Aspirin.

[Ian Field]

Is there any reason a diabetic shouldn't use aspirin?

Thanks.

[Maya Zuiderweg]

Ian Field had uiteengezet :

> Is there any reason a diabetic shouldn't use aspirin?
>
> Thanks.

I think a hypo lures. Had an internist (endo?) who was horrified that I
took aspirin (danger: hypo). Must say though that I use insulin. So
maybe when using insulin its not a good idea to take aspirin.
M.

[outsider]

On 6/10/2013 4:30 PM, Ian Field wrote:
> Is there any reason a diabetic shouldn't use aspirin?
>
> Thanks.

Just be aware of all the warnings standard to Aspirin. It
is a blood thinner. I had bleeding ulcers twice caused by
Aspirin. The first one did me a favor. Because of that
bleeding ulcer I was able to give up smoking.

[Henry Mydlarz]

"outsider" <outs...@sometime.individual.net> wrote in message
news:b1n0sf...@mid.individual.net...

Because it is a blood thinner, beware of using it in conjunction with other
blood thinners such as some herbs. Gingko Biloba is one, I think Garlic and
St John's Wort are others. Discuss this with your doctor.

Henry

[W. Baker]

Henry Mydlarz <myd...@optusnet.com.au> wrote:
: "outsider" <outs...@sometime.individual.net> wrote in message

My endo doesn't want me using any NSAIDS like asprin because of potential
kidney issues and also no Tylenol becuase of potential liver damage. It
makes it great for the pain in my bad back, for which there is not much I
can take.

Wendy

[Julie Bove]

"Ian Field" <gangprob...@ntlworld.com> wrote in message
news:mArtt.85781$Dg1....@fx28.am4...

> Is there any reason a diabetic shouldn't use aspirin?
>
> Thanks.

Sure. If they have GERD, an ulcer or on a blood thinner.

[GysdeJongh]

Ian Field wrote:
> Is there any reason a diabetic shouldn't use aspirin?
>
> Thanks.

If you have diabetes *And* a high blood glucose your chance of
cardiovascular events is increased. Aspirin won't help because the glucose
in your blood and the Aspirin compete for the same reaction. The best thing
left is to lower your HbA1c to a reasonable level (< 8% if older) by
exercise and diet. After which you nolonger need Aspirin.


<http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777137/>

Cardiovasc Diabetol. 2009 Oct 30;8:57. doi: 10.1186/1475-2840-8-57.
Lack of benefits for prevention of cardiovascular disease with aspirin
therapy in type 2 diabetic patients--a longitudinal observational study.

BACKGROUND: The risk-benefit ratio of aspirin therapy in prevention of
cardiovascular disease (CVD) remains contentious, especially in type 2
diabetes. This study examined the benefit and harm of low-dose aspirin
(daily dose < 300 mg) in patients with type 2 diabetes. METHODS: This is a
longitudinal observational study with primary and secondary prevention
cohorts based on history of CVD at enrollment. We compared the occurrence of
primary composite (non-fatal myocardial infarction or stroke and vascular
death) and secondary endpoints (upper GI bleeding and haemorrhagic stroke)
between aspirin users and non-users between January 1995 and July 2005.
RESULTS: Of the 6,454 patients (mean follow-up: median [IQR]: 4.7 [4.4]
years), usage of aspirin was 18% (n = 1,034) in the primary prevention
cohort (n = 5731) and 81% (n = 585) in the secondary prevention cohort (n =
723). After adjustment for covariates, in the primary prevention cohort,
aspirin use was associated with a hazard-ratio of 2.07 (95% CI: 1.66, 2.59,
p < 0.001) for primary endpoint. There was no difference in CVD event rate
in the secondary prevention cohort. Overall, aspirin use was associated with
a hazard-ratio of 2.2 (1.53, 3.15, p < 0.001) of GI bleeding and 1.71 (1.00,
2.95, p = 0.051) of haemorrhagic stroke. The absolute risk of
aspirin-related GI bleeding was 10.7 events per 1,000 person-years of
treatment. CONCLUSION: In Chinese type 2 diabetic patients, low dose aspirin
was associated with a paradoxical increase in CVD risk in primary prevention
and did not confer benefits in secondary prevention. In addition, the risk
of GI bleeding in aspirin users was rather high.
PMID: 19878541


<http://jama.jamanetwork.com/article.aspx?articleid=182877>

JAMA. 2008 Nov 12;300(18):2134-41. doi: 10.1001/jama.2008.623. Epub 2008 Nov
9.
Low-dose aspirin for primary prevention of atherosclerotic events in
patients with type 2 diabetes: a randomized controlled trial.

CONTEXT: Previous trials have investigated the effects of low-dose aspirin
on primary prevention of cardiovascular events, but not in patients with
type 2 diabetes. OBJECTIVE: To examine the efficacy of low-dose aspirin for
the primary prevention of atherosclerotic events in patients with type 2
diabetes. DESIGN, SETTING, AND PARTICIPANTS: Multicenter, prospective,
randomized, open-label, blinded, end-point trial conducted from December
2002 through April 2008 at 163 institutions throughout Japan, which enrolled
2539 patients with type 2 diabetes without a history of atherosclerotic
disease and had a median follow-up of 4.37 years. INTERVENTIONS: Patients
were assigned to the low-dose aspirin group (81 or 100 mg per day) or the
nonaspirin group. MAIN OUTCOME MEASURES: Primary end points were
atherosclerotic events, including fatal or nonfatal ischemic heart disease,
fatal or nonfatal stroke, and peripheral arterial disease. Secondary end
points included each primary end point and combinations of primary end
points as well as death from any cause. RESULTS: A total of 154
atherosclerotic events occurred: 68 in the aspirin group (13.6 per 1000
person-years) and 86 in the nonaspirin group (17.0 per 1000 person-years)
(hazard ratio [HR], 0.80; 95% confidence interval [CI], 0.58-1.10; log-rank
test, P = .16). The combined end point of fatal coronary events and fatal
cerebrovascular events occurred in 1 patient (stroke) in the aspirin group
and 10 patients (5 fatal myocardial infarctions and 5 fatal strokes) in the
nonaspirin group (HR, 0.10; 95% CI, 0.01-0.79; P = .0037). A total of 34
patients in the aspirin group and 38 patients in the nonaspirin group died
from any cause (HR, 0.90; 95% CI, 0.57-1.14; log-rank test, P = .67). The
composite of hemorrhagic stroke and significant gastrointestinal bleeding
was not significantly different between the aspirin and nonaspirin groups.
CONCLUSION: In this study of patients with type 2 diabetes, low-dose aspirin
as primary prevention did not reduce the risk of cardiovascular events.
TRIAL REGISTRATION: clinicaltrials.gov Identifier: NCT00110448.
PMID: 18997198


J Mol Med (Berl). 2005 Feb;83(2):148-58. Epub 2004 Nov 10.
Increased protein glycation in diabetes mellitus is associated with
decreased aspirin-mediated protein acetylation and reduced sensitivity of
blood platelets to aspirin.

Reduced effectiveness of the most common antiplatelet drug, acetylsalicylic
acid (ASA, aspirin), in diabetes mellitus has been associated with a lowered
platelet sensitivity to ASA and related to glycemic control in diabetic
patients. Our objectives were (a) to monitor the chemical background of how
chronic hyperglycemia affects platelet response to ASA in diabetes and (b)
to study a chemical competition between the amount of bound acetyl residues
and the extent of protein glycation in blood platelets. Using whole-blood
impedance aggregometry and platelet function analyzer (PFA-100) we observed
a reduced platelet response to ASA in diabetic patients (14% vs. 79% for
PFA-100 collagen-epinephrine occlusion time) and an association between the
index of glycemic control and platelet refractoriness to ASA (r(S)
= -0.378). Impaired platelet response to ASA was related to enhanced
platelet protein glycation (3.6+/-0.4 in diabetes vs. 2.3+/-0.4 micromol
fructosamine/microg protein in control) and reduced incorporation of acetyl
residue into proteins of platelets from diabetic patients (47.4+/-2.0 in
control vs. 33.1+/-0.7 micromol acetyl/microg protein in diabetic subjects).
Incubation of blood platelets with increasing concentrations of glucose and
ASA under in vitro conditions led to excessive modification in protein amino
groups: glucose and ASA competed with each other in the course of
nonenzymatic modifications, glycosylation, or acetylation, and their
contributions to the occupancy of protein amino groups (R2 = 0.22 for
glucose, R2 = 0.43 for ASA) were dependent upon the concentrations of
glucose and ASA. Overall the effects of high glucose and high ASA on the
overall occupancy of protein free amino groups are not additive. While at
higher concentrations ASA overcomes the effects of hyperglycemia and retards
glycation, high glucose makes acetylation less efficient, and therefore the
resultant chemical modification becomes greatly reduced. In conclusion,
diminished susceptibility of various platelet proteins and receptors on
blood platelet membranes to acetylation and high ambient glucose might
underlie the apparently differentiated sensitivity of blood platelets to ASA
and determine platelet "insensitivity to aspirin" in diabetic patients.
PMID: 15723265

[Ian Field]

"Maya Zuiderweg" <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote in
message news:rp-dnTBxlrhZ0SvM...@giganews.com...

Still on Metformin - not graduated to insulin so far.

One particular problem I was having was at blood tests - they had a real
struggle drawing a blood sample, since I started aspirin its been no big
deal.

Another small problem was trivial injuries didn't have enough blood flow to
purge the depth of the wound, this made infection management more
challenging than it need be.

[outsider]

As I mentioned earlier, regular aspirin use led to bleeding ulcers. My
cardiologist had me cut back to the "baby" sized aspirin. As a blood
thinner, they have me taking two of those 81mg tablets per day.

My first bleeding ulcer happened at 49 years of age, long before
diabetes reared its ugly head.

[W. Baker]

GysdeJongh <JonghSevenHundredElevenAtPlanet.nl> wrote:

: Ian Field wrote:
: > Is there any reason a diabetic shouldn't use aspirin?
: >
: > Thanks.

: If you have diabetes *And* a high blood glucose your chance of
: cardiovascular events is increased. Aspirin won't help because the glucose
: in your blood and the Aspirin compete for the same reaction. The best thing
: left is to lower your HbA1c to a reasonable level (< 8% if older) by
: exercise and diet. After which you nolonger need Aspirin.

My Endo, who doesn't want me on NSAIDS for pain, as I mentioned before,
has me on 81 mg baby aspirin once a day . My A1c is currently 6.2, as he
cut my Metformin(which I have been using for some 16 of my 30 years
diabetes) in order to raise my A1c ab it because of my age(77). I op eto
never have to go onto insulin, but would were it necessary.

Wendy

[GysdeJongh]

Hi Wendy,
according to all the recent literature I know that is a wise compromise of
your endo : not too much med's and *Maybe* a bit Aspirin. The last time I
was in the 4% club. No med's no sup's. Reasonable exercise and diet (for my
age) I know I won't live forever. If I knew how to, I would not do it. I'll
be very glad when I'm done here.
Gys

[Maya Zuiderweg]

Ian Field schreef op 11-6-2013 :

I am not familiar with Metformin, I think you get no hypo (too low
bloodsugar) when on Metformin..?
Internist warned me later that Aspirin and insulin (by injection) _do_
interfere which each other.
So, other effects (as you mentioned: bleeding) can be a hazard.
M.

[Ian Field]

"Maya Zuiderweg" <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote in

message news:8cGdnZgtFMpcACrM...@giganews.com...

> Ian Field schreef op 11-6-2013 :
>>
>> "Maya Zuiderweg" <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote
>> in message news:rp-dnTBxlrhZ0SvM...@giganews.com...
>>> Ian Field had uiteengezet :
>>>> Is there any reason a diabetic shouldn't use aspirin?
>>>>
>>>> Thanks.
>>>
>>> I think a hypo lures. Had an internist (endo?) who was horrified that I
>>> took aspirin (danger: hypo). Must say though that I use insulin. So
>>> maybe when using insulin its not a good idea to take aspirin.
>>
>> Still on Metformin - not graduated to insulin so far.
>>
>> One particular problem I was having was at blood tests - they had a real
>> struggle drawing a blood sample, since I started aspirin its been no big
>> deal.
>>
>> Another small problem was trivial injuries didn't have enough blood flow
>> to purge the depth of the wound, this made infection management more
>> challenging than it need be.
>
> I am not familiar with Metformin, I think you get no hypo (too low
> bloodsugar) when on Metformin..?

One time I was too ill to eat for a while (not diabetes related) I had a
problem with the Metformin and had to stop taking it until I was well enough
to get a few meals under my belt.

Someone on the same ward described the onset of going hypo, it sounded
fairly similar to what I experienced.

The Pharmacist has also warned me not to take any before the first meal of
the day.

[Maya Zuiderweg]

Het is zò dat Ian Field formuleerde :

That's weird. I could only find that Metformin taken _together_ with
another BG-lowering medicin, it can cause a hypo.
Maybe Aspirin+Metformin dont go together.
I only know about taking insulin (lowers BG) + that I shouldnt take
Aspirin. Because of what?
Chance of hypo..
So ;-)
M.

[Ian Field]

"Maya Zuiderweg" <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote in

message news:HsudnZl9OO75QiXM...@giganews.com...

Going hypo probably isn't very likely, my Metformin was increased a few
months ago and I was warned that insulin looms on the horizon, but I've not
been retested since the increased metformin so I don't know anything for
sure.

[W. Baker]

Ian Field <gangprob...@ntlworld.com> wrote:


: "Maya Zuiderweg" <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote in

Metformin can cause intense gastsric distress, particularly when getting
used to it. That is why it is often only gradually ramped up to the full
dose. d I had problems with it after several yers, but ws put on the
extended release form and ws then able to take it , which I hae for over
16 years.

It does not cause hypos bocause it ony acts to slow the liver from putting
out glusoce stuff , not push out more insulin fromthe pancreas.

Wendy

[GysdeJongh]

W. Baker wrote:

> It does not cause hypos bocause it ony acts to slow the liver from
> putting out glusoce stuff , not push out more insulin fromthe
> pancreas.

uhh, are you sure you are not one of the scientific guys here ?

[Ian Field]

"W. Baker" <wba...@panix.com> wrote in message
news:kpaoak$cqt$1...@reader1.panix.com...

In this link it states a low risk of hypo;

http://en.wikipedia.org/wiki/Metformin

[Maya Zuiderweg]

GysdeJongh formuleerde op woensdag :

Sister Wendy is in disguise.
M.

[Maya Zuiderweg]

Het is zò dat Ian Field formuleerde :
>

Exactly what I found.
M.

[Julie Bove]

"Maya Zuiderweg" <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote in

message news:HsudnZl9OO75QiXM...@giganews.com...

I've had many hypos while on just Metformin. But then I can have a hypo on
no diabetes meds at all.

Daughter takes hers twice daily. One pill with breakfast and one with
dinner. Her breakfast is very light. Sometimes as little as a handful of
baby carrots. But that is changing. CDE impressed on her (apparently
better than I did) that she *must* eat some protein then.

[Maya Zuiderweg]

Het is zò dat Maya Zuiderweg formuleerde :

Ian!
I cant put links here, so I'll tell you where you may look and find
what youre after:
_Drugs That Can Affect Blood Glucose Levels_ . Put that in your
Google-bar, and hey presto all drugs are there for you!
M.

[GysdeJongh]

<http://diabetes.diabetesjournals.org/content/57/2/306.long>

Diabetes. 2008 Feb;57(2):306-14. Epub 2007 Oct 1.
Metformin inhibits hepatic gluconeogenesis through AMP-activated protein
kinase-dependent regulation of the orphan nuclear receptor SHP.

Metformin is an antidiabetic drug commonly used to treat type 2 diabetes.
The aim of the study was to determine whether metformin regulates hepatic
gluconeogenesis through the orphan nuclear receptor small heterodimer
partner (SHP; NR0B2). RESEARCH DESIGN AND METHODS: We assessed the
regulation of hepatic SHP gene expression by Northern blot analysis with
metformin and adenovirus containing a constitutive active form of
AMP-activated protein kinase (AMPK) (Ad-AMPK) and evaluated SHP, PEPCK, and
G6Pase promoter activities via transient transfection assays in hepatocytes.
Knockdown of SHP using siRNA SHP was conducted to characterize the
metformin-induced inhibition of hepatic gluconeogenic gene expression in
hepatocytes, and metformin-and adenovirus SHP (Ad-SHP)-mediated hepatic
glucose production was measured in B6-Lep(ob/ob) mice. RESULTS: Hepatic SHP
gene expression was induced by metformin,
5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranoside (AICAR), and Ad-AMPK.
Metformin-induced SHP gene expression was abolished by adenovirus containing
the dominant negative form of AMPK (Ad-DN-AMPK), as well as by compound C.
Metformin inhibited hepatocyte nuclear factor-4alpha-or FoxA2-mediated
promoter activity of PEPCK and G6Pase, and the inhibition was blocked with
siRNA SHP. Additionally, SHP knockdown by adenovirus containing siRNA SHP
inhibited metformin-mediated repression of cAMP/dexamethasone-induced
hepatic gluconeogenic gene expression. Furthermore, oral administration of
metformin increased SHP mRNA levels in B6-Lep(ob/ob) mice. Overexpression of
SHP by Ad-SHP decreased blood glucose levels and hepatic gluconeogenic gene
expression in B6-Lep(ob/ob) mice. CONCLUSIONS: We have concluded that
metformin inhibits hepatic gluconeogenesis through AMPK-dependent regulation
of SHP.
PMID: 17909097


Nature. 2013 Feb 14;494(7436):256-60. doi: 10.1038/nature11808. Epub 2013
Jan 6.
Biguanides suppress hepatic glucagon signalling by decreasing production of
cyclic AMP.

Glucose production by the liver is essential for providing a substrate for
the brain during fasting. The inability of insulin to suppress hepatic
glucose output is a major aetiological factor in the hyperglycaemia of
type-2 diabetes mellitus and other diseases of insulin resistance. For fifty
years, one of the few classes of therapeutics effective in reducing glucose
production has been the biguanides, which include phenformin and metformin,
the latter the most frequently prescribed drug for type-2 diabetes.
Nonetheless, the mechanism of action of biguanides remains imperfectly
understood. The suggestion a decade ago that metformin reduces glucose
synthesis through activation of the enzyme AMP-activated protein kinase
(AMPK) has recently been challenged by genetic loss-of-function experiments.
Here we provide a novel mechanism by which metformin antagonizes the action
of glucagon, thus reducing fasting glucose levels. In mouse hepatocytes,
metformin leads to the accumulation of AMP and related nucleotides, which
inhibit adenylate cyclase, reduce levels of cyclic AMP and protein kinase A
(PKA) activity, abrogate phosphorylation of critical protein targets of PKA,
and block glucagon-dependent glucose output from hepatocytes. These data
support a mechanism of action for metformin involving antagonism of
glucagon, and suggest an approach for the development of antidiabetic drugs.
PMID: 23292513

[GysdeJongh]

:)

[Ian Field]

"Maya Zuiderweg" <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote in

message news:_tSdnabUFOD1dCXM...@giganews.com...

Apparently Aspirin is among the list of drugs that can cause hypo- but I'd
have to dig a bit deeper to find if that's an interaction with an existing
prescription.

[Maya Zuiderweg]

Het is zￜ dat Ian Field formuleerde :

>
> "Maya Zuiderweg" <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote in
> message news:_tSdnabUFOD1dCXM...@giganews.com...

>> Het is zￜ dat Maya Zuiderweg formuleerde :
>>> Het is zￜ dat Ian Field formuleerde :

Metformin?
M.

[W. Baker]

Maya Zuiderweg <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote:
: GysdeJongh formuleerde op woensdag :

ALl the diabetes science I know I pretty much learned here and reading
diabetes in Control articles which i occaasionally post here.

I did take Geology and botany in College over 55 yers ago.

Wendy

[W. Baker]

GysdeJongh <JonghSevenHundredElevenAtPlanet.nl> wrote:

I just skimmed this is a few seconds. too dense a print for me to handle.
As far as I can see, it says what I did, only in a fancier way:-)

Sister Wendy

[GysdeJongh]

W. Baker wrote:
> GysdeJongh <JonghSevenHundredElevenAtPlanet.nl> wrote:

> I just skimmed this is a few seconds. too dense a print for me to
> handle. As far as I can see, it says what I did, only in a fancier
> way:-)
>
> Sister Wendy

+3.14 :)

[Andrew B. Chung, MD/PhD]

Ian Field wrote:

> Is there any reason a diabetic shouldn't use aspirin?

Diabetes is not a contraindication for aspirin.

> Thanks.

Laus Deo :-)

http://WDJW.net/LausDeo

Be hungrier, which really is wonderfully healthier especially for
diabetics and other heart disease patients:

http://www.11alive.com/news/article/251415/3/Doctor-Touts-Hunger (Luke
6:21a) with all glory to GOD, Who causes us to hunger (Deuteronomy
8:3) when He blesses us right now (Luke 6:21a) thereby removing the
http://WDJW.net/VAT from around the heart

...because we mindfully choose to openly care with our heart,

Andrew <><
--
Andrew B. Chung, MD/PhD
Emory's IMVC.org Cardiologist (GA Lic#040347)
and Author of the 2PD-OMER Approach:
https://groups.google.com/group/sci.med.cardiology/msg/e66adf59151b12b6?

[Colt T]

I take a low dose chewable aspirin with niacin to prevent flushing.

[Ian Field]

"W. Baker" <wba...@panix.com> wrote in message

news:kpatbf$hat$2...@reader1.panix.com...

Text presented like that is a bit too dry for most people.

[Ian Field]

"Maya Zuiderweg" <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote in

message news:LsqdndHKA4z4cSXM...@giganews.com...

I'm resisting the temptation to jump to conclusions till I've read a bit
more.

[Maya Zuiderweg]

Ian Field heeft ons zojuist aangekondigd :

>
> "Maya Zuiderweg" <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote in
> message news:LsqdndHKA4z4cSXM...@giganews.com...

>> Het is zò dat Ian Field formuleerde :

>>>
>>> "Maya Zuiderweg" <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote
>>> in message news:_tSdnabUFOD1dCXM...@giganews.com...

>>>> Het is zò dat Maya Zuiderweg formuleerde :
>>>>> Het is zò dat Ian Field formuleerde :

If I read you well you take the aspirin for bleeding better?
I have a suggestion: instead of the aspirin you can also take Omega 3
fishoil-softgels.
I took 2 of them per day, the dentist had a problem with my bleeding so
excessively. He asked if I took bloodthinners. I said: no.
When at home I remembered a posting here about Omega 3 fishoil capsules
(or softgels) being taken instead of Aspirin.

I made my mind up to take only _one_ softgel per day for 2 weeks (next
appointment).
Dentist was surprised: I did not bleed so terribly anymore, and the
dental works could go on.
M.

[Ian Field]

"Maya Zuiderweg" <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote in

message news:Z7adnSeJA6LWbyTM...@giganews.com...

> Ian Field heeft ons zojuist aangekondigd :
>>
>> "Maya Zuiderweg" <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote
>> in message news:LsqdndHKA4z4cSXM...@giganews.com...

>>> Het is zￜ dat Ian Field formuleerde :

>>>>
>>>> "Maya Zuiderweg" <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$>
>>>> wrote in message news:_tSdnabUFOD1dCXM...@giganews.com...

>>>>> Het is zￜ dat Maya Zuiderweg formuleerde :
>>>>>> Het is zￜ dat Ian Field formuleerde :

That's one of the things I do my best to avoid - but i am concerned about
circulation.

Blood like treacle doesn't flow very well in blood vessels thinner than
hair.

[Maya Zuiderweg]

W. Baker schreef :

> Maya Zuiderweg <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote:
>> GysdeJongh formuleerde op woensdag :
>>> W. Baker wrote:
>>>
>>>> It does not cause hypos bocause it ony acts to slow the liver from
>>>> putting out glusoce stuff , not push out more insulin fromthe
>>>> pancreas.
>>>
>>> uhh, are you sure you are not one of the scientific guys here ?
>
>> Sister Wendy is in disguise.
>> M.
> ALl the diabetes science I know I pretty much learned here and reading
> diabetes in Control articles which i occaasionally post here.

When I just got diagnosed my husband immediately buyed some books
(1981), these were a great help.
Then the Dutch diabetes group (which is out of use now).
More books.
Internet.
Diabc, the magazine from the DVN.

Last year April I came here.
Diabetes, like so many other chronic diseases, is never learned enough
about imo.

>
> I did take Geology and botany in College over 55 yers ago.

Dont think you can learn directly about diabetes from Botany or
Geology?

I took Art History, university of Amsterdam.
And studied flute and cembalo, but not at the university, its called:
Conservatorium. I think something like Juilliard? (sp)..
I have hyperacusis now, so no more concerts for me. Deaf on right ear +
tinnitus.
What I think one can learn from a study like Art History (or any other
long study?), is getting a kind of investigative mind. You learn to
think another way and take nothing for granted.

Maya



> Wendy

[W. Baker]

Maya Zuiderweg <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote:
: W. Baker schreef :

I ony took one course in Geology and one in Botany to satisfy athe science
requirement. My major ws aerican Historywith , of course related other
histories, economics, government, etc . My small amount of science was
the point of my remark about my not being the one to cite all kinds of
long studies I have difficulty seeing.

My daughter studied flute at Juilliard and my husband, trumpet long long
ago, graduating at 19 in 1940! Mydaughter gratuated much later:-) Syd
was a professional trumpet player and in mid life, also a secondary school
teacher of music days while playing Broadway shows at night(over 6 year as
first trumpet in "My Fair Lady." Music is a big part of my life too, but
as an spouse. mother and audience:-) sorry about your hearing. syd had
that problem in spades for the last 30 or so years of his life comination
of sitting in the pit with other oud brass players around him, genetics
and, finally an acoustic neuroma(benign, but sever) which cost him all
hearing in his "gd " ear overnight.

Wendy

[W. Baker]

Maya Zuiderweg <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote:
: Ian Field heeft ons zojuist aangekondigd :

: >
: > "Maya Zuiderweg" <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote in
: > message news:LsqdndHKA4z4cSXM...@giganews.com...

: >> Het is z? dat Ian Field formuleerde :

: >>>
: >>> "Maya Zuiderweg" <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote
: >>> in message news:_tSdnabUFOD1dCXM...@giganews.com...

: >>>> Het is z? dat Maya Zuiderweg formuleerde :
: >>>>> Het is z? dat Ian Field formuleerde :

I ake Metformin and a baby asprin evryday. No hypos.

Wendy

[Ian Field]

"W. Baker" <wba...@panix.com> wrote in message

news:kpd35m$q0o$3...@reader1.panix.com...

The main difference aspirin made for me is during blood tests - they don't
have to hack my arm to bits trying to find a vein they can draw blood from.

[Maya Zuiderweg]

W. Baker formuleerde de vraag :

I get that Wendy. What I dont (yet) understand is the word science.
Reading books about diabetes, that is not science, I mean.

>
> My daughter studied flute at Juilliard and my husband, trumpet long long
> ago, graduating at 19 in 1940! Mydaughter gratuated much later:-) Syd
> was a professional trumpet player and in mid life, also a secondary school
> teacher of music days while playing Broadway shows at night(over 6 year as
> first trumpet in "My Fair Lady." Music is a big part of my life too, but
> as an spouse. mother and audience:-)

Thats nice to read.

> sorry about your hearing. syd had
> that problem in spades for the last 30 or so years of his life comination
> of sitting in the pit with other oud brass players around him, genetics
> and, finally an acoustic neuroma(benign, but sever) which cost him all
> hearing in his "gd " ear overnight.

Very sad :/
I still try: soft (as in turning the volume down) music without flutes,
no high notes from violins or singers, no trumpets either.
Stringquartets, symphonies from e.g. Mozart etc etc.
I must watch out, because I am often enraptured by the music, but
afterwards (tells experience) I'm in a heck of a pain in both (!) ears.

Maya


> Wendy

[Maya Zuiderweg]

Na rijp beraad schreef Ian Field :

>
> "Maya Zuiderweg" <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote in
> message news:Z7adnSeJA6LWbyTM...@giganews.com...
>> Ian Field heeft ons zojuist aangekondigd :
>>>
>>> "Maya Zuiderweg" <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote
>>> in message news:LsqdndHKA4z4cSXM...@giganews.com...

>>>> Het is zò dat Ian Field formuleerde :

>>>>>
>>>>> "Maya Zuiderweg" <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote
>>>>> in message news:_tSdnabUFOD1dCXM...@giganews.com...

>>>>>> Het is zò dat Maya Zuiderweg formuleerde :
>>>>>>> Het is zò dat Ian Field formuleerde :

Then I understood wrong. I thought your concern was about wounds..
M.

[W. Baker]

Maya Zuiderweg <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote:
: Na rijp beraad schreef Ian Field :
: >
: >>>>>>
: >>>>>> Ian!

: >>>>>> I cant put links here, so I'll tell you where you may look and find
: >>>>>> what youre after:
: >>>>>> _Drugs That Can Affect Blood Glucose Levels_ . Put that in your
: >>>>>> Google-bar, and hey presto all drugs are there for you!
: >>>>>
: >>>>> Apparently Aspirin is among the list of drugs that can cause hypo- but
: >>>>> I'd have to dig a bit deeper to find if that's an interaction with an
: >>>>> existing prescription.
: >>>>
: >>>> Metformin?
: >>>
: >>> I'm resisting the temptation to jump to conclusions till I've read a bit
: >>> more.
: >>
: >> If I read you well you take the aspirin for bleeding better?
: >
: > That's one of the things I do my best to avoid - but i am concerned about
: > circulation.
: >
: > Blood like treacle doesn't flow very well in blood vessels thinner than hair.

: Then I understood wrong. I thought your concern was about wounds..
: M.

It sounds like Ian needs a blood thinner like asprin, which I never hears
of leading to hypos when paired with Metformin. Really, you should talk
to your MD about thisas here you just seem to be getting sawed bck and
forth by all kinds of peope with all kinds of contradictory advice. I
know what works for me, but your MD will know better what works for many
people as s/he deals with many peope .

Wendy

[bj]

"Ian Field" <gangprob...@ntlworld.com> wrote:
>
> The main difference aspirin made for me is during blood tests - they
> don't have to hack my arm to bits trying to find a vein they can draw blood from.
>

Have you also been sure to be very well hydrated before the blood draw?
That can often make a lot of difference in how easy it goes.
bj

[Bjørn Steensrud]

Fasting can also lead to low bg when the glucogen stores are empty -
maybe that's what happened to you?

[Ian Field]

"Maya Zuiderweg" <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote in

message news:CuCdnVojZb-3yyfM...@giganews.com...

> Na rijp beraad schreef Ian Field :
>>
>> "Maya Zuiderweg" <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote
>> in message news:Z7adnSeJA6LWbyTM...@giganews.com...
>>> Ian Field heeft ons zojuist aangekondigd :
>>>>
>>>> "Maya Zuiderweg" <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$>
>>>> wrote in message news:LsqdndHKA4z4cSXM...@giganews.com...

>>>>> Het is zￜ dat Ian Field formuleerde :

>>>>>>
>>>>>> "Maya Zuiderweg" <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$>
>>>>>> wrote in message
>>>>>> news:_tSdnabUFOD1dCXM...@giganews.com...

>>>>>>> Het is zￜ dat Maya Zuiderweg formuleerde :
>>>>>>>> Het is zￜ dat Ian Field formuleerde :

That was just another aspect - I tend to notice small injuries sooner when I
notice that I'm leaving blood traces on things I touch.

In any wound, some blood flow helps purge the wound and clear dirt/pathogens
etc - so that's 2 ways a bit of blood can help me manage infection risk more
effectively.

Having the nurse poke numerous holes in my arm every time I go for a blood
test was also something I could do without.

[Opple0påad]

On Mon, 10 Jun 2013 22:30:58 +0100, "Ian Field"
<gangprob...@ntlworld.com> wrote:

>Is there any reason a diabetic shouldn't use aspirin?
>
>Thanks.

I take a daily low dose aspirin per Endocrinologist's orders.

[Maya Zuiderweg]

Ian Field bracht volgend idée uit :

>
> "Maya Zuiderweg" <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote in
> message news:CuCdnVojZb-3yyfM...@giganews.com...
>> Na rijp beraad schreef Ian Field :
>>>
>>> "Maya Zuiderweg" <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote
>>> in message news:Z7adnSeJA6LWbyTM...@giganews.com...
>>>> Ian Field heeft ons zojuist aangekondigd :
>>>>>
>>>>> "Maya Zuiderweg" <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$> wrote
>>>>> in message news:LsqdndHKA4z4cSXM...@giganews.com...

>>>>>> Het is zò dat Ian Field formuleerde :

>>>>>>>
>>>>>>> "Maya Zuiderweg" <$no_spam#ma_dot_zuiderweg_@_me_dot_com#maps_on$>
>>>>>>> wrote in message news:_tSdnabUFOD1dCXM...@giganews.com...

>>>>>>>> Het is zò dat Maya Zuiderweg formuleerde :
>>>>>>>>> Het is zò dat Ian Field formuleerde :

I dont understand this. You leave bloodtraces...eek?

>
> In any wound, some blood flow helps purge the wound and clear dirt/pathogens
> etc - so that's 2 ways a bit of blood can help me manage infection risk more
> effectively.

Thats what I meant. So you DO want more bloodflow?

>
> Having the nurse poke numerous holes in my arm every time I go for a blood
> test was also something I could do without.

Same here. Until I began taking Omega3 softgels. I began taking it for
something different - the vampire nurse asked me the last time if I
took bloodthinners. I said: NO I DON'T (in Dutch;-).
Well, the same story as with my dentist..
M.