eve
...@rocketmail.com (evetsm) wrote in message <
news:75b46524.0203131000.f6f1b76@posting.google.com>...
> strangl
...@aol.com (DaveW) wrote in message
> I forgot this.......
> The latest info from published research : visceral adipose tissue ie
> triglycerides around the middle is the cause of insulin resistance.
> Or in street terms, scarfing down excess carbs ,stored as fat from
> insulin converted carbs/glucose, gets you a big belly and makes you
> sick.
Well, well, well......it smells like a skunk, it could well be a
skunk.
Dislipidemia and oxidative stress in mild and in severe psoriasis as a
risk for cardiovascular disease.
Rocha-Pereira P, Santos-Silva A, Rebelo I, Figueiredo A, Quintanilha
A, Teixeira F.
Departamento de Quimica da Universidade da Beira Interior, Rua Marques
d'Avila e Bolama, 6200 Covilha, Portugal. petr...@ciunix.ubi.pt
Psoriasis is a common chronic and recurrent inflammatory skin disorder
that has been associated with oxidative stress, abnormal plasma lipid
metabolism and with high frequency of cardiovascular events. This
prevalence seems to be related to the severity of psoriasis, as it
occurs more frequently in patients presenting large areas of the body
affected with psoriasis lesions. The aim of our work was to evaluate
the development of oxidative stress and of dislipidemia in psoriasis,
and to look for a correlation between their levels and worsening of
psoriasis. We evaluated lipid profile, total antioxidant capacity,
antioxidant vitamins A and E, and lipoperoxidation products. The study
was performed in controls and in patients presenting mild and severe
psoriasis. *****!!!!!Patients presented risk changes in lipid profile
(a rise in cholesterol (P<0.01), triglycerides (P<0.001), low density
lipoprotein cholesterol (P<0.01), very low density lipoprotein
cholesterol (P<0.01), apolipoprotein B (P<0.001) and lipoprotein(a)
(P<0.001); and a reduction in high density lipoprotein cholesterol
(P<0.001)), a rise in lipoperoxidation products (P<0.001) !!!!!!****
(LOOKS LIKE SYNDROME X ?) and a reduction in total antioxidant
capacity (P<0.001) and in antioxidant vitamins A (P<0.001) and E
(P<0.05). Moreover, we found that the worsening of psoriasis was
associated with the enhancement of oxidative stress and of the lipid
risk changes. Our data suggest that psoriasis patients must be
considered as a group at risk for cardiovascular disease and that this
risk seems to be higher in severe psoriasis. In addition, a possible
benefit of an enriched diet or of a supplement of vitamins A and E in
psoriasis patients should be further studied.
