Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute
Department of Biostatistics, Harvard School of Public Health
Evolution of a Cancer Genome
Cancer emerges due to an evolutionary process in somatic tissue. The fundamental laws of evolution can best be formulated as exact mathematical equations.
Therefore, the process of cancer initiation and progression is amenable to mathematical investigation. Current areas of research of the lab include cancer stem cells, evolution of drug resistance, and the dynamics of metastasis formation. In this talk I will
introduce two examples of the application of evolutionary theory to cancer genomics and treatment