Thanks for your answer Jonathan. I agree with you. For staging/production, fabric is the way to go, even though I haven't taken time to learn it properly yet.
For development, ....our team is really young and new to Python, linux for that matter. I'm in China, everyone uses Windows here. I wanted a one step solution such that it doesn't change their workflow as to how they start up their development Pyramid application (they still continue to use pserve --reload development.ini).
I think I'll combine your answer with `somewhattofftheway` and add it to the postactivate file of virtualenvwrapper.
Thanks everyone!