> Developers are finding it increasingly difficult to scale disk-based systems to meet the needs of large-scale Web applications. Many people have proposed new approaches to disk-based storage as a solution to this problem; others have suggested replacing disks with flash memory devices.
> In contrast, we believe that the solution is to shift the primary locus of online data from disk to random access memory, with disk relegated to a backup/archival role ... [With] all data ... in DRAM ... [we] can provide 100-1000x lower latency than disk-based systems and 100-1000x greater throughput .... [while] eliminating many of the scalability issues that sap developer productivity today.
http://glinden.blogspot.com/2009/11/put-that-database-in-memory.html
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gwern