Easily, you can save the gcode files to an SD card and just use the netbook to start the print.
I use pronterface to run the machine, slic3r 9.0 to handle all the slicing work, and Garmin SketchUp to make parts.
Sketchup has some massive shortcomings, but once you know how everything works, it is light and has a really nice workflow.
There is a write up on using the web interface of pronterface, but I haven't set that up yet. I just upgraded my router so I'm going to mount my old one on the printer and access the raspberry Pi that way.
Kliment did say he was going to make a version without the visualization, but I haven't heard yet how that is coming along. I may dig into the code and try to disable it myself if I get some free time :P