If you want a slightly weaker prescription, change just the first
numbers for each eye. Don't change the other numbers. For example,
your "let's say" of
right: -450 -125 95
left: -350 -75 75
corrects all but 1/2 diopter of spherical correction. It should give
you perfect vision for distances up to 2 meters, and a bit of blur
beyond that. You might pass a driver's test with them, but I wouldn't
advise driving with them. I definitely wouldn't suggest them for
movies or spectator sports, but they could be an excellent choice in
many indoor settings (home, work, shopping). These will also let you
focus a bit closer than you can with the full prescription, but
there's a pretty narrow age range where the advantage of 1/2 diopter
on close vision is likely to make a difference. If you're young
enough, you can focus close with the full prescription, and by the
time you're 45 or 50, you need reading glasses or bifocals - 1/2
diopter isn't likely to help too much in typical situations.
The second and third numbers for each eye are corrections for
astigmatism. If you don't fully correct the astigmatism, you won't see
perfectly at any distance. You need the full astigmatism correction to
counteract the asymmetry in your eyes. Without the full correction,
straight lines in some directions will be blurry and straight lines in
other directions will be crisp. The astigmatism correction works at
any distance and with or without correction for your nearsightedness.
Steve