In article <45f5a51d.26658
...@news1.news.adelphia.net>, J. Hugh Sullivan wrote:
> Irish Sullivans are usually Haplo Group R1b; western Asia and eastern
> Europe Sullivans are Vikings and are Haplo Group R1a - I am R1a.
> If Adam was the first man why don't all males have the same DNA (with
> mutations)?
They do mostly. The differences are caused by mutations.
> If O'Suilebhain was the first Sullivan and we all descend from him,
> how can Sullivans be more than one Haplo type?
Note that you should be specific that this is Y chromosome
Haplogroups.
Several possibilities
1. The type split after him (unlikely)
2. adoption (e.g., an O'Sullivan with no sons adopted his sister's son
or his daughter's son as heir or even an unrelated male and that man
took the O'Sullivan name but the heir and his male male line
descendants would not have the Y chromosome of the initial man)
3. Adultery or rape. Some of an O'Sullivan's sons weren't actually
his biological sons due to his wife being impregnated by another man.
4. There was more than one initial O'Suilebhain
> Or might variations in Haplo Groups be caused by mutations?
Yes
> Be gentle, I'm not very bright.
Well it starts with four compounds
called:
*adenine (A)
*cytosine (C)
*guanine (G)
*thymine (T)
These can combine to form base pairs but adenine only matches with
thymine and guanine only with cytosine. The base pairs in turn form a
chain of any combination of pairs
...
AT
GC
TA
AT
AT
CG
TA
TA
GC
AT
AT
GC
TA
TA
CG
GC
...
This is called DNA and it encodes the genetic information and that
with a few additional bits can make up chromosomes (a chromosome may
have a few million to hundreds of millions of these pairs).
A human has multiple chromosome pairs (23 pairs or 46 chromosomes in
total). For all but one pair the following holds true:
1. That each partner in a pair is identical in size.
2. During the formation of an egg or sperm cell (a process known as
meiosis)
2a. Each pair exchanges pieces so if one pair was initially
aaaaaaa and bbbbbb
afterwards they might be
aaabbb and bbbaaa or abbbb and baaaa
(I'm simplifying here and not actually using the base pair
nomenclature)
They 'recombine'.
The exception is the XY chromosome pair in a male human (the
equivalent XX pair in female humans does recombine). Because the X
chromosome and the Y chromosome aren't the same size they don't really
recombine and the Y chromosome doesn't change (except by mutation).
2b. The cell divides into two cells each with one partner in each
chromosome pair (i.e., it has half the chromosomes of a normal cell);
these cells are the eggs cells in women and the sperm cells in men.
For men 50% of the sperm cells would contain an X chromosome and 50% a
Y chromosome.
In fertilization a sperm cell and an egg cell combine to form a new
cell with the correct number of chromosomes. Assuming this new cell
develops into a full human being those that had an XY pair will become
males and those with XX females. Note the Y chromosome is identical
(barring mutations) to that of the father.
And so the generations go on. All the other chromosomes recombine
each generation but in the male line the Y chromosome doesn't change
(barring mutations).
Now as to haplogroups, one can look at a Y chromosome and read its
base pair makeup and compare to another Y chromosome. So
aaabcededagh
is similar except for one letter to
aaabcedeaagh
but quite distinct from
babbeedeaaca
(again I'm simplifying and not using the correct nomenclature)
haplogroups are just groups of similar Y chromosomes. Note that not
all Y chromosomes in the same group will be identical but the
differences were not considered significant when defining the group.
So for instance the two groups you are concerned with, R1a and R1b,
are subsets of group R1 which is a subset of group R which is a
subgroup of group K which is a subset of group F and so on till
eventually you have a group that includes all human Y chromosomes (and
all human males).
The mutation that distinguishes between R1a and R1b are not considered
significant when defining R. Mutations btw are when the copy of the
DNA structure isn't completely accurate for instance abcddccdb is
copied as abcddccdc.
http://en.wikipedia.org/wiki/Haplogroup_R_%28Y-DNA%29
has a list of which mutations are used to define which subgroups
within R.
Also see
https://www3.nationalgeographic.com/genographic/atlas.html
So going backwards
Group Mutation/Marker When
-----------------------------
R1a M17 ~10,000 to ~15,000 before present (BP)
R1 M173 ~30,000 BP in Central Asia
R M207 ~30,000 BP in Central Asia
P M45 ~35,000 to 40,000 BP in Central Asia
K M9 ~40,000 BP in Iran/Central Asia
F M89 ~45,000 BP in North Africa or Mid-East
M168 31,000 to 79,000BP in Africa
Note that you have all these mutations and you share them with other
groups (for instance R1b has M173, M207... also but not M17).
I'm not sure how to explain the dating discrepancy but this is still
an area which scientists are arguing about specifics.
Also take what I say above with a grain of salt, I'm not a biologist.
Emma
ps. you might find http://news.bbc.co.uk/2/hi/uk_news/6293333.stm
interesting.
pps. I assume you also got a group for your mitochondrial DNA?
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