative while using
marijuana put me though enough stress that by the time I got smart
enough to walk away from them I ended up hospitalized, bleeding, and
near to a pan-colectomy within three months of walking away and getting
counciling for that abuse...after which I ended up on medical disability
for six months, recovering. Then it took another year for me to finally
be positively diagnosed with Crohn's.
What I liken my experience to is an extreme case of what someone goes
though as a continual caregiver - stress can not only debilitate, it can
kill given enough quantity and time. No thanks - not for something as
stupid as dope, or for anyone stupid enough to use it.
If I sound angry it's because I am...I lost enough blood that my
hemoglobin count was down to 8.2; 12-14 is considered normal, and
estimates were that I lost 1/3 of my blood volume...a dope smoker nearly
killed me, and it's not going to happen again. Ever.
And as for any "benefit", I'll personally die screaming before I allow
it in my own body.
And as fas as alcohol goes - I bet my ex that I could stop drinking
faster than she could stop smoking dope...I stopped, she lied...if it
weren't for my doctor telling me to drink red wine, I wouldn't even do
that, as I had given up alcohol totally because of this experience and
just plain lost my taste for it...now I drink it as medicine, and I
don't like it.
--
- Rufus
Gail Michael
can't get the SOB to stop thinking of me. That is all it takes. It is an
illness of the mind.
I think I would have this man beaten up if I could. I am losing my hair,
hearing, teeth etc. I never had anything to do with him except some
friendly verbal exchanges. he insisted on coming into my house which is out
of the question now. I live a life of fear and despondency.
Gail Michaelnews:gbmdnXprB6lBL9_W...@mchsi.com...
Rufus
...I own guns.
Gail Michael
I wish I had the nerve.
Gail
"Rufus" <n...@home.com> wrote in message
news:Xt-dnXen9PWvbN7W...@mchsi.com...