pylons-discuss - join
Pylons is a Python Web Framework aimed at making development, distribution, and deployment faster and easier.
Low activity, 1949 members, restricted

comp.lang.python - join
The Python computer language.
Low activity, 16093 subscribers, Usenet

CodeMash - join
Group for CodeMash conference attendees. Use this group to discuss issues before, during, and after the event! This is a public group, so the sharing of personal information (like cell phone numbers) might be best done in email, with individual group members. Soliciting sales is prohibited.
Low activity, 378 members, restricted