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Effects of nasal irrigations with sulfurous-arsenical-ferruginous thermal water
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asfyso
Apr 28, 2012, 8:48:37 AM4/28/12
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Am J Otolaryngol. 2012 Apr 19. [Epub ahead of print]
Smoking and chronic rhinitis: effects of nasal irrigations with
sulfurous-arsenical-ferruginous thermal water: A prospective,
randomized, double-blind study.
Ottaviano G, Marioni G, Giacomelli L, La Torre FB, Staffieri C,
Marchese-Ragona R, Staffieri A.
Source
Department of Neurosciences, Otolaryngology Section, Padova
University, Padova, Italy.
Abstract
PURPOSE:
Smoking is a self-destructive behavior that is known to induce
remodeling of the lower airways, leading to squamous metaplasia, but
little is known about its effects on the nose and paranasal sinuses.
Nasal irrigations are often mentioned as measures for treating
sinonasal inflammations. The purpose of our study was to compare the
effects of nasal irrigations with sulfurous-arsenical-ferruginous
thermal water or isotonic sodium chloride solution in smokers with
nonallergic chronic rhinosinusitis, based on clinical and olfactory
evidence.
MATERIALS AND METHODS:
The present study was a prospective, randomized, double-blind study
performed in a tertiary academic referral center. Seventy smokers with
nonallergic chronic rhinitis were enrolled. Nasal endoscopy,
rhinomanometry, nasal cytology, and odor threshold measurements were
performed in subjects randomized to daily nasal irrigations with
either thermal water or isotonic sodium chloride solution for 1 month.
RESULTS:
Immediately after the treatment, the thermal water irrigations
revealed a positive pharmacologic action, judging from a tendency
toward lower nasal resistances (P = .07) and larger numbers of
ciliated cells in the patients treated (P = .003). Endoscopic findings
in the thermal water group were still better than in the control group
a further 2 months later (P = .03).
CONCLUSIONS:
Our results indicate that nasal irrigations with thermal water had a
good effect on endoscopic objective signs, nasal resistances, and
epithelial trophism.
Copyright © 2012 Elsevier Inc. All rights reserved.
Smoking and chronic rhinitis: effects of nasal irrigations with
sulfurous-arsenical-ferruginous thermal water: A prospective,
randomized, double-blind study.
Ottaviano G, Marioni G, Giacomelli L, La Torre FB, Staffieri C,
Marchese-Ragona R, Staffieri A.
Source
Department of Neurosciences, Otolaryngology Section, Padova
University, Padova, Italy.
Abstract
PURPOSE:
Smoking is a self-destructive behavior that is known to induce
remodeling of the lower airways, leading to squamous metaplasia, but
little is known about its effects on the nose and paranasal sinuses.
Nasal irrigations are often mentioned as measures for treating
sinonasal inflammations. The purpose of our study was to compare the
effects of nasal irrigations with sulfurous-arsenical-ferruginous
thermal water or isotonic sodium chloride solution in smokers with
nonallergic chronic rhinosinusitis, based on clinical and olfactory
evidence.
MATERIALS AND METHODS:
The present study was a prospective, randomized, double-blind study
performed in a tertiary academic referral center. Seventy smokers with
nonallergic chronic rhinitis were enrolled. Nasal endoscopy,
rhinomanometry, nasal cytology, and odor threshold measurements were
performed in subjects randomized to daily nasal irrigations with
either thermal water or isotonic sodium chloride solution for 1 month.
RESULTS:
Immediately after the treatment, the thermal water irrigations
revealed a positive pharmacologic action, judging from a tendency
toward lower nasal resistances (P = .07) and larger numbers of
ciliated cells in the patients treated (P = .003). Endoscopic findings
in the thermal water group were still better than in the control group
a further 2 months later (P = .03).
CONCLUSIONS:
Our results indicate that nasal irrigations with thermal water had a
good effect on endoscopic objective signs, nasal resistances, and
epithelial trophism.
Copyright © 2012 Elsevier Inc. All rights reserved.
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