pylons-discuss - join
Pylons is a Python Web Framework aimed at making development, distribution, and deployment faster and easier.
Low activity, 1949 members

Django developers - join
Discussion group for Django developers. This group is used for discussion of developing Django itself, not user questions; Please use django-users for issues regarding using the framework, questions for the Django user community outreach, etc.
Low activity, 5004 members

TurboGears - join
Discussion about the TurboGears front-to-back web development megaframework.
Medium activity, 3644 members