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Description: A discussion group for anyone with an interest in Medical Statistics.
 

Estimating test retest and inter rater reliability 
  Dear All Is it possible to obtain estimates of test retest reliability and inter rater reliability using the following design? Time 1 Time 2 S1 rated by R1 S1 rated by R1 S2 rated by R1 S2 rated by R2 S3 rated by R2 S3 rated by R2... more »
By s.white@sgul.ac.uk  - Nov 17 - 1 new of 1 message    

Sample size for Repeated Measures 
  Dear all I am working on a Cohort study with Repeated Measures. I want to calculate sample size. How do I calculate the sample size? Thanks in advance
By ehsan sabaghian  - Nov 16 - 10 new of 10 messages    

sample size for sensitivity/specificity 
  I have a clinical test (positive/negative) and surgery (disease/not- diseased) and plan to calculate sensitivity/specificity. How do I estimate the sample size? Any advice would be greatly appreciated.
By Evie  - Nov 16 - 7 new of 7 messages    

{MEDSTATS} Confidence interval for ratio of independent binomial proportions 
  I'm willing to be that this is a pretty good indicator of the agency's thinking: New Tests for Null Hypothesis of Non Unity Ratio of Proportions Author: Kallappa M. Koti a Affiliation: a United States Food and Drug Administration, New Hampshire Avenue, Silver Spring, Maryland, USA DOI: 10.1080/10543400601177426... more »
By Frank Isackson  - Nov 13 - 2 new of 2 messages    

Confidence interval for ratio of independent binomial proportions 
  Can anyone give advice on the state of the art for estimating the confidence interval for the ratio of two independent binomial proportions (e.g., CI for a likelihood ratio)? An FDA guidance seems to be recommending 'exact' confidence intervals here, though I'm not sure what they mean -- maybe something available... more »
By John Uebersax  - Nov 13 - 13 new of 13 messages    

Simulation for sample size calculation 
  Dear all, I often get asked for simple sample size calculations, e.g. for a difference between two independent means or two independent proportions, however in the pursuit of greater accuracy I'd like to be able to run simulations to get my figures instead of relying on the standard formula. The trouble is I'm not sure of a (gentle) source of... more »
By JonStat  - Nov 13 - 3 new of 3 messages    

Recurrent events in the presence of a competing risk 
  Hi everyone I have a question. How can I analysis Recurrent events in the presence of a competing risk? Is there any book, website, software related to my problem? Best Ehsan Sabaghian
By ehsan sabaghian  - Nov 11 - 1 new of 1 message    

Bland-Altman-Plots in case of duplicates/replicates 
  Dear community, I'm wondering if there are specials aspects to consider if Bland- Altman plots are drawn for experiments when measurements are performed in duplicates (or more replicates) per method. One could use means, of course, but in that case information about precision is lost, and differences could become smaller in average.... more »
By Thomas Keller  - Nov 10 - 6 new of 6 messages    

Population Attributable Risk (PAR) from Cross Sectional Studies? 
  Hello Forumers: I have a question. I am trying to wrap my head around the calculation and use of Population Attributable Risk based on a cross sectional study. From my basic epidemiology courses, I have come to understand that such an estimate is only reasonable when one can make plausible assumptions of causality. Given that cross sectional studies are... more »
By Shaibu  - Nov 6 - 2 new of 2 messages    

{MEDSTATS} Trajectory modelling, useful with only two timepoints? 
  Thomas Fröjd <tfr...@gmail.com> wrote ...I've never used PROC TRAJ (never even heard of it) but I'd hesitate to call something with only two timepoints a trajectory. Patterns in recovery are too complex to be captured with only two time points. I am also leery of classifying number of symptoms into "low" and "high" unless there is a clear separation.... more »
By Peter Flom  - Nov 4 - 12 new of 12 messages    

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