Probably not. The first one didn't make enough money for a second, so
they're unlikely to change their mind.
The Avengers was so big because it was a sequel to "Iron Man 2", "The
Incredible Hulk", "Thor" & "Captain America: First Avenger", not
because it was by Joss Whedon.
Whedon will be able to get more money for new projects, though.
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