Batch normalization

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joshy

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Nov 24, 2008, 10:04:20 PM11/24/08

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Hi
I would like to know the following.

If I add a new set of CEL files to the batch of CEL files I have
already normalized, do I need to renormalize all of them together once
agian (as a single batch)
Thanks in advance

Joshy

Henrik Bengtsson

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Nov 24, 2008, 10:22:52 PM11/24/08

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Depends on normalization method? Which one are you using?

/Henrik

joshy

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Dec 2, 2008, 3:26:03 AM12/2/08

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Hi Henrik

What I am doing is the following

AllelicCrosstalkCalibration
FragmentLengthNormalization

This is on a set of affy SNP 6.0 CEL files.
I have to add few more CEL files to the dataset. Do I have to
renormalize all of thme once more.

Thanks
Joshy