That makes sense to me, and is where I was going. You could get deep
agents who've been biologically tailored to blend in, suddenly develop a
virulent and opposition specific disease at, say 35. They wouldn't have
to enter any particular social circle, in fact it would be better if
they went for maximum dispersion inside the opposing country, so the
plague would kick already in spread out to it's furthest geophysical reach.
I know that isn't a sanity issue, but simply a possible genetic
engineering outcome. But you could bounce it up to the planners. What
sort of mindset goes through with creating a "normal" member of a
society who will one day spread deadly contagion, never knowing that she
was designed that way?
With truly effective design, you could get a culture of human shaped
killer wasps who take over other cultures and breed true, you could get
a culture of true libertarians who agree on what that is, and will drive
out anybody who tries to gain a mass consensus on any subject that the
libertarian group disapproves of. You could see cultures of people
who've built genetic markers in themselves to force them to breed true
to their favored racial markers.
Some groups would attempt to develop genetic predisposition to martyrdom
for a particular vision of God/Allah/Yahweh. Others might find it
easier to make everybody genetically loyal to their Savior here on Earth.
Genetically enhanced asteroid miners, love the solitude, don't breath
much except when motion is called for, make a pilgrimage to earth two or
three times in their lives. They love it here for the tourism/sexual
stimulation, but are made island crazy within a couple weeks. A utopia
in which everybody is designed to love a certain job, and the only
controversy is in how to design people with unique specializations who
nonetheless share a strand of common humanity and loyalty to the larger
human hive.