Dopamine, working memory, and training induced plasticity: Implications for developmental research.
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XFMQ902SF
Feb 12, 2012, 1:30:14 AM2/12/12
to Dual N-Back, Brain Training & Intelligence
By Söderqvist, Stina;Bergman Nutley, Sissela;Peyrard-Janvid,
Myriam;Matsson, Hans;Humphreys, Keith;Kere, Juha;Klingberg, Torkel
Developmental Psychology, Nov 21 , 2011, No Pagination Specified.
Abstract
Cognitive deficits and particularly deficits in working memory (WM)
capacity are common features in neuropsychiatric disorders.
Understanding the underlying mechanisms through which WM capacity can
be improved is therefore of great importance. Several lines of
research indicate that dopamine plays an important role not only in WM
function but also for improving WM capacity. For example,
pharmacological interventions acting on the dopaminergic system, such
as methylphenidate, improve WM performance. In addition, behavioral
interventions for improving WM performance in the form of intensive
computerized training have recently been associated with changes in
dopamine receptor density. These two different means of improving WM
performance—pharmacological and behavioral—are thus associated with
similar biological mechanisms in the brain involving dopaminergic
systems. This article reviews some of the evidence for the role of
dopamine in WM functioning, in particular concerning the link to WM
development and cognitive plasticity. Novel data are presented showing
that variation in the dopamine transporter gene (DAT1) influences
improvements in WM and fluid intelligence in preschool-age children
following cognitive training. Our results emphasize the importance of
the role of dopamine in determining cognitive plasticity. (PsycINFO
Database Record (c) 2011 APA, all rights reserved)
http://psycnet.apa.org/index.cfm?fa=buy.optionToBuy&id=2011-26494-001
Myriam;Matsson, Hans;Humphreys, Keith;Kere, Juha;Klingberg, Torkel
Developmental Psychology, Nov 21 , 2011, No Pagination Specified.
Abstract
Cognitive deficits and particularly deficits in working memory (WM)
capacity are common features in neuropsychiatric disorders.
Understanding the underlying mechanisms through which WM capacity can
be improved is therefore of great importance. Several lines of
research indicate that dopamine plays an important role not only in WM
function but also for improving WM capacity. For example,
pharmacological interventions acting on the dopaminergic system, such
as methylphenidate, improve WM performance. In addition, behavioral
interventions for improving WM performance in the form of intensive
computerized training have recently been associated with changes in
dopamine receptor density. These two different means of improving WM
performance—pharmacological and behavioral—are thus associated with
similar biological mechanisms in the brain involving dopaminergic
systems. This article reviews some of the evidence for the role of
dopamine in WM functioning, in particular concerning the link to WM
development and cognitive plasticity. Novel data are presented showing
that variation in the dopamine transporter gene (DAT1) influences
improvements in WM and fluid intelligence in preschool-age children
following cognitive training. Our results emphasize the importance of
the role of dopamine in determining cognitive plasticity. (PsycINFO
Database Record (c) 2011 APA, all rights reserved)
http://psycnet.apa.org/index.cfm?fa=buy.optionToBuy&id=2011-26494-001
XFMQ902SF
Feb 14, 2012, 2:21:56 PM2/14/12
to Dual N-Back, Brain Training & Intelligence
Gwern Branwen
Feb 23, 2012, 6:31:40 AM2/23/12
to brain-t...@googlegroups.com
On Tue, Feb 14, 2012 at 2:21 PM, XFMQ902SF <kei...@aol.com> wrote:
> http://tk8nj5xn8a.scholar.serialssolutions.com/?sid=google&auinit=S&aulast=S%C3%B6derqvist&atitle=Dopamine,+working+memory,+and+training+induced+plasticity:+Implications+for+developmental+research.&id=doi:10.1037/a0026179
> http://tk8nj5xn8a.scholar.serialssolutions.com/?sid=google&auinit=S&aulast=S%C3%B6derqvist&atitle=Dopamine,+working+memory,+and+training+induced+plasticity:+Implications+for+developmental+research.&id=doi:10.1037/a0026179
I don't think that link works for anyone but you.
Try http://dl.dropbox.com/u/5317066/2011-soderqvist.pdf
--
gwern
http://www.gwern.net
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