If you could make a nanofluidic 'tunnel' out of DNA origami that when
washed over an open microfluidic channel, stuck into a certain cut-out
section and was sealed around the edges... I think you'd have a cheap
source of nanofluidic reaction centers for something like
single-molecule DNA synthesis, which maybe could be measured with
capacitance or UV Raman spectroscopy to feedback info about whether
extension occurred or not.
--
Nathan McCorkle
Rochester Institute of Technology
College of Science, Biotechnology/Bioinformatics