This month's tech meet will be at UCL on Wednesday the 21st of April
(not a Thursday like the last couple of times).
The speakers, in alphabetical order:
Alison Cuff, UCL
The CATH database -- Structural Diversity and the Question of the Fold Continuum
CATH is a hierarchical protein structure classification database. This
talk describes this classification system, and explores whether the
structural divergence in some superfamilies and overlap between fold
groups is posing a serious challenge to the concept of a hierarchical
classification scheme.
Andrew Martin, UCL
SAPTF -- Sequence Analysis Plugin Tool Framework
Sequence Analysis Plugin Tool Framework (SAPTF) is a simple
application framework for developing web sites which perform analysis
of one or more protein or DNA sequences. SAPTF uses a simple XML
configuration file and can easily be integrated with more complex web
site layouts, with all formatting being controlled by CSS. SAPTF uses
AJAX to provide automatic handling of long-running programs which
might make the user believe the web-server is not working, or which
could cause the web-server to time out. The system is designed to call
external programs (plugin tools) which perform the actual sequence
analysis. These can generate HTML or simple plain text. SAPTF can pass
sequence data to the plugin tools on the command line or in files and
is able to manipulate the sequence data (for example, writing it in
FASTA format) before calling the tool.
John Pinney, Imperial
GLASS -- Gene LAyout by Semantic Similarity
In this talk I will present GLASS (Gene LAyout by Semantic
Similarity), a new methodology for data visualization in a
whole-genome context that produces attractive and informative
graphical summaries of genome-scale data sets. GLASS organises the
genome using the concept of the semantic similarity between genes,
producing 2-D genome layouts in the form of Voronoi Treemaps. The maps
created by GLASS can be coloured in various ways to visualize both
discrete and continuous data attached to individual genes. Since genes
with similar properties are grouped together, any biologically
relevant patterns in the data are easily discernable and can be
related in a natural way to the results of statistical analyses.
Running order to be decided on the night.
Location:
Malet Place Engineering Building, Room 1.02, UCL, 6pm
Square C5 on this map: http://www.ucl.ac.uk/maps/ucl-maps/map2_hi_res
(Entrance via the Engineering Front Building where the cafe icon is)
Pub afterwards -- I'm still waiting for the pub to get back to me to
confirm the booking, so I'll let you know the location as soon as.
Please circulate as appropriate -- I'll send a PDF poster too when I
have the pub confirmed.
See you there!
Andrew.