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The EMBO Journal Table of Contents alert Volume 26 Issue 23
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The EMBO Journal Alert  
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 More options Nov 28 2007, 11:45 am
From: "The EMBO Journal Alert" <The_EMBO_Jour...@ealerts.nature.com>
Date: Wed, 28 Nov 2007 11:45:42 -0500 (EST)
Local: Wed, Nov 28 2007 11:45 am
Subject: The EMBO Journal Table of Contents alert Volume 26 Issue 23
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The EMBO Journal
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Table of contents
Volume 26, Number 23 (28 November 2007)
November 2007 Volume 8 Number 11, pp 975-1086
(c) Copyright 2007 by the European Molecular Biology Organization Now available at www.emboreports.org

Visit EMBO reports online to browse the content of the current issue, including Editorial, Science & society, Reviews and Scientific reports. To purchase a subscription, please visit www.nature.com/embor/subscription_info.html.
In this issue...
Constitutive mTOR activation in TSC mutants sensitizes cells to energy starvation and genomic damage via p53
The manuscript by Lee et al. describes an interesting and detailed analysis of the relationships between cell growth and stress response. The authors report that constitutive mTOR activation in cells lacking TSC1 or TSC2 increases the sensitivity to nutrient starvation or DNA damage presumably by TOR-mediated amplification of p53 translation.
ERK activation causes epilepsy by stimulating NMDA receptor activity
Based on conditional brain-specific expression of a constitutively active form of MEK1 Axel Behrens and colleagues report on a novel link between MAP kinase signalling, Eph/Ephrin and NMDA receptor signalling in the context of epilepsy.
 Articles top  
A role for cytochrome c and cytochrome c peroxidase in electron shuttling from Erv1.

Deepa V Dabir, Edward P Leverich, Sung-Kun Kim, Frederick D Tsai, Masakazu Hirasawa, David B Knaff and Carla M Koehler

The EMBO Journal (2007) 26, 23, 4801-4811 doi: 10.1038/sj.emboj.7601909
| Abstract | Full text | Supplementary Information |

Published online: 1 November 2007

Subject Categories: Membranes & Transport | Proteins
Constitutive mTOR activation in TSC mutants sensitizes cells to energy starvation and genomic damage via p53.

Chung-Han Lee, Ken Inoki, Magdalena Karbowniczek, Emmanuel Petroulakis, Nahum Sonenberg, Elizabeth Petri Henske and Kun-Liang Guan

The EMBO Journal (2007) 26, 23, 4812-4823 doi: 10.1038/sj.emboj.7601900
| Abstract | Full text | Supplementary Information |

Published online: 25 October 2007

Subject Categories: Signal Transduction | Differentiation & Death
Yeast PAS kinase coordinates glucose partitioning in response to metabolic and cell integrity signaling.

Julianne H Grose, Tammy L Smith, Hana Sabic and Jared Rutter

The EMBO Journal (2007) 26, 23, 4824-4830 doi: 10.1038/sj.emboj.7601914
| Abstract | Full text | Supplementary Information |

Published online: 8 November 2007

Subject Categories: Signal Transduction | Cellular Metabolism
RIP140 directs histone and DNA methylation to silence Ucp1 expression in white adipocytes.

Evangelos Kiskinis, Magnus Hallberg, Mark Christian, Martina Olofsson, Stephen M Dilworth, Roger White and Malcolm G Parker

The EMBO Journal (2007) 26, 23, 4831-4840 doi: 10.1038/sj.emboj.7601908
| Abstract | Full text | Supplementary Information |

Published online: 1 November 2007

Subject Categories: Chromatin & Transcription | Cellular Metabolism
A cell cycle regulatory network controlling NF-kappaB subunit activity and function.

Benjamin Barré and Neil D Perkins

The EMBO Journal (2007) 26, 23, 4841-4855 doi: 10.1038/sj.emboj.7601899
| Abstract | Full text | Supplementary Information |

Published online: 25 October 2007

Subject Categories: Chromatin & Transcription | Cell Cycle
Multifunctional class I transcription in Trypanosoma brucei depends on a novel protein complex.

Jens Brandenburg, Bernd Schimanski, Everson Nogoceke, Tu N Nguyen, Júlio C Padovan, Brian T Chait, George A M Cross and Arthur Günzl

The EMBO Journal (2007) 26, 23, 4856-4866 doi: 10.1038/sj.emboj.7601905
| Abstract | Full text | Supplementary Information |

Published online: 1 November 2007

Subject Categories: Chromatin & Transcription | Microbiology & Pathogens
Protein requirements for sister telomere association in human cells.

Silvia Canudas, Benjamin R Houghtaling, Ju Youn Kim, Jasmin N Dynek, William G Chang and Susan Smith

The EMBO Journal (2007) 26, 23, 4867-4878 doi: 10.1038/sj.emboj.7601903
| Abstract | Full text | Supplementary Information |

Published online: 25 October 2007

Subject Categories: Genome Stability & Dynamics
Age-dependent requirement of AKAP150-anchored PKA and GluR2-lacking AMPA receptors in LTP.

Yuan Lu, Margaret Allen, Amy R Halt, Michael Weisenhaus, Robert F Dallapiazza, Duane D Hall, Yuriy M Usachev, G Stanley McKnight and Johannes W Hell

The EMBO Journal (2007) 26, 23, 4879-4890 doi: 10.1038/sj.emboj.7601884
| Abstract | Full text | Supplementary Information |

Published online: 1 November 2007

Subject Categories: Signal Transduction | Neuroscience
ERK activation causes epilepsy by stimulating NMDA receptor activity.

Abdolrahman S Nateri, Gennadij Raivich, Christine Gebhardt, Clive Da Costa, Heike Naumann, Martin Vreugdenhil, Milan Makwana, Sebastian Brandner, Ralf H Adams, John G R Jefferys, Oliver Kann and Axel Behrens

The EMBO Journal (2007) 26, 23, 4891-4901 doi: 10.1038/sj.emboj.7601911
| Abstract | Full text | Supplementary Information |

Published online: 1 November 2007

Subject Categories: Neuroscience | Molecular Biology of Disease
Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding.

Brent A Appleton, Ping Wu, Janice Maloney, JianPing Yin, Wei-Ching Liang, Scott Stawicki, Kyle Mortara, Krista K Bowman, J Michael Elliott, William Desmarais, J Fernando Bazan, Anil Bagri, Marc Tessier-Lavigne, Alexander W Koch, Yan Wu, Ryan J Watts and Christian Wiesmann

The EMBO Journal (2007) 26, 23, 4902-4912 doi: 10.1038/sj.emboj.7601906
| Abstract | Full text | Supplementary Information |

Published online: 8 November 2007

Subject Categories: Signal Transduction | Structural Biology
Structural insights into the mechanism and evolution of the vaccinia virus mRNA cap N7 methyl-transferase.

Marcos De la Peńa, Otto J P Kyrieleis and Stephen Cusack

The EMBO Journal (2007) 26, 23, 4913-4925 doi: 10.1038/sj.emboj.7601912
| Abstract | Full text | Supplementary Information |

Published online: 8 November 2007

Subject Categories: RNA | Structural Biology
Identification, structure and mode of action of a new regulator of the Helicobacter pylori HP0525 ATPase.

Stephen Hare, Wolfgang Fischer, Robert Williams, Laurent Terradot, Richard Bayliss, Rainer Haas and Gabriel Waksman

The EMBO Journal (2007) 26, 23, 4926-4934 doi: 10.1038/sj.emboj.7601904
| Abstract | Full text | Supplementary Information |

Published online: 1 November 2007

Subject Categories: Microbiology & Pathogens | Structural Biology

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