a question about FIRMA score

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camelbbs

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Jan 5, 2010, 10:47:05 AM1/5/10
to aroma.affymetrix
HI,
I found the FIRMA scores are all >0, so what do you mean the
positive or negative? and i am not very understand this sentence "it
seems logical to find FIRMA scores that are different b/w your 2+
groups". That if there are several samples in each group, how to deal
with it?
Thanks,
Jiang

camelbbs

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Jan 7, 2010, 10:53:23 AM1/7/10
to aroma.affymetrix
Hi,
can anyone help?
Jiang

Mark Robinson

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Jan 11, 2010, 12:01:47 AM1/11/10
to aroma-af...@googlegroups.com
Hi Jiang.

You need to take the log2 of the residuals. CEL files store only
positive numbers.

This question has been answered many times. For starters, have a look
at:
http://www.mail-archive.com/aroma-af...@googlegroups.com/msg01015.html

Cheers,
Mark

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------------------------------
Mark Robinson, PhD (Melb)
Epigenetics Laboratory, Garvan
Bioinformatics Division, WEHI
e: m.rob...@garvan.org.au
e: mrob...@wehi.edu.au
p: +61 (0)3 9345 2628
f: +61 (0)3 9347 0852
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