would you "stemsave" ?

[CrazyCarl]

Good morning all!

So at the recommendation of Mr. bishop I've posted here regarding a
company called "stemsave"

http://www.stemsave.com/

I'm having my wisdom teeth yanked. On hearing about this company I
went from hesitant, to wanting more pulled.

SO, the question:

Is this practice legitimate? Can I expect down the road in 20 years to
say .. "HEYYyy i need a heart valve rebuilt"

.. No problem! I've got pluripotent stemcells under cryo!

True.. or False?

-Carl

[Bryan Bishop]

On Sat, May 14, 2011 at 10:34 AM, Carl Crott wrote:

So at the recommendation of Mr. bishop I've posted here regarding a
company called "stemsave"

I know there are certain services that do this for stem cells, eggs, sperm, and a variety of other tissues. But I don't have any experience with them. I think that your insurance company might know something, if you call up and ask-- but this is a last-resort, I'm fairly sure there should be someone around here that has experience with stem cell banking.

- Bryan
http://heybryan.org/
1 512 203 0507

[Reason]

Stem cell banking just doesn't seem terribly logical at this time for
someone who isn't suffering from a stem-cell-consuming condition that will
eat all their stem cells in just a few short years. In all the scenarios
under which you're stashing away cells for decades ahead, it looks to me
like the advance of stem cell science will obsolete banking over that time
frame by discovering ways to produce pristine cells of any type as needed
from your adult tissues and cell populations.

e.g. the fact that you can do this even today seems promising:

http://www.fightaging.org/archives/2010/12/mitochondrial-rejuvenation-via-in
duced-pluripotency-techniques.php

And there's this:

http://www.fightaging.org/archives/2010/11/good-news-on-aged-stem-cells.php

"Regardless of the gender or age of the patient, or of diabetes, we were
able to isolate in all of them a pool of functional cardiac stem cells that
we can potentially use to rescue the decompensated human heart."

Reason

[Cathal Garvey]

I'm of this line of thinking. By the time a plausible therapy with stem cells becomes mainstream, so will the technology to create iPS's from almost anyone.

In fact, I'm pretty certain advances in iPS technology will yield the first reasonable stem cell therapies; ESCs, requiring cloning, extraction and propagation, will always require expert labour for each individual patient, whereas it's plausible that iPS could be developed into an injection-based therapy where cells are mobilised from their homes in-situ into the bloodstream.

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[Jordan Miller]

iPS is probably the future. But even without iPS (which requires new genetic information being put into cells), lots of people are working with the large number of stem cells naturally found in adult human bone marrow.

Everyone has bone marrow stem cells, no matter how old (you just have fewer as you age).

Bone Marrow-derived stem cells are not as pluripotent as some other cells, but they are your cells so there is no risk of immune rejection. And people have some very clever tricks for "expanding" them (growing them into larger cell numbers without losing their pluripotency).

The thought also is a lot of the umbilical cord blood being saved after a successful birth is very close to human ES cell quality which may have applications in other adults with minimal immune rejection.

There's so much potential in this field, and so much being learned every day, the future is very bright indeed.

jordan

[CrazyCarl]

@reason .. is this a practice that i could walk into my doctors office
and get today? ( btw the link was broken )



are stem cells extracted from wisdom teeth legitimately pluripotent?

how consistent is the induced pluripotency... i mean is there a better
chance that these existing pluripotent cells would work ( for body
repair )

I think the answer i was after is " yes these are pluripotent cells ..
and they can be used to fix you" so ill probably spend the $600

-Carl

[Reason]

> -----Original Message-----

> From: diy...@googlegroups.com [mailto:diy...@googlegroups.com] On

> Behalf Of CrazyCarl

> Sent: Saturday, May 14, 2011 10:33 AM

> To: DIYbio

> Subject: Re: would you "stemsave" ?

>

> @reason .. is this a practice that i could walk into my doctors office

> and get today?

As a general rule, next to nothing published at Fight Aging! falls into that category. That's one of things I'd like to change with the Vegas Group initiative; cut down the 15 year regulatory wait for anything to emerge to something that's more like the timeline seen in the computing hardware industry.

>( btw the link was broken )

Link wrapping in email is the bane of my life. It's one of those things, like failing at VCR programming, that is a measure of one's failing grip on youth.

Reason

[Gavin Scott]

Still a few details to work out:

"In an unexpected setback to efforts to harness a promising new type of stem cell to treat diseases, researchers reported on Friday that tissues made from those stem cells might be rejected by a patient’s immune system — even though the tissues would be derived from the same patient."

http://www.nytimes.com/2011/05/14/science/14stem.html

G.

[CoryG]

My dentist looked at me like I was nuts when I asked if I could keep
my wisdom teeth or if he knew of a place that could keep them on ice
for future stem cell use. Didn't let me keep the wisdom teeth.

[Jordan Miller]

wow nice find! I hadn't seen that yet.

but on the plus side, people have been taking adult cells and growing them up and re-implanting them in humans with no immune rejection already, so this is perhaps another vote for bone marrow-derived stem cells which are not genetically modified before being re-implanted.

jordan