Drug-resistant swine flu hits UK

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Pastor Dale Morgan

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Nov 20, 2009, 8:38:36 PM11/20/09
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*Plagues, Pestilences and Diseases

Drug-resistant swine flu hits UK *

By Fergus Walsh
Health correspondent, BBC News


Health officials say a Tamiflu-resistant strain of swine flu has spread
between hospital patients.

Five patients on a unit treating people with severe underlying health
conditions at the University Hospital of Wales, Cardiff, were infected.

Three appear to have acquired the infection in hospital.

They are thought to be the first confirmed cases of person-to-person
transmission of a Tamiflu-resistant strain in the world.

There have been several dozen reports around the world of people
developing resistance to Tamiflu while taking the drug - but they have
not passed on the strain to others.

Just one possible cases of person-to-person transmission of a resistant
strain has been recorded - between two people at a US summer camp - and
this has never been confirmed.

Two of the University Hospital Wales patients have recovered and have
been discharged from hospital, one is in critical care and two are being
treated on the ward.

The health officials stressed there was no risk to anyone else.

They said tests were being carried out to confirm exactly what happened.

The UK has bought enough doses of Tamiflu, which can shorten the
duration of swine flu and reduce the risk of complications, for half the
population.

Serious concern

So any spread of a Tamiflu-resistant strain of the illness is a serious
public health concern.

The H1N1 virus has been remarkably stable since it emerged in April, but
virologists had been half expecting new resistant strains to emerge.

Dr Roland Salmon, director of the National Public Health Service for
Wale's Communicable Disease Surveillance Centre, said: "The emergence of
influenza A viruses that are resistant to Tamiflu is not unexpected in
patients with serious underlying conditions and suppressed immune
systems, who still test positive for the virus despite treatment.

"In this case, the resistant strain of swine flu does not appear to be
any more severe than the swine flu virus that has been circulating since
April."

Dr Tony Jewell, Chief Medical Officer for Wales, said: "We know that
people with suppressed immune systems are more susceptible to the swine
flu virus, which is why they are a priority group under the first phase
of the vaccination programme in Wales which is progressing at pace.

"We have stringent processes in place for monitoring for antiviral
resistance in the UK so that we can spot resistance early and the causes
can be investigated and the cases managed.

"Identifying these cases shows that our systems are working so patients
should be reassured.

"Treatment with Tamiflu is still appropriate for swine flu and people
should continue to take Tamiflu when they are prescribed it.

"It's also important that good hygiene practices are followed to further
prevent the spread of the virus."

Professor Peter Openshaw, a respiratory physician at Imperial College
London, said of the spread: "It's not surprising that this has happened,
indeed it has always been anticipated".

Dr Ronald Cutler, deputy director of biomedical science at Queen Mary,
University of London, said: "Shortening the time taken to produce new
vaccines and improving the methods to control and treat the disease
while vaccines are being made would be a way forward".

On Thursday it was announced that more than three million healthy
children under five across the UK will be offered the swine flu jab.

Figures released on Thursday showed an estimated 53,000 new cases of
swine flu in England in the last week, down from 64,000 in the week before.

In Scotland, the figure was 21,200, down from about 21,500 in the
previous seven days.

The rate of flu-like illnesses diagnosed by GPs in Wales dropped to 36
cases for every 100,000 people from 65.8 the previous week.

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