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Article Title: Miscarriage and Risks For Later Heart Disease and Stroke
Author: Joy Cutler
Word Count: 516
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Most women who suffer miscarriages may feel sadness and a sense of loss in addition to the physical symptoms they must cope with, but, surprisingly, there are cardiovascular risks as well. A recently completed study from Copenhagen, Denmark, showed that women who have a miscarriage or a stillbirth (where the baby dies before birth) are more likely to suffer from atherosclerosis later in life. Atherosclerosis, as any cardiologist will quickly point out, is a risk factor for serious types of heart disease or myocardial infarction (heart attack).
The Danish study examined medical records from more than 1 million women between the years of 1977 and 2008 to look for risk factors and cardiac events following either a miscarriage or a stillbirth. The physicians running the study evaluated women for renal hypertension (a condition where high blood pressure occurs as a result of narrowing of the arteries that carry blood to the kidneys). They also looked for signs of myocardial infarction (heart attack), cerebrovascular infarction (stroke). The most shocking part of the study was the fact that women who had suffered miscarriages had experienced much higher rates of cardiovascular disease � and sometimes this occurred years later.
Some of the statistics are revealing. For instance, women who had suffered a miscarriage had a 13% higher rate of both heart attack and stroke when compared with women who had never experienced a miscarriage. Women who had experienced miscarriages also had a 20% greater risk for renal hypertension as compared with those who hadn�t experienced a pregnancy loss. Even more stunning, those women who had given birth to stillborn babies had rates higher still when compared to baselines. The group who had experienced stillbirths had a 169% higher risk of heart attack, a 142% greater chance of experiencing renal hypertension, and a 74% greater risk for stroke.
The greater the number of miscarriages that women had, the more likely they were to suffer later heart disease or stroke, the researchers also discovered. The effects were apparently cumulative � meaning that each time they had another miscarriage or still birth their chances for heart attack, stroke, or renal hypertension were higher.
One puzzling part of this study is that so far, the reasons behind it remain a mystery. Generally, women experience lower rates of cardiovascular disease when compared to males, when all other factors are taken into consideration (such as obesity, smoking, and diabetes). One hypothesis is that underlying inflammation in the body can cause both miscarriages as well as negatively affect artery health (as increased plaque buildup leads to heart attack and stroke). Another factor that the researchers did not control for, but which could have been to blame, is preeclampsia, which may be a risk factor for later heart disease and stroke. Preeclampsia can also cause miscarriage and stillbirth, so it could have been an influencing factor. The authors plan to conduct more follow-up research to thoroughly investigate the role of preeclampsia.
To learn more about cardiology jobs and research into the field, view the links below or search your favorite engine for cardiology news and research.
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