Orv Hetil. 2000 Apr 23;141(17):915-7.
[Role of bile acids and endotoxins in the pathogenesis and therapy of
psoriasis]
[Article in Hungarian]
Gyurcsovics K, Bertok L.
Petz Aladar Megyei Korhaz, Gyor.
The authors demonstrated significant curative effect of bile acids
(Suprachol; Acidum dehydrocholicum) in 551 psoriatic patients. The
clinical efficiancy was evaluated by means of PASI-score (Psoriasis Area
Severity Index). During this treatment (1-8 weeks) 434 patients (78.8
per cent) became asymptomatic. However, the traditional therapy resulted
in 62 patients (24.9 per cent) of 249 sick persons a recovery (p <
0.05). In acute form of psoriasis (184 patients) this curative effect of
bile acids was elevated (95.1 per cent). Two years later 319 patients
(57.9 per cent) of bile treated 551 people were asymptomatic in contrast
with 15 people (6.0 per cent) of 249 traditional treated patients (p <
0.05). In same time among the patients which were treated in acute form
of psoriasis 10 (7.2 per cent) of 139 controls and 147 (79.9 per cent)
of 184 bile-treated individuals were asymptomatic (p < 0.01). On the
basis of their clinical observations (digestive disorders, ultrasonical
confirmed gallbladder complaints, etc.) authors supposed that the
deficiency of bile acids and the consecutive endotoxin translocation
might play a role in the pathogenesis of psoriasis. In normal conditions
the bile acids as detergent (physico-chemical defense) can protect the
body against enteral endotoxins while split them to atoxic fragments and
so preventing consecutive cytokin liberation.
--
All the best,
Pete
------------------------------------------------
Home Page: http://users.bigpond.com/lansma
Location: 42°53'S; 147°19'E
It means that the endotoxins (lps) and rogue amino acids that consPire
to
generate psoriasis can be digested via exogenous digestive supplements,
before they become systemic (get digested).
And clear you up some. I've used a ton of them in the past. But why not
eat
a vegetarian diet or simply block the LPS in the colon? My methods btw.
I love the way the Hungarians think in these instances. They just
haven't
made it to my level yet. <G>
Here is their 2000 study,
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9989105
[Bile acids and endotoxins: physico-chemical defense of the body]
Bertok L.
Orszagos Kozegeszsegugyi Kozpont, Orszagos Frederic Joliot-Curie
Sugarbiologiai es Sugaregeszsegugyi Kutato Intezet, Budapest.
The toxic effects of endotoxin--the cell wall component of Gram
negative intestinal bacteria--under experimental conditions can be
induced only when they are administered parenterally. However, in
naturally occurring enteroendotoxemic diseases (e.g. septic and various
shocks, etc.), the endotoxin absorbs from the intestinal tract. The
cause and mode of translocation was unknown.
<sniP>
The authors (Gyurcsovics K, Bertok L.) 2003 study
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14643904
Pathophysiology of psoriasis: coping endotoxins with bile acid therapy.
Gyurcsovics K, Bertok L.
"Petz Aladar" County Hospital, Gyor, Szent Imre u. 41, H-9024, Hungary
The authors have tested the hypothesis that the deficiency of bile
acids and the consequent endotoxin translocation might play a role in
the pathogenesis of psoriasis. Under normal conditions the bile acids
act as detergents (physico-chemical defense) and can protect the body
against enteric endotoxins by splitting them into nontoxic fragments
and thus preventing the consequent release of cytokines [Persp. Biol.
Med. 21 (1977) 70]. A total of 800 psoriasis patients participated in
the study and 551 were treated with oral bile acid (dehydrocholic acid)
supplementation for 1-8 weeks. The efficacy of the treatment was
evaluated clinically and also by means of the Psoriasis Area Severity
Index (PASI score). During this treatment, 434 patients (78.8%) became
asymptomatic. Of 249 psoriatics receiving the conventional therapy,
only 62 (24.9%) showed clinical recovery during the same period of time
(P<0.05). The curative effect of bile acid supplementation was more
pronounced in the acute form of psoriasis (95.1% of the patients became
asymptomatic). Two years later, 319 out of the 551 acute and chronic
psoriasis patients treated with bile acid (57.9%) were asymptomatic,
compared to only 15 out of the 249 patients (6.0%) receiving the
conventional treatment (P<0.05). At the end of the 2-year follow-up,
only 10 out of 139 acute psoriasis patients (7.2%) receiving the
conventional therapy and 147 out of 184 bile acid treated patients
(79.9%) were asymptomatic (P<0.01).To conclude, the results obtained
suggest that psoriasis can be treated with success by oral bile acid
supplementation presumably affecting the microflora and endotoxins
released and their uptake in the gut.
PMID: 14643904
*****
And the 2000 study you cited,
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10827473
Bertok's 2004 study,
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15561510
randall....
If you have your gall bladder removed (as happens to people, including
a relative of mine), from that point on you have to swallow some acid
with your food to get it digested. I gather that's what they do here,
except with people who still have all their organs, but also have
psoriasis. I am violently skeptical about the reported results, you
can get practically the same effect by eating chips and salsa or spicy
Chinese food or whatnot, and this surely would have been noticed by
people over the past ten thousand years or so.
J.
I am going to Hungary for my annual family visit in a few months. I
spoke with my best friend who is a doctor over there. It has now been
arranged with one of the authors of this study that they will see me
while I am there and I will start treatment. My friend said that
medical research is highly regulated, in his 25+ years in practice, he
cannot recall any instances of published studies with questionable
integrity. Apparently, the drug in question is a known over-the-counter
medication, costs approximately the equvivalent of US$4 for 20
pills.I'll be in the position to ask questions from the researchers
through e-mail even before I leave.If any of you wishes to ask specific
questions, please let me know.I will report my results.
M.
I look forward to your report, and hope it works for you!
J.
--
All the best,
Pete
------------------------------------------------
Home Page: http://users.bigpond.com/lansma
Location: 42°53'S; 147°19'E
--
All the best,
Pete
------------------------------------------------
Home Page: http://users.bigpond.com/lansma
Location: 42°53'S; 147°19'E
Dear HP,
Try,
Google the group for one or two threads regarding this.
If it is porcine digestive factors, i would assume you could buy it
on the web. Or possibly direct from Hungary once they resume sales?
randall
So, if I'm reading this correctly, increasing bile acids - Suprachol and
Acidum dehydrocholicum - may be helpful, even curative. Ok, where might
these be obtained or what foods might one consume to increase bile acids
generally?
You mention porcine digestive factors. I have just started taking
digestive enzymes that include porcine. Is that part of the answer?
Thanks.
--
All the best,
Pete
------------------------------------------------
Home Page: http://users.bigpond.com/lansma
Location: 42°53'S; 147°19'E
We read it the same then.
> Ok, where might
> these be obtained or what foods might one consume to increase bile acids
> generally?
>
http://www.google.com/search?hl=en&lr=&q=bile+digestive+aids&btnG=Search
> You mention porcine digestive factors. I have just started taking
> digestive enzymes that include porcine. Is that part of the answer?
>
Ox or porcine bile would seem to be the same to me. If there
is something there that digests LPS more effectively for porcine
bile, it would be significant.
> Thanks.
>
No problem. Now you have me wondering. Lps does alter gut
motility and I have generally shied away from pork.
Oh well nevermind. Let us know how you do. Try both! NOt at the
same time of course.
I have received some preliminary instructions from the doctors in
Hungary. I have decided that I'll try to start treatment ASAP. I hope I
can arrange a trip in the next few weeks. I was told to get a blood
work dome for Folic Acid and B12 levels. I was also directed to
http://www.freeweb.hu/psoriasis/ to read about their theory in general,
and to look at the recommended diatery restrictions in particular. The
original, Hungarian version is a little more detailed than the English
translation, and it warns specifically about the dangers of stimulating
(increasing) bile secretion without first reducing the level of
existing toxicity, because it may trigger a reaction contrary to the
desired result. Michael.
Looks interesting. Are you sure this doctor didn't read my posts and
toss this
thing to-gether? lol
Hope it works for you. And please keep us posted on results. What are
your demographics now? Severity %, age/onset, strep, family involvement
etc.
randall
--
All the best,
Pete
------------------------------------------------
Home Page: http://users.bigpond.com/lansma
Location: 42°53'S; 147°19'E
Now this is all very interesting to me. Thanks very much for the link
Michael.
What's with the folic acid and B12 levels? I've been supplementing those
two compounds with B6 for quite a while to lower homocysteine (not that
my levels are high). Is the suggestion that levels might be too high,
too low, indicative of something good, or something bad in those with P?
I have been taking 50 mg /d B6, 500 mg/d B12, and 5 mg/d folic acid, and
would run away with pleasure at taking them if they may be making my P
worse.
The macromedia presentation is simple but excellently demonstrates their
theory graphically. I've have remained ignorant of what exacerbates my P
but since joining this group and doing some independent reading I just
discovered I should not eat spicy curries. Yesterday I made a Thai fish
red curry and threw in a 1.5 tablespoons of turmeric for good measure.
It was so scrumdiddleyumshous that I ate it for breakfast, lunch, and
dinner (I am low-carbing also). My skin really flared up last night and
I put it down to the turmeric for some reason. But in watching the flash
presentation is dawned on me that more likely it was the hot spices
namely the nightshade chilli. It sits well with black pepper being a
trigger for others also.
Did that patch out?
> I can't recall strep
> involvement at the time. Incidentally, the doctor asked me the same
> question yesterday, along with if I recalled having any infected teeth,
> or being physically disgusted with something at the time.
I guess we all look for the trigger to satisfy ourselves some how.
Like curiousity really killed the psoriatic. Or his P at the
least.
We only wish. <sigh>
What about antibiotics before onset? Any of those?
Sounds like the P tide moved in and rose slowly in your case.
> The symptoms
> skipped a generation in my case. Neither my Dad, nor any of his 5
> siblings had psoriasis, but 3 of my female cousins on that side have
> it, although, in a much milder form, as I understand. I am on a low
> carb regimen for the past 2 1/2 years, but moderating meat consumption
> as much as I can. I am a pack-a-day smoker and I do not drink alcohol
> at all. My diet change did not seem to effect my disease. My coverage
> today is a good 40-45%. Legs, thighs, lower back, some torso, arms up
> to elbows, scalp, all fingers and toes. Steadily progressed, never had
> a remission. That will change soon if you and those crafty Hungarians
> are right. Michael
You would seem to be the perfect test bed for what they offer.
If LPS is the P pest that Bertok thinks it is, your his man.
BTW, thanks again for the link. It was freaky to say the least.
The page with LPS (does not equal) psoriasis something and then
it goes on to say it's the culprit was a hoot. I even went back
and looked at the hungarian pages.
I'm getting sorta excited. Can I go too? <g>
At the very least, maybe i'll pop some pig bile caPs.
That opens a realm of possibilities for what gets digested.
Er, served for suPPer, i mean.
randall can we say baby backs! Or hungarian goulash perhaPs?
Your the other perfect test bed as well, being a low carb-er and having
P. Go get some ox or porcine digestive aids and let us know.
There's no reason you can't find some in your own backyard.
Lets see. Oh, i see where your at. Duh!
Try a few from this list,
http://www.nspaust.com.au/states/tas1az.html
One of them is sure to have something.
randall....
Randall,
General health food stores would not sell this kinda stuff, anyway its
much cheaper on the net.
I have located a couple of local products that might fit the bill. What
do you reckon about these two?
1. Top item here: http://www.ethicalnutrients.com.au/content/?id=16
2.
http://www.thexton.com.au/product/Essential__Enzymes__120__Caps/category_id/-1
There is no shortage of products that claim to 'stimulate bile acids,'
from dandelion through to various 'digestive bitters.' It would be
decidedly convenient for some entrepreneur to crystallise the essential
components from all of these into a megabile tablet.
I stumbled on a little snippet of information that furthered my
understanding of what solutions there may be for this Bile acid and
endotoxin problem. In particular the utility of adding hydrochloric acid
(betaine HCl) and porcine pepsin to the diet.
The reference that got me started is here:
http://www.newtreatments.org/doc.php/WisdomExperience/182
An article that addresses the clinical implications of HCl
supplementation is here:
http://www.thorne.com/altmedrev/fulltext/hcl.html
There is a table in this article that summarises investigations of
stomach acidity in 400 patients with skin disorders and suspected B
vitamin deficiency. This research was done in 1945! The most compelling
data in this table is that provided for patients with psoriasis. 56% of
cases showed achlorhydria, 33% showed hypochlorhydria, and only 11%
showed normal levels of HCl.
The shortcut to the table is here:
http://www.thorne.com/altmedrev/fulltext/hcl-tab4.jpg
The other line of enquiry suggested in the initial article is the
relevance of a low-carb diet, more specifically in this instance a
selective carbohydrate diet, which appears helpful for patients with
Crohn’s Disease and Ulcerative Colitis. Apparently problems have been
found in metabolising Disaccharides and polysaccharides:
http://www.newtreatments.org/scdiet.php.
I am following a low-carb diet that actually seems more restrictive than
the SCD, but I am considerably more impressed by what I am learning
about ways to correct the Bile acid and endotoxin problem.
And proposed the use of these DA's, in posts 19 and 20 of this thread,
as a way
to digest the high protein diet he's on and stop the LPS from gaining
systemic entrance,
http://www.ethicalnutrients.com.au/content/?id=16
http://www.thexton.com.au/product/Essential__Enzymes__120__Caps/category_id/-1
http://www.thexton.com.au/product.php?product_id=1433
> Ok, I think I am getting somewhere with all of this.
>
I'll say! When you do your homework. Your cookin!
>
>
> I stumbled on a little snippet of information that furthered my
> understanding of what solutions there may be for this Bile acid and
> endotoxin problem. In particular the utility of adding hydrochloric acid
> (betaine HCl) and porcine pepsin to the diet.
>
>
Gosh! And you didn't even have to go to Budapest, Hungary
47 30 N 19 5 E
>
> The reference that got me started is here:
> http://www.newtreatments.org/doc.php/WisdomExperience/182
>
>
>
> An article that addresses the clinical implications of HCl
> supplementation is here:
> http://www.thorne.com/altmedrev/fulltext/hcl.html
>
>
>
> There is a table in this article that summarises investigations of
> stomach acidity in 400 patients with skin disorders and suspected B
> vitamin deficiency. This research was done in 1945! The most compelling
> data in this table is that provided for patients with psoriasis. 56% of
> cases showed achlorhydria, 33% showed hypochlorhydria, and only 11%
> showed normal levels of HCl.
>
>
So who prevented this secret from getting out? lol
One of your links actually takes you to Steve's (evetsm) 2000 post
on HCL, made in this grouP!
To bad no one glommed on to his speculations then. Or did they?
Of course I know how he feels. lol
>
> The shortcut to the table is here:
> http://www.thorne.com/altmedrev/fulltext/hcl-tab4.jpg
>
>
>
> The other line of enquiry suggested in the initial article is the
> relevance of a low-carb diet, more specifically in this instance a
> selective carbohydrate diet, which appears helpful for patients with
> Crohn's Disease and Ulcerative Colitis. Apparently problems have been
> found in metabolising Disaccharides and polysaccharides:
> http://www.newtreatments.org/scdiet.php.
>
>
>
> I am following a low-carb diet that actually seems more restrictive than
> the SCD, but I am considerably more impressed by what I am learning
> about ways to correct the Bile acid and endotoxin problem.
>
>
> --
> All the best,
> Pete
>
> ------------------------------------------------
> Home Page: http://users.bigpond.com/lansma
> Location: 42°53'S; 147°19'E
Thanks Pete. While much of this makes sense, i'm awaiting your
personal trials. If we could pack you up with Michael and send
you to Dr. Bertok the controls on this test/quest may be better.
But for practicality i'll take you at your word.
When do you start?
And have you removed all lectins besides the obvious?
Good luck,
randall... been there, done that... still like to eat & P<4%!
Hey! That was no accident! Now that I went back and saw it,
it was to me. I want to go.
And since it uses antibiotics first, cruiser may join up.
Thanks for thinking of us. But we will rely on your experiences.
Take good notes so we will know exactly what you've done.
What sPort? Soccer?
randall
Michael, I'd be interested in the translation if you find the time. I
will respond further below.
> Thanks Pete. While much of this makes sense, i'm awaiting your
> personal trials. If we could pack you up with Michael and send
> you to Dr. Bertok the controls on this test/quest may be better.
>
> But for practicality i'll take you at your word.
>
> When do you start?
I have just ordered the HCl supplements. They should arrive in a few
days. Before beginning, I'd like to see Michaels translation of the
Hungarian webpage for a little further info. I am proposing to do a
lengthy colon-cleanse before I embark on supplantation of HCl. Those
products are a day or so away.
> And have you removed all lectins besides the obvious?
"Lectins are carbohydrate binding proteins present in most plants,
especially seeds and tubers like cereals, potatoes, and beans." Thanks
for reminding me about these. I am not consuming too many if any of
these but for different reasons being on a low-carb diet. I did read
about them early on and resolved to give up beans (the remaining lectins
in my diet).
> randall... been there, done that... still like to eat & P<4%!
So, what were your results...what was post helpful in your case?
Thanks. The translation would be good. I'm wondering whether a full and
lengthy colon cleanse might 'suffice' in addition to probiotic
supplementation. There's all sorts of claims made about these products
of course, but I thought I would give it a go anyway
Thanks for the translation, Michael. It is interesting about the lemon
juice as I had definite clearing when I was drinking about 100 ml per
day. I was also on holidays in sunny Queensland at the time, and I put
it down to the latter. I only stopped drinking it because my carbs were
creeping up, but I may reinstate it during my trial.
> late of September. I'll be happy to bring you guys back an 8 weeks'
> supply of the drugs if you'd like. I am even willing to absorb the
> charges in exchange for detailed accounts. (Of course, by now I know
> that it costs less than $7 for the whole shabang. LOL)
> Best regards,
> Michael.
You are too generous. I'll happily pay and for all shipping to Oz.
Thanks a million.
Further instructions will follow soon. Since I definitely won't be able
to travel earlier than September, my doctor friend picked up the
medication from Dr. Gyurcsovics today, and he will FedEx it to me. I'll
start taking it next week. Some practical diet tips and, if I
understand correctly, actual meal plan suggestions will be included in
the written material that he received from the doctor. She included
some additional supplement that will assist me in balancing my body Ph.
It is some powder that you mix in water. If you are too acidic, it
tastes sour, if you are balanced it is neutral, and if you don't have
enough acid it tastes sweet. It must be taken in conjunction with the
bile acid supplement and you adjust your dose accordingly.The standard
dose is 250 mg twice or 3 times a day with meals. The doctor emphasised
the importance of recording every single meal. She brought an example
that they had a stubborn case; this guy kept breaking out and finally
they found that the culprit was a certain liver pate, that he ate at
least once a week and it contained the spice marjoram. So it is also an
individual trial and error thing. Also, for you and I, it will be a
challange to keep the low carb thing going, because high fiber intake
is recommended. I wonder if we can get away with adding psyllium husk
as I have been doing. Any ideas?
Michael
Good idea. And once done, you'll need to re-implant some new flora
and feed it galactose to grow it out.
> before I embark on supplantation of HCl. Those
> products are a day or so away.
>
> > And have you removed all lectins besides the obvious?
>
> "Lectins are carbohydrate binding proteins present in most plants,
> especially seeds and tubers like cereals, potatoes, and beans." Thanks
> for reminding me about these. I am not consuming too many if any of
> these but for different reasons being on a low-carb diet. I did read
> about them early on and resolved to give up beans (the remaining lectins
> in my diet).
>
> > randall... been there, done that... still like to eat & P<4%!
>
> So, what were your results...what was post helpful in your case?
>
With the wholewhey.com program, you do the same basic things. But
don't go back to a high protein diet. Your on a vegetarian regime
and you'll stay clear as long as you do.
Once you go back to meat/eggs and funky fats/lipids you slowly
loose ground. Your able to fight the P battle with using
sweet whey (galactose) everyday to support the good gut critters.
But with your porcine/ox bile tablets (HCL) as suPPort you may pull
it off. Could it be a stereo fat that gets taken out as well as LPS
in this program? I'd suspect the stereo fats are generated in the skin.
Yet your trial here is certainly a variation of the randall's whey
program, but if it can be done, it highlights definite psoriasis
pathways and
their significance.
Keep us posted as to + or - results.
My p news post today is leading me towards a fatty lipid skin post
beyond what was already hastilly posted. Ceramides slow wound healing
and we obiously don't have enough. But why? And what does
endotoxin (LPS) have to do with it? When you read Bertok you wonder
why the rest of the dermatological world missed the LPS boat.
I only hope to show a few connections via a few abstracts.
randall... yeah right! i want the whole taco already.
Very interesting indeed.
> I, it will be a challange to keep the low carb thing going, because
> high fiber intake is recommended. I wonder if we can get away with
> adding psyllium husk as I have been doing. Any ideas?
> Michael
I don't see why not. This is negligible effects on insulin levels. I've
never found low-carbing a problem in that respect - even small amounts
of fibre get me by.
I'm assuming this is about obtaining colon mobility (only) and it would
seem that psyllium husk should suffice.
randall wrote:
> Good idea. And once done, you'll need to re-implant some new flora
> and feed it galactose to grow it out.
I don't get this. I do plan to use some heavy duty probiotics, but
what's the logic of using galactose? I have read that monosaccharides
are ok for the Specific Carbohydrate Diet because they are fully and
quickly absorbed in the small intestine. Is this not however going to
elicit an (anti-low-carb) insulin response? Moreover, I was thinking
that the flora needs to be 'nourished' in the colon not the small
intestine. Perhaps you can shed some light on this?
The other thing is that I have never heard or read of the importance of
nourishing probiotic growth. Perhaps this is because most contemporary
diets are thought to contain sufficient sugars - just not low-carb. And
I'm still left with the confusion of galactose apparently being absorbed
quickly in the small intestine and not making its way to the colon where
presumably the probiotics would need it.
Please set me right!
> But with your porcine/ox bile tablets (HCL) as suPPort you may pull
> it off. Could it be a stereo fat that gets taken out as well as LPS
> in this program? I'd suspect the stereo fats are generated in the
> skin.
Sounds intriguing, but what is a stereo fat?
> Keep us posted as to + or - results.
Will do. I plan to keep an electronic diary of the process. Hopefully
lots of + and little -'s.
Once you implant seeds it's best that they get what they need to hook
in and then thrive.
If your eating meat or drinking alcohol they can't survive long enough
to make a difference.
If your gut is tilted to far to the bad bugs, you have to stop
feeding them and concentrate on what new stuff you put in.
Its no easier to do this then simply clear your P. Both being the
same grail, take the same work.
Think of an infants body. Without teeth they can't screw up the process
unless you feed them putrefactive foods to soon.
Then their colon changes and if they haven't established a good colony
of
flora, they may never.
If you want a *born again colon* you have to duPlicate the same process
the baby goes thru. You need to *breast feed* the colon, so to sPeak.
The good flora, unless enterically coated to go thru acid (stomach) and
alkaline (small intestines) won't make it to the colon and must be
rectally implanted in a prepared colon. After that it needs the sweet
whey to grow out. In three to four weeks you will understand what it
means
to have a killo of new flora in your colon.
read thewholewhey.com site.
> I have read that monosaccharides
> are ok for the Specific Carbohydrate Diet because they are fully and
> quickly absorbed in the small intestine. Is this not however going to
> elicit an (anti-low-carb) insulin response? Moreover, I was thinking
> that the flora needs to be 'nourished' in the colon not the small
> intestine. Perhaps you can shed some light on this?
>
Galactose doesn't digest quickly. Enough to get the job done goes right
on thru. Lactose digests
down to galactose and glucose.
You need to learn how to search the group on these things.
Go to www.deja.com and look how it's preset for the groups.
enter psoriasis and find our group using a few key words. Like your
name + P, will do it.
Then enter *galactose* in the search this group box. Then hit
the post most recent posts first,
http://groups-beta.google.com/group/alt.support.skin-diseases.psoriasis/search?q=galactose&start=0&scoring=d&
You can search anything or anybody and any combo of that. If it's in
the
groups you can find it quickly and easily using good key words.
Good luck.
> The other thing is that I have never heard or read of the importance of
> nourishing probiotic growth.
I'm one of the first to really figure out the importance of being
able to do it and to still cheat/eat and not wiPe out the good
flora.
> Perhaps this is because most contemporary
> diets are thought to contain sufficient sugars - just not low-carb. And
> I'm still left with the confusion of galactose apparently being absorbed
> quickly in the small intestine and not making its way to the colon where
> presumably the probiotics would need it.
>
> Please set me right!
>
Galactose doesn't digest as easily as glucose. It feeds the good gut
buddies.
I'll see if i can find a link,
http://arbl.cvmbs.colostate.edu/hbooks/pathphys/digestion/smallgut/absorb_sugars.html
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=4067776&dopt=Abstract
Understanding lactose problems,
http://www.wiley.com/legacy/college/boyer/0470003790/cutting_edge/lactose_intolerance/lactose_intolerance.htm
As the northern europeans have more P problems the prior link makes
sense DNA
wise. We are so white that some of us (the 2%) are whiter and flakier
then
the rest. lol
> > But with your porcine/ox bile tablets (HCL) as suPPort you may pull
> > it off. Could it be a stereo fat that gets taken out as well as LPS
> > in this program? I'd suspect the stereo fats are generated in the
> > skin.
>
> Sounds intriguing, but what is a stereo fat?
>
> > Keep us posted as to + or - results.
>
> Will do. I plan to keep an electronic diary of the process. Hopefully
> lots of + and little -'s.
>
> --
> All the best,
> Pete
>
Thanks
randall
You'd think that P severity means sepsis in his model. And I think i
know what you mean.
I'll have to think it over.
It seems that we could hold sepsis at bay by taking on water weight.
So, are the actual P plaques compensatory for LPS? Ponder time.
> If
> so, what happens to patients' insides when their scaling is arrested
> with conventional treatments, like steroids?
It's on hold till the rebound damn is broke?
Same as with bilogicals but without the massive flare beyond the
previous
levels?
For the record, i'm not so sure there aren't intermediate (many) steps
between LPS and the plaques and as Bertok's page is so lacking in
scientific
proof whose to say he isn't on that same page. If we are slightly
septic
is the high level of TNF proof positive of that?
For all we know at this point the LPS may only prime the Th1 sideways
tilt
and completely non-allied forces are at work as to the plaques
themselves.
I would still surmise a gene will be discovered or imPlicated. Sooner
rather
then later would be my hoPe.
randall
> Michael
Thanks again Michael for the information.
This doesn't seem too much of a departure from my present diet. I think
I mentioned up the tree somewhere that I had a good degree of clearing
when I was drinking about 150 ml of lemon juice per day (made up with
water and a few Splenda tablets into a very palatable substitute for
just water alone). Apart from the bread, the dietary modification
suggested sound low-carb-ish, which suits me.
Before beginning with your advised approach and increasing lemon and
turmeric that I know work for me I am undergoing a colon-cleanse. My
tablets arrived this week and I've taken my first dose today. This will
last about 4 weeks. Next I will introduce probiotics and inulin for a
few weeks alone and then supplement their use with hydrochloric acid and
pepsin. At that stage I will fire with everything in my armoury -
digestive supplements, lemon juice, dandelion, turmeric, and anything
else I can think of, while still taking the probiotics. I have done some
further research and apart from turmeric being anti-inflammatory, I
think its success may be due to it being a powerful bile stimulant
itself. I plan to keep a good record of progress.
If you find out *anything* else, please keep us posted.
Good luck mate.
--
All the best,
Pete
------------------------------------------------
Ha! I've wondered what in eggs was helping me, and it seemed to be in
the yolk.
> drink hibiscus or hip(?) tea.
Rose hips?
> Always toast your bread.
Why?
J.
Yes. I just found out it was Rose hip tea. As to the bread - if you eat
bread - she just said to toast it. I low carb, so it does not concern
me much. She did not offer any explanations why to toast it though. Any
of you know about the "living flora" sour cream thing. Could it be the
same as Proflora? I can't figure it out. Hungarian is such an intricate
language, sometimes even I am puzzled, and its supposed to be my mother
tongue.Oh, well. The important thing is that the meds are going to
arrive soon, then we'll really see. I am very sceptical by nature, but
somehow I have a strange, unexplainable, very positive feeling about
this. Michael.
Me too.
I Googled and couldn't locate the product but I would say that "living
flora" means proflora. Sour cream is cultured normal cream. I am
assuming it is similar to the production of yoghurt from milk using
friendly bacteria.
--
All the best,
Pete
------------------------------------------------
Pete, if you are doing the bile acid thing, you may want to consider
adding this also.Judging from the ingredients, probably it is
inexpensive to have it made by any local chemist.
I did an inventory on myself. I suppose, as of now,I have a 35-45%
coverage at places as stated somewhere above in this tree. I hope to
report rapid, steady improvement soon.
Michael
Thanks Michael.
Are you still travelling to Hungary? I did a search on OptAcid and came
up blank in this country. I found a few links in Hungary including this
one: http://www.meditop.hu/oldal_eng.swf . I just shot them off an email
regarding sales and postage to Australia. Their website is in English so
my hope is that they can read English as well. Pharmacists are pretty
cagey in this country and I doubt they would make anything for me
without a doctor's prescription. I note from the website that it is an
'over the counter' formula. Also, I think the ingredients you've given
are in Hungarian for searching for them only leads to Hungarian
websites?
Meanwhile, I'm in to day 10 of my cleansing routine. I'm not strictly
sticking to my low-carb regimen, but so far so well.
Michael, that sounds pretty neat. Can I impose upon you to translate
from Latin. There must be something similar in this country, surely. If
I have no luck I will get back to you.
Again thanks Michael. I am still researching and following up some
leads. I started the cleanse on Aug 08 and it takes about a month.
Following that I will do about 4 weeks of probiotic implantation
(Randall has convinced me to try from both ends). Then I'll be ready for
the bile stimulation phase. So, I won't need the OptAcid for 6 or 7
weeks or so. I'm very grateful that you can help me out here.
I'm using a freeware program called KeyNote to collate the massive
amount of research information I have collected so far. I'll give you an
overview of my plan as it stands at this point. I invite your comments:
1. Cleanse - underway using VitaKlenz herbal supplement - 4 weeks
2. Hydrotherapy treatment(s) - 1 week
3. Probiotic implantation - acid-tolerant Acidophilus Bifidus L.
acidophilus and B. animalis capsules and VitaKlenz Recharge probiotic
powder by mouth + rectal implantation of same. These will be taken with
the 'prebiotic' inulin (up to 15 g/day)- 4 weeks
4. Bile treatment - Betaine Hydrochloride and porcine pepsin digestive
formula comprising 1.3 g HCl and 260 mg pepsin 15 min before each meal
in addition to St Mary's Thistle, Dandelion, Turmeric, and artichoke
supplements all of which are bile stimulating and liver protecting. I
may also swallow the cocktail down with lemon juice.
5. One hopes probiotic supplementation and corrective bile production
will resolve the hyperpermeability problem, however, I may then
supplement with L-Glutamine, Quercetin and other flavonoids, fish oil,
etc.
I was not able to find bile products in Australia and it seems that are
banned from sale. I have found some interesting research on HCl
supplementation particularly in relation to P and it seems to hold
promise. I'm not sure whether we have problems with bile production or
bile release or both. I hope that HCl + my bile stimulants will do the
trick with the aid of a better prepared GI tract.
I've been doing so much reading lately that I'm just about fed up and
want to get into the active treatment phase NOW. The cleansing program
seems rewardless and is just taking up time.
Although I'm feeling optimistic, there are a few things that continue to
bother me. Most sources denounce red meat as positively evil, and other
meats not too far behind. The common belief is that one has to go
vegetarian or even vegan to improve one's health. You and I know that's
crap and that low-carbing is healthy but I wonder whether cutting back
on the protein and fat would take a load off the digestive system during
the active phases of treatment. What do you think?
Just when I thought I had it all figured. Alas, back to the drawing
board. <sob>
BTW: Wherever he is, Lewis Carroll would be offended by your misuse of
his noun and your misspelling of it. You'd do well to remedy that, and
your tone, if your intent is to appear authoritative.
--
Pete
Thank you, bj. I will most certainly take you up on your kind offer.
For now, I am taking the bile supplement, and I sure hope it will work
for me. We'll see.
I'll keep you guys informed of my experience.
Best regards.
Michael.