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Addison's Disease, any info would be appreciated
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 More options Jun 23 2007, 12:57 pm
Newsgroups: rec.pets.dogs.behavior, rec.pets.dogs.health, alt.med.veterinary, alt.support.grief.pet-loss, rec.pets.dogs.breeds
From: Human_And_Animal_Behavior_Forensic_Sciences_Research_Laborat...@HotMail.Com
Date: Sat, 23 Jun 2007 09:57:59 -0700
Local: Sat, Jun 23 2007 12:57 pm
Subject: Re: Addison's Disease, any info would be appreciated
HOWEDY reesecups,

"Reesecups" <reesec...@noplace.com> wrote in message

news:7rli7398e5evi0d7vq5e57gphvksj87ot4@4ax.com...

> Hi everyone,

WELCOME to The Sincerely Incredibly Freakin
Insanely Simply Amazing Grand Puppy, Child,
Pussy, Birdy, Goat, Ferett, Monkey And Horsey
Wizard's 100% CONSISTENTLY NEARLY INSTANTLY
SUCCESSFUL FREE WWW Wits' End Dog, Child, Kat,
Goat, Ferett, Monkey And Horse Training Method
Manual Forums And Human And Animal Behavior
Forensic Sciences Research Laboratory <{); ~ ) >

I'm Jerry Howe, The Sincerely Incredibly Freakin Insanely
Simply Amazing Grand Puppy, Child, Pussy, Birdy, Goat,
Ferett, Monkey And Horsey Wizard <{) ; ~ ) >

              Here's Your Own FREE COPY Of

      The Sincerely Incredibly Freakin Insanely Simply
                     A-M-A-Z-I-N-G
                       G-R-A-N-D
      Puppy, Child, Pussy, Birdy, Goat, Ferett, Monkey
                  And Horsey Wizard's
               100% CONSISTENTLY NEARLY
                 INSTANTLY SUCCESSFUL
                      ***FREE***
  WWW Wits' End Dog, Child, Kat, Goat, Ferett, Monkey
              And Horsey Training Method
                     Manual<{) ; ~ )>

                      <{#}: ~ } >8< { ~ :{@}>
                 <{#}: ~ } >           < { ~ :{@}>
           <{#}:~} >                         < {~ :{@}>
       <{}:~}>www.smart.net/~pstech/HoweManual.txt<{}:~}>
          <{#}: ~ } >                       < { ~ :{@}>
                <{#}:~} >               < { ~ :{@}>
                      <{#}: ~ } >8< { ~ :{@}>

> My dog Muffin, who is an 8-year old Shih Tzu has
> been lethargic lately and wouldn't eat her food
> in the morning.  Took her to the vet and they
> did an urinalysis and senior blood screening on her.

> Found she had a urinary tract infection as well
> as a problem with her electrolytes.  The vet said
> that the problem they are seeing with her electrolytes
> might be one or two things but the one that fit her
> symptoms the best was Addison's disease.

Addison's DIS-EASE is CAUSED BY STRESS from toxic
veterinary care e.g. EXXXCESSIVE vaccinations and
parasite treatments, unnecessary inapupriate surgical
sexual mutilation, commercial garbage diet and constant,
low level, intermittent STRESS from MISHANDLING, like
bribing, crating, punishing, ignoring and scolding <{}: ~ ( >

> The vet said the lethargy problem Muffin has had
> off and on since a young age plus the vomiting of
> food she has been doing, combined with the test
> results makes her suspect it.

Your vet GOT IT BACKWARDS. THOSE are SYMPTOMS
of STRESS culminating in a DIAGNOSIS of Addison's DIS-
EASE, a STRESS INDUCED AUTO-IMMUNE DIS-EASE
aka The Puppy  Wizard's Syndrome <{}: ~ ( >

The adrenals get STRESSED EVERY time the dog is told
"NO" or otherWIZE scolded punished intimidated ignored
or offered and withheld of bribes rewards attention or
affection as taught by HOWER EXXXPERT dog trainers
and behaviorists.

NOT TO WORRY HOWEver, you're in EXXXCELLENT
COMPANY of dog lovers like diddler and suja  <{}: ~ ( >

> Once the urinary tract infection is cleared up,

Urinary tract and ear infections and intermittent vomiting are
CAUSED BY STRESS from MISHANDLING as stated above.

> she is going to run another blood work on her
> for the electrolytes to see if they are a
> problem again.

Your veterinary malpracticioner will waltz you
by your willie till you got no doGdameneD more
money left to pay her and not enough dog left
but to do anything other than take the LAST of
your hard earned dough to "put her to sleep",
"the KINDEST GIFT you can give your dog" <{}: ~ ( >

> Anyway,

You mean 'anyHOWE', just HOWETA RESPECT.

> I'm sorry for making a short story long, but
> does anyone in here have a dog with Addison's
> disease

There's quite a few dog lovers here who's dogs are DYIN
from Addisons and it's C-HOWENTER part, Cushings
DIS-EASE, and a variety of cancers and psychogenic
aka IDIOPATHIC seizures  <{}: ~ ( >

> and if so, how do they treat it and what does it cost?

It'll cost you ALL you CAN AFFORD <{}: ~ ( >

> What other symptoms does a dog show
> that has Addison's Disease?

kevin's dog Fidget DIED from it.

> Any help would be appreciated...

You AIN'T gonna be gettin no doGdameneD
advice from these pathetic miserable stinkin
lyin animal murderin punk thug coward active
accute chronic life long incurable mental cases
other than SHARING your SAD TAILS and their
SYMPATHY  <{}: ~ ( >

> Thank you,

You're welcome.

> reesecups

Your dog has infections and Addison's on accHOWENTA
STRESS destroys the AUTO-IMMUNE system by inhibiting
absorbtion of enzymes minerals and acids and increases
cortisol and interluken-6 and taxes EVERY nerve fiber in
the body at the cellular level. You can successfully treat it
using a well balanced natural diet and carefully researched
micronutrients and natural glandular supplements.

Google shows about 267,000 for addison's and stress.

The Sincerely Incredibly Freakin Insanely Simply
Amazing Grand Puppy, Child, Pussy, Birdy, Goat,
Ferett, Monkey And Horsey Wizard DOES NOT
ENDORSE the treatment pracitces in the following
information.

Here's the standard "information" abHOWET Addison's.

"Addison's disease occurs more commonly in female dogs

Addison's disease (hypoadrenocorticism) is caused by a

lower than normal production of hormones, such as

cortisol, by the adrenal glands. The adrenals are small

glands that are located near the kidneys. Adrenal

hormones are necessary to control salt, sugar and water

balance in the body.

Addison's disease occurs less commonly than the opposite

condition, Cushing's disease (overproduction of cortisol)

in dogs, and is rare in cats.

Addison's disease occurs most commonly in young to

middle-aged female dogs. The average age is about
4 years old.

Signs of Addison's disease may appear suddenly, or be

intermittent     The signs of Addison's disease may be

severe and appear suddenly, or may occur intermittently

and vary in severity. Signs may include weakness,

depression, lack of appetite, vomiting, diarrhea, and

occasionally increased thirst (polydipsia) and increased

urine production (polyuria).

When a pet is stressed, their adrenal glands produce more

cortisol, which helps them deal with the stress. Because

dogs with Addison's disease cannot make enough cortisol,

they cannot deal with stress, so the signs may occur or

worsen when stressed. What a dog finds stressful depends

upon his/her temperament. For many dogs, any change in

their day-to-day routine, such as being boarded or having

house guests, is stressful and may precipitate or worsen

signs of Addison's disease.

On examination of dogs with Addison's disease one may
see depression, weakness, dehydration, weak pulses and
sometimes a slow, irregular heart rate.

Dogs with Addison's disease cannot cope with stress

Routine laboratory tests often show a low blood sodium

and high blood potassium. Loss of water, in vomit and

diarrhea, can lead to dehydration. Severe dehydration

increases waste products in the blood (creatinine and

blood urea nitrogen = BUN) that are normally eliminated

by the kidneys. Addison's disease can be confused with

primary kidney disease. Some dogs with Addison's disease

have low blood sugar. See What Do Those Lab Tests Mean?

for additional information about laboratory tests.

Sick dogs often show a pattern of changes in their white

blood cells (WBCs) called a stress leukogram. This

pattern of changes in the WBCs is caused by cortisol. The

absence of a stress leukogram in a sick dog may be a clue

to consider Addison's disease. The urine is often dilute.

Increased blood potassium can cause life-threatening

abnormalities in the heart rhythm. These abnormalities

can cause the heart rate to be slow and irregular and can

be seen on an electrocardiogram (ECG).

X-rays of dogs with Addison's disease do not show any

specific abnormalities. The heart may appear smaller
than normal and rarely the esophagus (tube from mouth
to stomach) can be enlarged.

The history, physical examination, and initial laboratory

tests provide suspicion for Addison's disease, but a more

specific test, an ACTH challenge, should be performed to

confirm the disease .

Long-term treatment can be given by mouth or as a shot

There are two stages of treatment for Addison's disease;

in-hospital treatment and long term treatment. Very sick

dogs with Addison's disease require intravenous fluids,

cortisol-like drugs and drugs to neutralize the effects

of potassium on the heart.

Long-term treatment involves the administration of

hormones in one of two forms; either a daily pill
or a shot that is given about every 25 days. Because
dogs with Addison's disease cannot produce more cortisol
in response to stress, stress should be minimized

whenever possible. It may be necessary to increase the

amount of hormones given during periods of stress (e.g.

boarding, surgery, travel, etc.).

With appropriate treatment for Addison's disease, dogs

can live a long and happy life.

Washington State University assumes no liability for

injury to you or your pet incurred by following these

descriptions or procedures.

             ==================

Autoimmune thyroiditis (hypothyroidism) is generally

found with the other autoimmune diseases or may occur
by itself. Loss of thyroid hormones is manifested early
by behavioral changes - aggression, hyperactivity,
anxiety/fear, compulsive behaviors, phobic behaviors;
allergies and reduced resistance to bacterial, viral,
fungal and protozoal infection - often manifest as skin
and respiratory disorders. Seizure disorders are also

often related to low thyroid levels. As the disease
progresses lethargy, obesity, alopecia (loss of hair/
poor haircoat especially on the sides) and infertility
are more common.

Hypoadrenocorticism (Addison's disease): The adrenal

gland produces hormones which regulate the level of
sodium and potassium (mineralocorticoids) and mediate
the body's response to physiologic and psychologic
stress (corticosteroids).

The former are needed to maintain proper cell function,
their loss is seen as muscle weakness and eventually
heart failure as the heart's muscle cells can no longer
produce the nervous impulses needed for the heart to
contract. Gastrointestinal function is also usually
impaired, and weight loss is frequently seen. Animals
are less able to cope with mild, everyday occurences
and hide, refuse to eat and show other symptoms of

stress.

SLE: Known as the great imitator can be hard to
diagnose as it can manifest as a disease of the
skin/mucous membranes/nails, kidney and/or joints
as has already been described. SLE can also affect
the brain producing signs of cognitive dysfunction.
It is also hard to diagnose definitively as not all
dogs with SLE have postive ANA titers.

Cause of Addison's Disease:  Failure to produce
adequate levels of cortisol, or adrenal insufficiency,
can occur for different reasons. The problem may be
due to a disorder of the adrenal glands themselves
(primary adrenal insufficiency) or to inadequate
secretion of ACTH by the pituitary gland (secondary
adrenal insufficiency).

Addison's disease is a rare endocrine or hormonal

disorder that affects about 1 in 100,000 people.
It occurs in all age groups and afflicts men and
women equally. The disease is characterized by
weight loss, muscle weakness, fatigue, low blood
pressure, and sometimes darkening of the skin in
both exposed and nonexposed parts of the body.

Addison's disease occurs when the adrenal glands do
not produce enough of the hormone cortisol and in
some cases, the hormone aldosterone. For this reason,
the disease is sometimes called chronic adrenal
insufficiency, or hypocortisolism.

                   --------

       Risks Associated With Synthetic Thyroid /
             Prescription Medications

                      And
          Thyroid Augmentation Therapy -
                CHICKEN NECKS!
    A Possible Solution for Refractory Depression
  By James D. Milton, Ph. D., Sc. D. June 17, 2003

              From The Annals Of
         Human And  Animal Behavior
     Forensic Sciences Research Laboratory
                    AND
          COLLEGE OF HARD KNOCKXXX
                <{} : ~ (  >

Researchers at Pennington Biomedical Research
Center published a study in the journal Thyroid
proving synthetic thyroid hormone depletes
calcium weakening the skeleton, increaing risk
of osteoporosis and bone loss.

Synthetic thyroid binds with iron, causing anemia
and fatigue, hair loss, brittle nails and general
susceptibility to DIS-EASE. The Freaking Simply
Amazing Puppy Wizard's friend Dr. VonHilseimer
recommends eating chicken necks as a natural
source of thyroid (see Pottinger Price Foundation
for more information).

Other researchers report many prescription drugs
like antibiotics may deprive the body of folic acid
which can increase homocysteine, an amino acid
linked to heart disease, anemia, fatigue, depression,
insomnia, nerve inflamation and increased risk of
cancers.

Depletion of magnesium can lead to formation
of kidney stones, clotting problems, muscle
spasams, generalized PAIN, constipation,
fatigue, high blood pressure.

Amoxycillin, ciprofloxacin, lansoprazole, cipro,
amoxil, augmentin, flonase, fosamax, zocor, liptor,
glucophage, tri-cyclen, prevacid, prilosec, prozac,
levothyroxine, azithromycin, simvastatin, omeprazole,
pantoprazole may drain the body of specific nutrients
e.g. statin drugs can deplete CoQ10, resulting in
fatigue, weight gain, high blood pressure, reduced
muscle performance and congestive heart failure.

Omega-3 fatty acids are important in the production
of hormones that act in nearly every body system
including the eyes, digestion, liver, stomach, large
intestine, urinary tract, kidney, skin and respiratory
systems. Without fatty acids skin would be dry, flaky,
wounds wouldn't heel pupperly, plaque would form on
arteries, and cause low blood pressure and arythmias.

                ============

Subject:   giving my puppy a chicken neck?
From:      Tracy Landauer
Date:      Sun, Dec 12 1999 12:00 am
Email:     Tracy Landauer <trac...@ix.netcom.com>

Funny, hypothyroid was one of the reasons I first

proceeded down this diet path as well.  With the
same end results: normal thyroid levels.

Tracy Landauer

          Thyroid Augmentation Therapy -
  A Possible Solution for Refractory Depression
    By James D. Milton, Ph. D., Sc. D. June 17, 2003

INTRODUCTION

Thyroid Augmentation Therapy (TAT) is not new. It
was pioneered by Drs. Whybrow and Bauer. I have
known about it since 1985 when it was successfully
used on me by my psychiatrist, Dr. Dean Ackley.

Since TAT's effectiveness has been proven beyond
question for many patients, it remains a Total
Mystery to me why it is not a standard psychiatric
tool for alleviating depression when patients do
not satisfactorily respond to antidepressants.

Since many papers have been published on the success
of TAT, the only explanations I can come up with are
either (1) an unwillingness to try a new approach to
controlling depression or (2) ignorance of TAT.

The only real disadvantage of TAT is that there is
no test that can be made beforehand to determine
whether or not a patient will respond favorably.

The same holds true for ALL antidepressants.
It is known that females outnumbe males by
approximately 8 to 1 who successfully alleviate
their depression by using TAT.

Whether that ratio is influenced by a greater
number of females undergoing TAT, I do not know.

Refractory or treatment-resistant depression occurs
with those who are clinically depressed as well as
those who have unipolar depression and bipolar disorder.

It unfortunately turns out that the existing
antidepressants are not the complete answer for
everyone.

It is my firm belief that Thyroid Augmentation
Therapy should be tried for every patient who
does not respond well to standard antidepressant
therapy. It may well turn out that all that is
needed is TAT for a person in order to control
his/her depression. Another may require TAT plus
an antidepressant - but without TAT that same
antidepressant would be totally ineffective.

I fall in this latter category.

WHAT IS THYROID AUGMENTATION THERAPY?

TAT consists of simply taking sufficient amounts
of artificial thyroid hormones (T3 and T4) to raise
the Free T3 and Free T4 levels to be in the 125-150%
ranges of their respective normal maximum amounts.

It is Totally Inadequate for a doctor to say that
your thyroid panel is "normal" and therefore you
have nothing to worry about. What TAT does is to
make your thyroid hormone levels abnormal - thereby
controlling many patient's depression!

HOW IS THYROID AUGMENTATION THERAPY ACCOMPLISHED?

Some doctors make the mistake of only adjusting
the Free T4 level by giving Synthroid, Levoxyl,
or another artificial source of T4. This will
somewhat increase the Free T3 level since T4 is
naturally converted into T3. However IMO it is
unlikely that a sufficiently high Free T3 level
 will be achieved by this means.

What needs to be done is to add artificial T3
(Cytomel) to the artificial T4 dose. The T4
dose should be titrated first before starting
upon adding the Cytomel.

All that really needs to be measured is the
Free T3 and Free T4 levels.

It has been found that once these reach 125-150%
of the laboratory's maximum values (each lab values
vary slightly), depression will begin to lift for
those whom TAT is effective.

Doctors will insist on wasting money on
measuring your TSH

(Thyroid Stimulating Hormone) level which will go
practically to zero. They will invariably panic not
understanding that is precisely what it should be
since you are taking thyroid supplements and there
is absolutely No Need for your thyroid to be producing
any hormones whatsoever! They will also want to waste
more money getting the Total T3 and Total T4 levels.

These are also meaningless  because these are BOUND

hormones and therefore not available to your brain!

Only the FREE levels have any meaning! Why pay
for anything else?

Your best bet is to get your psychiatrist or a
knowledgeable endocrinologist to adjust your
Free T3 and Free T4 levels. I would not even
bother with a family practitioner or an internist.
It is highly unlikely they will have even heard of
TAT. They will also worship at the Shrine of TSH.

FINAL THOUGHTS

For your information I take 25 micrograms of Cytomel,
112 micrograms of Levoxyl each once daily, and 37.5
mg of Effexor XR twice daily. My depression is history!

Potential adverse side effects if you get too much
T3 or T4 are headaches and heart irregularities. I
have never experienced either. If you do, I suggest
reducing your dosage.

Both pills are scored.

I had a bunch of references on this subject -
but they got lost when my operating system died.

I do hope that you will discuss Thyroid
Augmentation Therapy with your pdoc.

What have you got to lose - except your depression?

James

                 ----------------------

Cushing's syndrome is a disorder of the adrenal glands
leading to excess cortisol secretion. This means that
there is too much cortisol hormone in the blood. It can
be caused by an adrenal gland failure, or it can result
from a pituitary tumor or other tumor that secretes ACTH
which in turn stimulates the adrenal glands to
over-produce cortisol.

Cushing's syndrome information: Cushing's syndrome
is a hormonal disorder caused by prolonged exposure
of the body's tissues to high levels of the hormone
cortisol. Sometimes called "hypercortisolism," it is
relatively rare and most commonly affects adults aged
20 to 50. An estimated 10 to 15 of every million people
are affected each year. 1

Prevalance of Cushing's syndrome: it is relatively rare
and most commonly affects adults aged 20 to 50. Exposure
to too much cortisol can occur for different reasons such
as long-term use of glucocorticoid hormones to treat
inflammatory illnesses; pituitary adenomas (benign
tumors of the pituitary glands) which secrete increased
amounts of adrenocorticotropic hormone (ACTH); ectopic

ACTH syndrome (a condition in which ACTH is produced by
various types of potentially malignant tumors that occur
in different parts of the body); and adrenal tumors
(tumors of the adrenal glands). 2 Sometimes, an
abnormality of the adrenal glands, most often an adrenal
tumor, causes Cushing's syndrome.

Cause details for Cushing's syndrome: Cushing's syndrome
occurs when the body's tissues are exposed to excessive
levels of cortisol for long periods of time. Many people
suffer the symptoms of Cushing's syndrome because they
take glucocorticoid hormones such as prednisone for
asthma, rheumatoid arthritis, lupus or other inflammatory

diseases.

Others develop Cushing's syndrome because of over
production of cortisol by the body. Normally, the
production of cortisol follows a precise chain
of events. First, the hypothalamus, a part of the
brain which is about the size of a small sugar cube,
sends corticotropin releasing hormone (CRH) to the
pituitary gland. CRH causes the pituitary to secrete
ACTH (adrenocorticotropin), a hormone that stimulates
the adrenal glands.

When the adrenals, which are located just above the

kidneys, receive
the ACTH, they respond by releasing cortisol into the

bloodstream.

Cortisol performs vital tasks in the body. It helps
maintain blood pressure and cardiovascular function,
reduces the immune system's inflammatory response,
balances the effects of insulin in breaking down sugar
for energy, and regulates the metabolism of proteins,
carbohydrates, and fats. One of cortisol's most
important jobs is to help the body respond to stress.
For this reason, women in their last 3 months of
pregnancy and highly trained athletes normally have
high levels of the hormone.

People suffering from depression, alcoholism,
malnutrition and panic disorders also have
increased cortisol levels.

When the amount of cortisol in the blood is adequate,
the hypothalamus and pituitary release less CRH and
ACTH. This ensures that the amount of cortisol released
by the adrenal glands is precisely balanced to meet the
body's daily needs. However, if something goes wrong
with the adrenals or their regulating switches in the
pituitary gland or the hypothalamus, cortisol production
can go awry. 1

                     -----------

Autoimmune diseases information: Disease caused by
a malfunctioning immune system leading to self-
attacks or self-stimulation of other body cells.

Autoimmune diseases information: The word "auto" is
the Greek word for self. The immune system is a
complicated network of cells and cell components
(called molecules) that normally work to defend the
body and eliminate infections caused by bacteria,
viruses, and other invading microbes. If a person
has an autoimmune disease, the immune system mistakenly
attacks self, targeting the cells, tissues, and organs
of a person's own body. A collection of immune system
cells and molecules at a target site is broadly referred
to as inflammation.

Conditions list: The list of conditions in the
Autoimmune diseases group includes:

http://www.wrongdiagnosis.com/a/ai/intro.htm

    * Possibly Autoimmune Diseases
    * Type 1 diabetes
    * rheumatoid arthritis
    * Autoimmune thyroid diseases
    * Graves Disease
    * Hashimoto's Thyroiditis
    * Systemic Lupus Erythematosus
    * Multiple Sclerosis
    * Crohn's disease
    * Psoriasis
    * Psoriatic Arthritis
    * Sympathetic ophthalmitis
    * Autoimmune neuropathies
    * Autoimmune oophoritis
    * Autoimmune orchitis
    * Autoimmune Lymphoproliferative Syndrome
    * Antiphospholipid syndrome
    * Sjogren's Syndrome
    * Rheumatoid arthritis
    * Scleroderma
    * Lupus
    * Addison's Disease
    * Polyendocrine deficiency syndrome
    * Polyendocrine deficiency syndrome type 1
    * Polyendocrine deficiency syndrome type 2
    * Guillain-Barre Syndrome
    * Immune Thrombocytopenic Purpura
    * Pernicious anemia
    * Myasthenia Gravis
    * Primary biliary cirrhosis
    * Mixed connective tissue disease
    * Primary Glomerulonephritis
    * Vitiligo
    * Autoimmune uveitis
    * Autoimmune Hemolytic Anemia
    * Autoimmune Thrombocytopenia
    * Celiac Disease
    * Dermatitis herpetiformis
    * Autoimmune Hepatitis
    * Pemphigus
    * Pemphigus Vulgaris
    * Pemphigus Foliaceus
    * Bullous Pemphigoid
    * Autoimmune Myocarditis
    * Autoimmune Vasculitis
    * Autoimmune eye diseases
    * Alopecia Areata
    * Autoimmune Atherosclerosis
    * Behcet's Disease
    * Autoimmune Myelopathy
    * Autoimmune Hemophilia
    * Autoimmune Interstitial Cystitis
    * Autoimmune Diabetes Insipidus
    * Autoimmune Endometriosis
    * Relapsing Polychondritis
    * Ankylosing Spondylitis
    * Autoimmune Urticaria
    * Paraneoplastic Autoimmune Syndromes
    * Dermatomyositis
    * Miller Fisher Syndrome
    * IgA nephropathy
    * Goodpasture syndrome
    * Herpes gestationis

Hans Selye Hans Selye was born in Vienna in 1907.
As early as his second year of medical school (1926),
he began developing his now-famous theory of the
influence of stress on people's ability to cope
with and adapt to the pressures of injury and disease.

He discovered that patients with a variety of ailments
manifested many similar symptoms, which he ultimately
attributed to their bodies' efforts to respond to the
stresses of being ill.

He called this collection of symptoms--this separate
stress disease--stress syndrome, or the general
adaptation syndrome (GAS).

He spent a lifetime in continuing research on GAS and
wrote some 30 books and more than 1,500 articles on
stress and related problems, including Stress without
Distress (1974) and The Stress of Life (1956).

So impressive have his findings and theories been
that some authorities refer to him as "the Einstein
of medicine."

A physician and endocrinologist with many honorary
degrees for his pioneering contributions to science,
Selye also served as a professor and director of the
Institute of Experimental Medicine and Surgery at the
University of Montreal.

More than anyone else, Selye has demonstrated the
role of emotional responses in causing or combating
much of the wear and tear experienced by human beings
throughout their lives. He died in 1982 in Montreal,
where he had spent 50 years studying the causes and
consequences of stress.

        Stress, Cortisol / Interluken-6, =
           The Puppy Wizard's SYNDROME

HOWEDY People,

Here's some interesting stuff all abHOWET HOWE
STRESS causes The Puppy Wizard's SYNDROME:

Veterinarian treats thousands of pets with multiple
illnesses from chronic infections to autoimmune

conditions and finds a common anomaly - adrenal/
thyroid hormonal-imbalances & deficiencies

The adrenals are a pair of ductless glands that sit
atop the kidneys in the lower part of the back. New
insights on metabolism and hormonal balance indicate
that the adrenals and thyroid have a direct role in
energy production, well-being, allergies, immune
function and many other areas of human health.

An article by Alfred J Plechner DVM and M. Zucker
"Unrecognized endocrine-Immune Defects in Multiple
Diseases: An Effective Veterinary model may offer
Therapeutic promise for human conditions. A mutual
friend, Martin Zucker, sparked my interest in Plechners
theories and treatment approach. Zucker stated that
Alfred Plechner has developed a simple protocol for
treating cats, dogs and other pets that have chronic
infections and multiple health problems that do
not resolve on their own.

The protocol involves diagnostic testing for certain
thyroid and adrenal hormones followed by low-dose
adrenal and thyroid replacement hormones that are
used together rather than separately. The result of the
treatment is that Adrenal estrogen production declines
and stops binding to thyroid hormones. The end result
is that thyroxin is freed-up to increase ATP production
in the cells. This normalizes body temperature and cell-
mediated immune functions improve.

According to Zucker, Plechner treated dozens of cats with
FIV infection. Zucker stated that the treatment restored
normal immune function. FIV stands for Feline
Immunodeficiency Virus. The equivalent in humans is HIV.

I asked Zucker if this treatment approach has ever
been used in humans to treat HIV? He said that to
his knowledge it has not. One wonders what Plechner's
protocol would do for HIV and other immune deficiency
diseases including CFIDS, candidiasis, cancer, hepatitis,
Lyme disease, lupus, MS, allergies and autoimmune
diseases. Will it bring us closer to a cure for AIDS
or a control that has little or no side effects?

How and why do deficits and imbalances in endocrine
hormones affect the immune system? We know that
hypothyroidism (low thyroid function) leaves a person
vulnerable to one chronic infection after another.

In Wisconsin, Dennis, a local PWA, HIV since 1983
has had above normal body temperature all his life
and after all these years, still no HIV progression.
Never on drugs his viral load is still under 1000.

In a separate phone call to Alfred Plechner, I asked
him what exactly is his treatment protocol? Here was
his reply.

Alfred: The treatment consists of giving low dose
thyroid hormones along with low-dose cortisone.

Mark: You mean low-dose thyroid hormones like Armour
Thyroid that provide the thyroid hormone "thyroxin"
and Cortone that provide one of the adrenal hormones

cortisone or its most active form - hydrocortisone?

Alfred: Yes, the equivalent of these drugs for use in
humans is available by prescription for household pets
and other animals. The amount given varies according to
the weight of the animal and the results of diagnostic
tests. If I were treating an adult human, I would start
off with 1/2 grain of thyroid (about 60 mg) and 5 mg of
cortisone twice a day. You need to monitor blood pressure
when giving thyroid as too much could cause it to rise
as well as increase the pulse rate. The process of
increasing thyroid use has to be gradual. Usually the
amount of cortisone used is maintained at a low level.

Mark: I can understand the role of the thyroid hormone
as it controls cellular metabolism throughout the body
the production of ATP and will help in normalizing body
temperature that is critical for restoring cell-mediated
immune responses, but cortisone, is it not

immunosuppressive?

Alfred: Absolutely, if you take too much of it. The same
is true for zinc. Research has shown that too little zinc
or too much is immunosuppressive and this has been shown
for other nutrients as well. You absolutely need zinc for
your thymus gland to function properly and mature T cells
but you don't want too much or too little. Experience has
shown that 15 to 30 mg daily is a safe and effective
dosage range.

Now for cortisone, it is a natural anti-inflammatory
hormone and the normal healthy human body produces
about 40 mg daily. It is well established that too
much cortisone is immunosuppressive, in fact, for
this reason alone, cortisone has a bad reputation.
What is not known is that too little free cortisol
is immunosuppressive. There are many people treated
with thyroid hormones that get their body temperature
back to normal and many who do not. One reason is that
part of the Adrenal glands are exhausted and are not
producing enough cortisol and another part of the
Adrenal glands are producing too much estrogen that
binds to thyroxin. The production of cortisol is
controlled through a feedback loop. Note: When
cortisone is administered, it is converted to the
active form called cortisol that is also known as
hydrocortisone.

Mark: What is a feedback loop?

Alfred: Cortisol levels are controlled by a classical
feedback loop that involves the hypothalamus-pituitary
and adrenal glands. Cortisol, the primary glucocorticoid,
is produced in the middle Adrenal cortex layer. We have
found a problem in cortisol production that comes from
two of three layers of the adrenal cortex. The defect
can be genetic or due to other causes (nutritional
deficiencies or toxins).

Cortisol stimulates several processes that serve to
increase and maintain normal glucose levels in the
blood, exert a potent anti-inflammatory effect and
act as a regulating factor for normal immune function.

Mark: Tell me more about this "loop" and how does
normalizing cortisol and estrogen levels affect the
functioning of the Thyroid gland and help restore
normal body temperature and cell-mediated immune

function?

Alfred: "The loop is called the hypothalamus -
pituitary - adrenal axis. Cortisol is secreted in
response to a single stimulator: AdrenoCorticoTropic

Hormone (ACTH) that is produced by the Pituitary
gland. ACTH is itself secreted under control of the
Hypothalamus and a hormone it secretes called
Corticotropic-Releasing Factor (CRF). Cortisol
secretion is suppressed or stimulated by classical
feedback loops. When blood concentrations rise
above a certain threshold, cortisol inhibits CRF
secretion. This, in turn, inhibits ACTH and less
ACTH reduces adrenal secretion of cortisol.

"However, when the adrenal gland is unable to produce
enough cortisol, or for some reason the cortisol is
bound, or otherwise inactive, and thus not recognized
by the system, the pituitary continues to produce ACTH
in order to extract more cortisol from the adrenals.

"The inner cortical layer, where adrenal estrogen is
produced, also responds to ACTH. The result of constant

ACTH stimulation in a situation where cortisol is bound
or deficient produces a release of adrenal estrogen into
the system.

As cortisol levels fail to reach the threshold to stop
the Hypothalamus from secreting CRF, the CRF stimulates
the Pituitary to continue to secrete ACTH. The ACTH tries
to get the Adrenal gland to produce cortisol but the same
ACTH also stimulates the adrenals to secrete estrogen.

As a result of an inability of the adrenals to keep up
with demand for cortisol, adrenal estrogen levels build
up and cause the following:

1. A histamine-like effect on capillaries, leading to
inflammation from blood components spilling into adjacent
tissues

2. Binding thyroid hormone

3. Further deregulation of lymphocytes and antibodies. "

Mark: Elevated histamine levels have been linked to
elevated interluken 6 levels in many studies. If the
histamine like effects are due to actual elevated
histamine levels then should not we also expect IL-6
levels to increase also; and if that were the case,
would we not also expect a shift in cytokine profiles
from TH1 to the less effective TH2?

Alfred: That is a good question. I have not investigated
whether or not IL-6 levels are elevated in these
conditions but I have found out that IgA levels are low
and these low levels in the digestive tract lead to food
allergies and sensitivities as well as malabsorption.

Mark: IgA is a TH1 cytokine needed for mucosal immunity.
Bifidobacteria Longum has been found to increase the
levels of IgA as does vitamin A. What are some of the
benefits of supplementing with low-dose thyroid and
cortisone you have observed in your clinical practice?

Alfred: After a trial and error period, I have developed
a testing and treatment strategy that has proved to safe
and highly effective. The central modality is replacement
with physiological doses of cortisone preparations to
address the root issue of cortisol deficiency. The
low-dose cortisone preparations normalize ACTH levels,
stop the overproduction of adrenal estrogen and the
accompanying estrogen blockade of the thyroid hormones
and reregulates the immune system.

The use of low dose cortisone long term has also been
reported by Jefferies for treating allergies, autoimmune
disorders and chronic fatigue syndrome (1).

The second important modality is the simultaneous use
of thyroid hormone. The thyroid hormone is needed because
the excess adrenal estrogen has bound some of the thyroid
hormone. The low dose thyroid hormone helps increase the
metabolic rate and the liver to detoxify as well as
process the cortisol. By giving cortisol and thyroid
replacement simultaneously, the body is able to
effectively utilize and process the former (cortisol)
without developing side effects.

Once the testing and low-dose hormone therapy is

underway, it is very important to follow a hypo-
allergenic diet and remove foods to which the
animal or person is sensitive.

After a few weeks, the sensitive foods may be

reintroduced one at a time.

Mark: Have you written and published other
articles on this subject?

Alfred: In the late 1970's, I wrote 4 articles
(2, 3, 4 and 5) on my experiences and theories
but found no germane research in veterinary
journals to provide guidance.

Mark: As a general guide for someone who has low body
temperature, low cortisol and high estrogen, what would

be a safe dose with which to start?

Alfred: For cortisol, 5 mg twice a day. Take at 8am
and 2pm. Do not take cortisone supplements in the
evening or before bedtime, as it will interfere with
the REM state of sleep.

We want cortisol levels higher when we are awake and
low when we are asleep. In normal subjects, cortisol
levels are highest at 8am in the morning. Also,
melatonin levels that help promote restful sleep
should be lowest during the day and increase after
dark and before bedtime. A melatonin spillover in the
AM can depress the basal metabolic rate all day.

This can be turned off by exposing the eyes to bright
natural lights for a few minutes or taking a walk outside
without wearing sunglasses.

For thyroid, 1/4 grain (about 15 mg) daily to start and
after a few weeks if blood pressure and pulse are not
elevated to gradually increase the thyroid amount. The
cortisol levels are left the same. The hormonal and

immune benefits will accrue and be maintained as long
as the person stays on the protocol.

A physician's prescription is required for both the
cortisol and thyroid hormones. The key here is low-dose
for successful long-term use as adverse effects may
develop from higher doses. Note: Thyroxine is a strong
inducer of IgA, a TH1 cytokine needed for intestinal
and mucosal health.

Ref: 1. Jefferies, w. McK. Mild adrencortical deficiency,
chronic allergies, autoimmune disorders and the chronic
fatigue syndrome: a continuation of the cortisone story.
Medical Hypothesis, 1994; 42;183-189

2. Plechner A. J., Shannon M., Canine Immune Complex
diseases. Modern Veterinary Practice, November 1976; 917

3. Plechner A. J., Shannon M., Epstein A, Goldstein E.,
Howard E. B., Endocrine-immune surveillance. Pulse.
June-July, 1978

4. Plechner A. J., Theory of endocrine-immune

surveillance.
California Veterinarian, Jan 1979; 12.

5. Plechner A. J. Preliminary observations on
endocrine-associated immunodeficiencies in dogs?
A clinician explores the relationship of
immunodeficiencies to endocrinopathy. Modern
Veterinary Practice, 1979; 811

Important Highlights from Alfred Plechner's article

35,000 pets treated with this protocol

Alfred Plechner states he has treated over 35000
pets in the past 20 years with this protocol.
Plechner reports that low cortisol and thyroid hormone
lowers T cell panels in the tests. Estrogen can exert
a dramatic blocking effect on cortisol and thyroid
hormones, and just a slight variation out of normal
is enough to cause hormonal and immune complications.

In this case, the relationship is usually low
cortisol, high estrogen and deregulated immune cells.

In female animals that are not neutered, testing is done
when the animals are not in estrus and are not producing
high levels of ovarian estrogen.

                       ---------------------------------------------

                                  A DOG Is A DOG;
                                As A KAT Is A KAT;
                            As A BIRDY Is A BIRDY;
                          As A HORSE Is A HORSE;
                            As A GOAT Is A GOAT;
                             As A Ferett Is A Ferett;
                          As A Monkey Is A Monkey;
                           As A CHILD IS A CHILD;
                  As A SP-HOWES Is a SP-HOWES;
              As A Mass Murderer Is A Mass Murderer.

                       ALL Critters Only Respond In
             PREDICTABLE INNATE NORMAL NATURAL
                   INSTINCTIVE REFLEXIVE Ways;
    To Situations And Circumstances Of Their Environment
                      Which We Create For Them.

                   You GET The Critter You TRAINED

              In The Problem Animal Behavior BUSINESS
                         FAILURE MEANS DEATH.
                        SAME SAME SAME SAME,
            For The Problem Child Behavior BUSINESS.

Sam Corson, Pavlov's Last Student Demonstrated At
UofOH Oxford, That Rehabilitation Of Hyperactive
Dogs Can Easily And Readily Be Done Using TLC.
Tender Loving Care Is At The Root Of The Scientific
Management Of Doggys.  <{) ; ~ ) >

"Despite Skinner's clear denunciation of "negative
reinforcement" (1958) NEARLY EVER LEARNING
THEORY model involves the USE OF PUNISHMENT.
Of curse, Skinner has never to my knowledge, demonstrated
HOWE we escape the phenomenon that an expected
reward not received is experienced as a punishment
and can produce extensive and persistent aggression
(Azrin et al, 1966)."

"The IMBECILITY of some of the claims for operant
technique simply take the breath away. Lovas et al
(1966) report a standard contingent reward/punishment
procedure developing imitative speech in two severly
disturbed non verbal schizophrenic boys. After twenty-
six days the boys are reported to have been learning
new words with alacrity. HOWEver, when REWARDS
were moved to a delayed contingency the behavior and
learning immediately deteriorated."

"...all the highest nervous activity, as it manifests
itself in the conditional reflex, consists of a continual
change of these three fundamental processes --
excitation, inhibition and disinhibition,"  Ivan P. Pavlov

"Postitive emotions arising in connection
with the perfection of a skill, irrespective
of its pragmatic significance at a given
moment, serve as the reinforcement. IOW,
emotions, not outside rewards, are what
reinforces any behavior," Ivan Pavlov.

"All animals learn best through play." -- Konrad Lorenz

"It is NO WONDER that the marked changes in
deviant behavior of children can be achieved
through brief, simple educative routines with
their mothers which modify the mother's social
behaviors shaping the child (Whaler, 1966). Some
clinics have reported ELIMINATION ofthe need for
child THERAPY through changing the clinical emphasis
from clinical to parental HANDLING of the child
(Szrynski 1965).

A large number of cases improved sufficiently after
preliminary contact with parents that NO treatment
of children was required, and almost ALL cases
SHOWE a remarkably shortened period for therapy.
Quite severe cases of anorexia nervosa have been
treated in own to five months by simply REPLACING
the parents temporarily with EFFUSIVELY LOVING
SUBSTITUTES (Groen, 1966)."

  Abuse / fear / aggression / hyperactivity / shyness / suicide
  attempts AIN'T a chemical imbalance or genetic problem,
                    it's a SPIRITUAL problem,
                             passed on
          from WON generatiHOWEN of  abuser
                            to the next,
     like the 100th  monkey washin fruit in the stream;
 After a while it's not just NORMAL, it's OBLIGATORY.

          To do otherWIZE would be DISRESPECTFUL
                       of your parental teachins.

              The Puppy Wizard's SYNDROME
                     Is the Perfect Synergy Of
           Love, Pride, Desire, Shame, Greed, Ego, Fear,
                        Hate, Reflex, Self Will,
         Arrogance, Ignorance, Predjudice, Cowardice,
         Disbelief, Jealousy, Embarrassment, Embellishment,
         Guilt, Anger, Hopelessness, Helplesness, Aversion,
         Attraction, Inhibition, Revulsion, Repulsion, Change,
         Permanence, Enlightenment, Insult, Attrition,
                                         And
            Parental / ReligiHOWES / Societal Conditioning.

         YOU ARE THE CRITTER YOU WAS TRAINED.

     It Is The Perfect Fusion Of The Word..., In The Physical.
            The Sincerely Incredibly Freakin Insanely Simply
                                 A-M-A-Z-I-N-G
                                    G-R-A-N-D
           Puppy, Child, Pussy, Birdy, Goat, Ferett, Monkey
                         And Horsey Wizard  <{) ; ~ ) >

 "Only the unenlightened speak of wisdom and right action
                          as separate, not the wise.

            If any man knows one, he enjoys the fruit of both.

               The level which is reached by wisdom
                                  is attained
                      through right action as well.

             He who perceives that the two are one
                             knows the truth."

          "Even the wise man acts in character with his nature,
          indeed all creatures act according to their natures.

                  What is the use of compulsion then?

                 The love and hate which are aroused
                  by the objects of sense arise from Nature,
                  do not yield to them.

                        They only obstruct the path," -
                                 - Bhagavad Gita,
                adapted by Krishna with permission
                from His OWN FREE copy of The Simply
                Amazing Puppy Wizard's FREE Wits' End
                Dog Training Method manual <{) ; ~ )  >

                            --------------------------

Here's professor dermer AFTER gettin JERRYIZED:

    "We Are Lucky To Have You, And More People
    Should Come To Their Senses And Support Your
    Valuable Work.

    God Bless The Puppy Wizard," Professor Marshall
    Dermer, Dept Of ANAL-ytic Behavior, UofWI.

 From: "Marshall Dermer" <der...@csd.uwm.edu>
 To: "The Puppy Wizard"
 <ThePuppyWiz...@earthlink.net>
 Sent: Friday, July 23, 2004 2:53 PM

 Subject: God Bless The Puppy Wizard
 Dear Mr. Puppy Wizard,

 I have, of late, come to recognize your genius
 and now must applaud your attempts to save
 animals from painful training procedures.

 You are indeed a hero, a man of exceptional talent­,
 who tirelessly devotes his days to crafting posts ­to
 alert the world to animal abuse.

 We are lucky to have you, and more people should
 come to their senses and support your valuable
 work.

 Have you thought of establishing a nonprofit
 charity to fund your important work?

 Have you thought about holding a press conference
 so others can learn of your highly worthwhile
 and significant work?

 In closing, my only suggestion is that you
 try to keep your messages short for most
 readers may refuse to read a long message
 even if it is from the wise, heroic Puppy Wizard.

 I wish you well in your endeavors.

 --Marshall Dermer

                   ----------------

Jerry Howe,
Director of Research,
Human And Animal Behavior
Forensic Sciences Research Laboratory,
BIOSOUND Scientific,
Director of Training,
Wits' End Dog Training
1611 24th St
Orlando, FL 32805
Phone: 1-407-425-5092
Email:
The_Insanely_Freakin_Simply_Amazing_Grand_Puppy_Wizard_ @HotMail.Com

                               In Love And Light,
                   I Remain Respectfully, Humbly Yours,
                                    Jerry Howe,
           The Sincerely Incredibly Freakin Insanely Simply
                                 A-M-A-Z-I-N-G
                                   G-R-A-N-D
          Puppy, Child, Pussy, Birdy, Ferett, Goat, Monkey
                         And Horsey Wizard  <{) ; ~ ) >

                   HOWE MAY I SERVE YOU <{}; ~ ) >


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