TurboGears - join
Discussion about the TurboGears front-to-back web development megaframework.
Medium activity, 3644 members

pylons-discuss - join
Pylons is a Python Web Framework aimed at making development, distribution, and deployment faster and easier.
Low activity, 1949 members

Django users - join
Discussion group for Django users. Django is a high-level Python Web framework (djangoproject.com).
High activity, 15441 members