Chemotherapy reduces cognitive function
My Name
Sun, 20 Dec 2009 15:14:03 GMT
Commonly used chemotherapy agents can disrupt the cognitive
function in cancer survivors through inhibiting the
regeneration of new brain cells.
Chemo brain, a debilitating condition reported in many
cancer survivors, is characterized by memory and
concentration problems, confusion, difficulty in multi-
tasking and slow thinking.
The condition may remain for weeks, months or years after
chemotherapy.
According to the study published in Cancer Investigation,
four commonly used chemotherapy drugs cross the blood-brain
barrier, disrupting the brain cell proliferation in the
animal model.
"It could be that all of the chemo drugs cross into the
brain after all, or that they act via peripheral mechanisms,
such as inflammation, that could open up the blood-brain
barrier," said lead researcher Robert Gross.
These agents are believed to destroy the ability of brain
cells to regenerate in the hippocampus, a brain region
responsible for memory formation and mood.
The condition could be partially reversed with the use of
the insulin-like growth factor IGF-1, the study finds.
PKH/HGH
Related Stories:
Milk thistle fights chemo-induced liver damage
Childhood cancer survivors at risk of heart disease
Ginger treats chemotherapy-related nausea
http://www.presstv.ir/detail.aspx?id=114222§ionid=3510210
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