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Iron In Multiple Sclerosis

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ironjustice

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Jan 3, 2010, 3:30:53 PM1/3/10
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"We conclude that iron dysregulation may contribute significantly to
MS susceptibility"

I hear alot of .. commotion .. about Dr. Zamboni and his effective
method of multiple sclerosis treatment.
We .. don't .. hear alot of discussion about removal of the iron.
We JUST hear about how .. easy .. Dr. Zamboni's treatment .. is.
The iron ITSELF seems was never addressed.
One might give the analogy of rings in your car.
The rings can be replaced / angioplasty of the veins in the neck ..
BUT .. the iron is never addressed / carbon / gunk IN the engine
itself is not removed.
Sooo .. it may be temporary .. unless one addresses the iron / removes
the iron ?
--------

Analysis of the NRAMP1 gene implicated in iron transport:
association with multiple sclerosis and age effects.
Kotze MJ, de Villiers JN, Rooney RN, Grobbelaar JJ, Mansvelt EP,
Bouwens CS, Carr J, Stander I, du Plessis L
Blood Cells Mol Dis 2001 Jan-Feb; 27(1):44-53.

Multiple sclerosis (MS) is believed to be an autoimmune process
occurring in genetically susceptible individuals after an
appropriate environmental exposure.
We have exploited the homogeneous Afrikaner population of
European ancestry to investigate the likelihood that iron
dysregulation, in association with infectious and/or autoimmune
disease susceptibility, may underlie the MS phenotype in a
subgroup of patients.
The functional Z-DNA forming repeat polymorphism of the
natural resistance-associated macrophage protein-1 (NRAMP1)
gene was analyzed in 104 patients diagnosed with MS and 522
Caucasian controls.
A family-based control group consisting of 32 parental alleles
not transmitted to MS offspring was additionally studied to
exclude the likelihood of population substructures.
Statistically significant differences in allelic distribution
were observed between the patient and control samples drawn from
the same population (P < 0.01).
Evidence is furthermore provided that alleles considered to be
detrimental in relation to autoimmune disease susceptibility may
be maintained in the population as a consequence of improved
survival to reproductive age following infectious disease challenge.
Although it remains to be determined whether the disease phenotype
in MS patients with allele 5 of the NRAMP1 promoter polymorphism
is directly related to dysregulation of iron or modified
susceptibility to viral infection and/or autoimmunity, a combination
of these processes most likely underlies the disease phenotype in
these patients.
In view of the emerging role of polymorphic variants in complex
diseases and minimizing of possible confounding factors in this
association study, we conclude that allelic variation in the NRAMP1
promoter may contribute significantly to MS susceptibility in the
South African Caucasian population.

Blood cells, molecules & diseases. [Blood Cells Mol Dis]


------


Who loves ya.
Tom


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DEAD PEOPLE WALKING
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evilzona

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Jan 4, 2010, 12:25:02 AM1/4/10
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how do you remove the iron?

fer...@paris.com

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Jan 4, 2010, 8:25:45 AM1/4/10
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""We conclude that iron dysregulation may contribute significantly to MS
susceptibility""

Exactly the point I make often, the real question is why a few but not
all who eat the same things with equal amounts of meat and iron etc.
have a failure to regulate the iron levels.

Why does the normal process of iron regulation fail in those few?

As always, iron levels follow the failure for normal regulation, it is
not the cause of it nor of ms as a cause unto itself.

ironjustice

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Jan 6, 2010, 8:01:34 PM1/6/10
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fer...@paris.com

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Jan 7, 2010, 9:03:59 AM1/7/10
to
"We conclude that iron dysregulation may contribute significantly to
MS susceptibility"

"I hear alot of .. commotion .. about Dr. Zamboni and his effective
method of multiple sclerosis treatment. We .. don't .. hear alot of
discussion about removal of the iron. We JUST hear about how .. easy ..
Dr. Zamboni's treatment .. is. The iron ITSELF seems was never
addressed."


We don't need to consult anyone else, we can use the bit you provided
above. It is not the mere presense of iron, it is always there in every
cell, it is when the regulation system of iron becomes faulty that the
disorder seems to appear.

In other words, the old dog and tail story. The iron involvment folloed
the failure of the normal regulation of it in the body. Iron was not
the cause of the disorder as such but the failure of the normal
regulation was one factor.

Another kick in the ass for the iron idea causing all disease because we
get it from eating meat.

ironjustice

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Jan 7, 2010, 9:08:38 PM1/7/10
to
On Jan 7, 6:03 am, ferr...@paris.com wrote:
Another kick in the ass for the iron idea causing all disease because
we
get it from eating meat. <<

Take your agenda .. and fkff like you've been TOLD ..

You have ONE reason to be here ..

THAT is to attempt to tell people they are NOT to target the iron ..

The article mentions how one SHOULD .. target the iron ..

You should actually try to tell people not to target the iron on
threads
where it doesn't obviously tell them to target the iron ..

It makes you look like you are either stupid or subversive ..

You already know what the punishment should be for that ..

fer...@paris.com

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Jan 8, 2010, 8:48:49 AM1/8/10
to
"We conclude that iron dysregulation may contribute significantly to
MS susceptibility"

"I hear alot of .. commotion .. about Dr. Zamboni and his effective


method of multiple sclerosis treatment. We .. don't .. hear alot of
discussion about removal of the iron. We JUST hear about how .. easy ..
Dr. Zamboni's treatment .. is. The iron ITSELF seems was never
addressed."


We don't need to consult anyone else, we can use the bit you provided
above. It is not the mere presense of iron, it is always there in every
cell, it is when the regulation system of iron becomes faulty that the
disorder seems to appear.

In other words, the old dog and tail story. The iron involvment folloed
the failure of the normal regulation of it in the body. Iron was not
the cause of the disorder as such but the failure of the normal
regulation was one factor.

Another kick in the ass for the iron idea causing all disease because we

get it from eating meat.

The response:

"
Take your agenda .. and fkff like you've been TOLD ..

You have ONE reason to be here ..

THAT is to attempt to tell people they are NOT to target the iron .."

Nonsense, it is to show how faulty and full of errors of fact and
confused your obsession with an idea shown to be dead as a dodo. It is
to suggest to those concerned with this disorder you are not to be taken
seriously in the least. It is to say they should consult an expert in
this disorder.

ironjustice

unread,
Jan 8, 2010, 10:40:22 AM1/8/10
to
On Jan 8, 5:48 am, ferr...@paris.com wrote:it is when the regulation

system of iron becomes faulty that the
disorder seems to appear. <<

Target the iron .. ?

Is that what it says .. ?

What are you doing here again .. ?

Being the fkg goof that you .. are .. ?

Goofs are NOT allowed ..

Soooo .. fkff .. like you HAVE been TOLD you fkg .. goof ..


------


Who loves ya.
Tom


------


Who loves ya.
Tom

> "We conclude that iron dysregulation may contribute significantly to

fer...@paris.com

unread,
Jan 8, 2010, 5:37:07 PM1/8/10
to
In other words, the old dog and tail story. The iron involvment folloed
the failure of the normal regulation of it in the body. Iron was not
the cause of the disorder as such but the failure of the normal
regulation was one factor.

The response:

"Target the iron .. ?"

Sure, but the reason for the iron is the failure of the normal
regulation of it.

As said, the old dog and tail thing.

ironjustice

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Jan 8, 2010, 5:59:39 PM1/8/10
to
On Jan 8, 2:37 pm, ferr...@paris.com wrote: snip <<

fer...@paris.com

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Jan 9, 2010, 10:29:37 AM1/9/10
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"Goofs are NOT allowed .."

Even when in the presence of micky mouse?

ironjustice

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Jan 9, 2010, 11:35:45 AM1/9/10
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