Description:
Support for sufferers of ulcerative colitis.
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Methotrexate as an HDAC inhibitor
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How much of methotrexate's benefits in cancer and autoimmunity are due to HDAC inhibition and how much due to dihydrofolate reductase inhibition? I wonder if EGCG also displays this same activity. Biochem Biophys Res Commun. 2009 Dec 21 Inhibition of histone deacetylase activity is a novel function of the... more »
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Dangers of Ileostomy Leakage and Epidural
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I wanted to bring this article to your attention, which highlights the dangers of sepsis from an ill-fitting ileostomy bag when having an epidural for pain relieve. There are a handful of patients here with ileostomies and I, for one, have had a few epidurals in the last 17 years that I have been... more »
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HDAC1 upregulation in neurodegneration impairs neuronal mitochondrial transport
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This points to a defective OCTN2/carnitine/butyrate uptake mechanism which perhaps accounts for the gender bias in multiple sclerosis. Testosterone is a carnitine transporter and given how the movement of mitochondria is vital in neurotransmission, this might help link testosterone and NGF signaling. In any case, it points to butyrate as... more »
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About Laproscopic Surgery
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The Journey towards Surgical cure is not always a pleasant one. Apprehension towards pain and post-operative morbidity and complications are always on the minds of the patient and his near and dear ones. It is a physical, social and financial burden on all concerned. The process is equally stressful for the medical personnel involved.... more »
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The Surge Group
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The Journey towards Surgical cure is not always a pleasant one. Apprehension towards pain and post-operative morbidity and complications are always on the minds of the patient and his near and dear ones. It is a physical, social and financial burden on all concerned. The process is equally stressful for the medical personnel involved.... more »
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Ghrelin enhances brain's reward machinery
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<[link]> Why Some Continue to Eat When Full: Researchers Find Clues ScienceDaily (Dec. 28, 2009) ‹ The premise that hunger makes food look more appealing is a widely held belief -- just ask those who cruise grocery store aisles on an empty stomach, only to go home with a full... more »
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