Bland-Altman-Plots in case of duplicates/replicates

[Thomas Keller]

Dear community,

I'm wondering if there are specials aspects to consider if Bland-
Altman plots are drawn for experiments when measurements are performed
in duplicates (or more replicates) per method.
One could use means, of course, but in that case information about
precision is lost, and differences could become smaller in average.
But regarding single measurements, it is not possible to draw a point
for each single replicate, because they could be considered to be
random.

I look forward to your helpful comments,

Thank you Thomas

*****************
Th. Keller, www.acomed-statistik.de
Leipzig, Germany

[BXC (Bendix Carstensen)]

This problem is treated in:

@Article{Carstensen.2008b,
author = {B Carstensen and J Simpson and LC Gurrin},
title = {Statistical models for assessing agreement in method
comparison studies with replicate measurements},
journal = {International Journal of Biostatistics},
year = {2008},
volume = {4},
number = {1},
pages = {Article 16}
}
freely available as
http://www.bepress.com/cgi/viewcontent.cgi?article=1107&context=ijb

best regards,
Bendix Carstensen

[Frank Harrell]

Excellent paper. Glad to know about it Bendix.
Frank

On Nov 10, 12:44 pm, "BXC (Bendix Carstensen)" <b...@steno.dk> wrote:
> This problem is treated in:
>
> @Article{Carstensen.2008b,
>   author =       {B Carstensen and J Simpson and LC Gurrin},
>   title =        {Statistical models for assessing agreement in method
>   comparison studies with replicate measurements},
>   journal =      {International Journal of Biostatistics},
>   year =         {2008},
>   volume =       {4},
>   number =       {1},
>   pages =        {Article 16}}
>

> freely available ashttp://www.bepress.com/cgi/viewcontent.cgi?article=1107&context=ijb

[Thomas Keller]

Thank you - Thomas

[Luiz Alberto S. Melo Jr.]

Aspects about the analysis of multiple observations can be found in:

Bland JM, Altman DG. Agreement between methods of measurement with multiple
observations per individual. J Biopharm Stat. 2007;17(4):571-82.


Luiz

Luiz Alberto S. Melo Jr.
Department of Ophthalmology
Federal University of São Paulo
Brazil
luiza...@oftalmo.epm.br

[Thomas Keller]

Thanks, Luiz, in fact, the whole volume is of great interest in terms
of statistical analyses of method comparison experiments.
Thomas