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RQFTCINO13 Game 2, Rounds 2-3: drugs and streets

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Mark Brader

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Sep 22, 2022, 7:08:08 AM9/22/22
to
These questions were written to be asked in Toronto on 2013-02-04,
and should be interpreted accordingly. All questions were written
by members of the Night Owls, but have been reformatted and may
have been retyped and/or edited by me. I will reveal the correct
answers in about 3 days.

For further information, including an explanation of the """
notation that may appear in these rounds, see my 2022-09-09
companion posting on "Reposted Questions from the Canadian
Inquisition (RQFTCI*)".


* Game 2, Round 1 - Current Events (excerpt)

Answer these 2013 questions if you like for fun, but for no points.

1. Which film won the top honor for best overall cast performance
at the Screen Actors Guild (SAG) awards last week?

2. Who replaced Hillary Clinton as the US secretary of state
last week?


* Game 2, Round 2 - Science - Drugs from Plants or Animals

About 50% of the prescription drugs used """today""" were originally
extracted from plant or animal sources.

1. Aspirin or ASA was originally extracted from which plant source?

2. Taxol, also known by its generic name paclitaxel, is one of the
most important cancer drugs. Discovered at the National Cancer
Institute in the US in 1962, it was launched by Bristol Myers
in 1992. For the first 20 years of its development it could
only be obtained from the bark and leaves of which tree?

3. Premarin is an estrogen-containing drug that that was one
of the first to treat symptoms of menopause also called hormone
replacement therapy or HRT. When it was first introduced to
the market, it was extracted from what?

4. Penicillin was the first antibiotic and played a major role
in ending the reign of infectious diseases as the leading cause
of death. Penicillin was discovered in 1928 by Scottish doctor
Alexander Fleming. He discovered and isolated it from a common
contaminant of his bacterial cultures. What contaminant?

5. In the 1890s scientists at Bayer discovered and marketed
a powerful painkiller that competed with Aspirin. This drug,
extracted from a common red flower, had a trademarked name: what?

6. One of the most potent nerve toxins known to mankind has killed
millions of people who have eaten spoiled food contaminated with
the bacteria that produce this toxin. This nerve toxin has
been purified and is used routinely today in medical clinics.
What is the trademarked name of this drug?

7. A chemical found in the bark of the cinchona tree was used
by Quechua Indians of Peru and Bolivia to fight infection by
the malaria parasite. British colonials in India added it
to a medicinal water to fight malaria, and combined it with a
little gin to moderate the taste -- the origin of gin-and-tonic.
This drug is still an important anti-malarial today. What is it?

8. Hockey celebrity Don Cherry """swears by""" ColdFX. This product
was a groundbreaking over-the-counter cold medicine, since it
was the first natural health product sold in Canada to back up
its claims with proper clinical trials carried out at university
hospitals. ColdFX is actually an extract of which plant?

9. The fertility drugs Menotropin, Menupur, and Repronex contain
follicle-stimulating hormone (FSH) to stimulate maturation
of eggs and ovulation in women having difficulty in becoming
pregnant. The FSH in these drugs until relatively recently
was commercialy obtained from what source?

10. Galantamine is a drug used to treat the early stages of
Alzheimer's disease. It was discovered in the 1950s in Bulgaria
and was produced from the bulbs of which plant family?

After completing the round, please decode the rot13: Vs nal fbhepr
lbh zragvbarq jnf yvzvgrq gb n fcrpvsvp traqre bs cynag be navzny,
lbh zhfg anzr gung traqre. Vs nal fbhepr lbh zragvbarq vf hevar,
lbh zhfg anzr gur fcrpvrf cebqhpvat vg. Naq vs nal fbhepr lbh
zragvbarq vf zbyq, lbh zhfg fnl jung xvaq. Cyrnfr tb onpx naq
svyy va gur zvffvat arprffnel qrgnvyf.


* Game 2, Round 3 - Canadiana Geography - Toronto Streets

This round is about Toronto streets that flow directly into
another street.

1. Where does Bloor St. E. change into Danforth Av.?
2. Carlton St. changes into what street at Yonge St.?
3. Davenport Rd. changes into what street at Yonge?
4. York Mills Rd. changes into what avenue at Yonge?
5. Traveling east, Eastern Av. ends by curving to become which road?
6. Near which major cross avenue does Danforth Rd. merge into
McCowan Rd.?

7. Traveling east, Lake Shore Blvd. E. ends by curving to become
which avenue?

8. Traveling northbound on Beverly St., it changes to become what
street at College St.?

9. Traveling south on Mt. Pleasant Rd., just after crossing
Bloor St. this road merges into what street continuing south?

10. Traveling westbound on Front St. E., the street splits into two
at Church St. Front becomes one-way eastbound, and what street
takes the westbound traffic?

--
Mark Brader | "What can be more palpably absurd than the prospect held out
Toronto | of locomotives travelling twice as fast as stagecoaches?"
m...@vex.net | -- The Quarterly Review (England), March 1825

My text in this article is in the public domain.

Joshua Kreitzer

unread,
Sep 23, 2022, 12:04:17 AM9/23/22
to
On Thursday, September 22, 2022 at 6:08:08 AM UTC-5, Mark Brader wrote:

> * Game 2, Round 1 - Current Events (excerpt)
>
> Answer these 2013 questions if you like for fun, but for no points.
>
> 2. Who replaced Hillary Clinton as the US secretary of state
> last week?

John Kerry

> * Game 2, Round 2 - Science - Drugs from Plants or Animals
>
> About 50% of the prescription drugs used """today""" were originally
> extracted from plant or animal sources.
>
> 1. Aspirin or ASA was originally extracted from which plant source?

willow bark

> 3. Premarin is an estrogen-containing drug that that was one
> of the first to treat symptoms of menopause also called hormone
> replacement therapy or HRT. When it was first introduced to
> the market, it was extracted from what?

mares' urine

> 4. Penicillin was the first antibiotic and played a major role
> in ending the reign of infectious diseases as the leading cause
> of death. Penicillin was discovered in 1928 by Scottish doctor
> Alexander Fleming. He discovered and isolated it from a common
> contaminant of his bacterial cultures. What contaminant?

Penicillium mold

> 5. In the 1890s scientists at Bayer discovered and marketed
> a powerful painkiller that competed with Aspirin. This drug,
> extracted from a common red flower, had a trademarked name: what?

Heroin (?)

> 6. One of the most potent nerve toxins known to mankind has killed
> millions of people who have eaten spoiled food contaminated with
> the bacteria that produce this toxin. This nerve toxin has
> been purified and is used routinely today in medical clinics.
> What is the trademarked name of this drug?

Botox

> 7. A chemical found in the bark of the cinchona tree was used
> by Quechua Indians of Peru and Bolivia to fight infection by
> the malaria parasite. British colonials in India added it
> to a medicinal water to fight malaria, and combined it with a
> little gin to moderate the taste -- the origin of gin-and-tonic.
> This drug is still an important anti-malarial today. What is it?

quinine


> After completing the round, please decode the rot13: Vs nal fbhepr
> lbh zragvbarq jnf yvzvgrq gb n fcrpvsvp traqre bs cynag be navzny,
> lbh zhfg anzr gung traqre. Vs nal fbhepr lbh zragvbarq vf hevar,
> lbh zhfg anzr gur fcrpvrf cebqhpvat vg. Naq vs nal fbhepr lbh
> zragvbarq vf zbyq, lbh zhfg fnl jung xvaq. Cyrnfr tb onpx naq
> svyy va gur zvffvat arprffnel qrgnvyf.

Qbar!

> * Game 2, Round 3 - Canadiana Geography - Toronto Streets

No answers in this round.

--
Joshua Kreitzer
grom...@hotmail.com

Dan Tilque

unread,
Sep 23, 2022, 6:07:54 AM9/23/22
to
On 9/22/22 04:08, Mark Brader wrote:
>
>
> * Game 2, Round 1 - Current Events (excerpt)
>
> Answer these 2013 questions if you like for fun, but for no points.
>
> 1. Which film won the top honor for best overall cast performance
> at the Screen Actors Guild (SAG) awards last week?
>
> 2. Who replaced Hillary Clinton as the US secretary of state
> last week?
>
>
> * Game 2, Round 2 - Science - Drugs from Plants or Animals
>
> About 50% of the prescription drugs used """today""" were originally
> extracted from plant or animal sources.
>
> 1. Aspirin or ASA was originally extracted from which plant source?

willows

>
> 2. Taxol, also known by its generic name paclitaxel, is one of the
> most important cancer drugs. Discovered at the National Cancer
> Institute in the US in 1962, it was launched by Bristol Myers
> in 1992. For the first 20 years of its development it could
> only be obtained from the bark and leaves of which tree?

yew

>
> 3. Premarin is an estrogen-containing drug that that was one
> of the first to treat symptoms of menopause also called hormone
> replacement therapy or HRT. When it was first introduced to
> the market, it was extracted from what?
>
> 4. Penicillin was the first antibiotic and played a major role
> in ending the reign of infectious diseases as the leading cause
> of death. Penicillin was discovered in 1928 by Scottish doctor
> Alexander Fleming. He discovered and isolated it from a common
> contaminant of his bacterial cultures. What contaminant?

penicillium yeast

>
> 5. In the 1890s scientists at Bayer discovered and marketed
> a powerful painkiller that competed with Aspirin. This drug,
> extracted from a common red flower, had a trademarked name: what?

Tylenol

>
> 6. One of the most potent nerve toxins known to mankind has killed
> millions of people who have eaten spoiled food contaminated with
> the bacteria that produce this toxin. This nerve toxin has
> been purified and is used routinely today in medical clinics.
> What is the trademarked name of this drug?

Botox

>
> 7. A chemical found in the bark of the cinchona tree was used
> by Quechua Indians of Peru and Bolivia to fight infection by
> the malaria parasite. British colonials in India added it
> to a medicinal water to fight malaria, and combined it with a
> little gin to moderate the taste -- the origin of gin-and-tonic.
> This drug is still an important anti-malarial today. What is it?

quinine

>
> 8. Hockey celebrity Don Cherry """swears by""" ColdFX. This product
> was a groundbreaking over-the-counter cold medicine, since it
> was the first natural health product sold in Canada to back up
> its claims with proper clinical trials carried out at university
> hospitals. ColdFX is actually an extract of which plant?
>
> 9. The fertility drugs Menotropin, Menupur, and Repronex contain
> follicle-stimulating hormone (FSH) to stimulate maturation
> of eggs and ovulation in women having difficulty in becoming
> pregnant. The FSH in these drugs until relatively recently
> was commercialy obtained from what source?
>
> 10. Galantamine is a drug used to treat the early stages of
> Alzheimer's disease. It was discovered in the 1950s in Bulgaria
> and was produced from the bulbs of which plant family?

lily
Dan Tilque

Dan Blum

unread,
Sep 24, 2022, 1:05:35 AM9/24/22
to
Mark Brader <m...@vex.net> wrote:

> * Game 2, Round 1 - Current Events (excerpt)

> 2. Who replaced Hillary Clinton as the US secretary of state
> last week?

John Kerry

> * Game 2, Round 2 - Science - Drugs from Plants or Animals

> 1. Aspirin or ASA was originally extracted from which plant source?

willow bark

> 4. Penicillin was the first antibiotic and played a major role
> in ending the reign of infectious diseases as the leading cause
> of death. Penicillin was discovered in 1928 by Scottish doctor
> Alexander Fleming. He discovered and isolated it from a common
> contaminant of his bacterial cultures. What contaminant?

bread mold

> 5. In the 1890s scientists at Bayer discovered and marketed
> a powerful painkiller that competed with Aspirin. This drug,
> extracted from a common red flower, had a trademarked name: what?

morphine

> 6. One of the most potent nerve toxins known to mankind has killed
> millions of people who have eaten spoiled food contaminated with
> the bacteria that produce this toxin. This nerve toxin has
> been purified and is used routinely today in medical clinics.
> What is the trademarked name of this drug?

Botox

> 7. A chemical found in the bark of the cinchona tree was used
> by Quechua Indians of Peru and Bolivia to fight infection by
> the malaria parasite. British colonials in India added it
> to a medicinal water to fight malaria, and combined it with a
> little gin to moderate the taste -- the origin of gin-and-tonic.
> This drug is still an important anti-malarial today. What is it?

quinine

> 10. Galantamine is a drug used to treat the early stages of
> Alzheimer's disease. It was discovered in the 1950s in Bulgaria
> and was produced from the bulbs of which plant family?

crocus; tulip

--
_______________________________________________________________________
Dan Blum to...@panix.com
"I wouldn't have believed it myself if I hadn't just made it up."

Mark Brader

unread,
Sep 25, 2022, 4:05:37 PM9/25/22
to
Mark Brader:
> These questions were written to be asked in Toronto on 2013-02-04,
> and should be interpreted accordingly... For further information...
> see my 2022-09-09 companion posting on "Reposted Questions from
> the Canadian Inquisition (RQFTCI*)".


> * Game 2, Round 1 - Current Events (excerpt)

> Answer these 2013 questions if you like for fun, but for no points.

> 1. Which film won the top honor for best overall cast performance
> at the Screen Actors Guild (SAG) awards last week?

"Argo".

> 2. Who replaced Hillary Clinton as the US secretary of state
> last week?

John Kerry. Joshua and Dan Blum got this.


> * Game 2, Round 2 - Science - Drugs from Plants or Animals

> About 50% of the prescription drugs used """today""" were originally
> extracted from plant or animal sources.

> 1. Aspirin or ASA was originally extracted from which plant source?

Willow (bark). 4 for everyone -- Joshua, Dan Tilque, and Dan Blum.

I left the original wording intact here, but I'm pretty sure it
should've said "derived from". As I understand it, the willow
contains *salicylic* acid; the Bayer company's great innovation was
to add an acetyl group to the molecule, producing a much lower level
of stomach irritation.

> 2. Taxol, also known by its generic name paclitaxel, is one of the
> most important cancer drugs. Discovered at the National Cancer
> Institute in the US in 1962, it was launched by Bristol Myers
> in 1992. For the first 20 years of its development it could
> only be obtained from the bark and leaves of which tree?

(Pacific) yew. 4 for Dan Tilque.

> 3. Premarin is an estrogen-containing drug that that was one
> of the first to treat symptoms of menopause also called hormone
> replacement therapy or HRT. When it was first introduced to
> the market, it was extracted from what?

The urine of pregnant horses. "Mares' urine" was sufficient.
4 for Joshua.

> 4. Penicillin was the first antibiotic and played a major role
> in ending the reign of infectious diseases as the leading cause
> of death. Penicillin was discovered in 1928 by Scottish doctor
> Alexander Fleming. He discovered and isolated it from a common
> contaminant of his bacterial cultures. What contaminant?

Penicillium green bread mold. "Mold" together with any one of the
other words was sufficient. 4 for Joshua and Dan Blum.

> 5. In the 1890s scientists at Bayer discovered and marketed
> a powerful painkiller that competed with Aspirin. This drug,
> extracted from a common red flower, had a trademarked name: what?

Heroin. 4 for Joshua.

> 6. One of the most potent nerve toxins known to mankind has killed
> millions of people who have eaten spoiled food contaminated with
> the bacteria that produce this toxin. This nerve toxin has
> been purified and is used routinely today in medical clinics.
> What is the trademarked name of this drug?

Botox. 4 for everyone.

> 7. A chemical found in the bark of the cinchona tree was used
> by Quechua Indians of Peru and Bolivia to fight infection by
> the malaria parasite. British colonials in India added it
> to a medicinal water to fight malaria, and combined it with a
> little gin to moderate the taste -- the origin of gin-and-tonic.
> This drug is still an important anti-malarial today. What is it?

Quinine. 4 for everyone.

> 8. Hockey celebrity Don Cherry """swears by""" ColdFX. This product
> was a groundbreaking over-the-counter cold medicine, since it
> was the first natural health product sold in Canada to back up
> its claims with proper clinical trials carried out at university
> hospitals. ColdFX is actually an extract of which plant?

(American) ginseng.

He's still alive, but I have no idea what he swears by now.

> 9. The fertility drugs Menotropin, Menupur, and Repronex contain
> follicle-stimulating hormone (FSH) to stimulate maturation
> of eggs and ovulation in women having difficulty in becoming
> pregnant. The FSH in these drugs until relatively recently
> was commercialy obtained from what source?

Urine of menopausal nuns. "Women's urine" was sufficient.

Drug companies paid for the urine by volume and felt that nuns were
less likely than other women to cheat by diluting it.

> 10. Galantamine is a drug used to treat the early stages of
> Alzheimer's disease. It was discovered in the 1950s in Bulgaria
> and was produced from the bulbs of which plant family?

Daffodil or (spider) lily. 4 for Dan Tilque.


> * Game 2, Round 3 - Canadiana Geography - Toronto Streets

In 2013 I noted that the rest of you could blame Stephen Perry
for this round not being thrown out. This time he didn't post an
entry, and nobody else got anything in this round, so it *is* being
thrown out.

> This round is about Toronto streets that flow directly into
> another street.

> 1. Where does Bloor St. E. change into Danforth Av.?

At the Don Valley. (Any reference indicating that location was
acceptable.)

> 2. Carlton St. changes into what street at Yonge St.?

College St.

> 3. Davenport Rd. changes into what street at Yonge?

Church St.

> 4. York Mills Rd. changes into what avenue at Yonge?

Wilson Av.

> 5. Traveling east, Eastern Av. ends by curving to become which road?

Kingston Rd.

> 6. Near which major cross avenue does Danforth Rd. merge into
> McCowan Rd.?

Lawrence Av.

> 7. Traveling east, Lake Shore Blvd. E. ends by curving to become
> which avenue?

Woodbine Av.

> 8. Traveling northbound on Beverly St., it changes to become what
> street at College St.?

St. George St.

> 9. Traveling south on Mt. Pleasant Rd., just after crossing
> Bloor St. this road merges into what street continuing south?

Jarvis St.

> 10. Traveling westbound on Front St. E., the street splits into two
> at Church St. Front becomes one-way eastbound, and what street
> takes the westbound traffic?

Wellington St.


Scores, if there are no errors:

GAME 2 ROUNDS-> 2
TOPICS-> Sci
Joshua Kreitzer 24
Dan Tilque 20
Dan Blum 16
--
Mark Brader, Toronto "If it's on TV, it has to be true!
m...@vex.net (I read that on the Internet.)"
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