what is the difference between all the aminosalicylates??
David
colazal?? How does one know which is the best one to take??
Howard Jarrett
But I might could shed some light on the others.
'mesalamine' is the actual antiinflamatory that is delivered to the
intestines.
'Sulfasalazine' was the first developed. It combined sulfa with mesalazine.
This allowed the combined chemical to survive the trip through the acids of
the stomach. After the stomach it would break down into the two parts.
Because of the number of patients who were alergic to sulfa several other
drugs were developed which delivered pretty much the same mesalazine, but
without the sulfa.
Asacol, Pentasa & Colazal
I just looked it up on the CCFA site, and it described it a little different
than I had understood. Check there.
http://www.ccfa.org/research/info/medications
They list three 5-ASA drugs: olsalazine, mesalamine & balsalazide.
Dipentum delivers the 5-ASA drug olsalazine.
Asacol & Pentasa deliver the 5-ASA drug mesalamine.
Colazal delivers the 5-ASA drug balsalazide.
I have been on sulfazalazine (could not tolerate it), Pentasa, and am now on
Colazal.
In addition to delivering pretty much the same 5-ASA anti-inflammatory drug
there are the following differences.
Pentasa begins to deliver mesalamine just after passing through the stomach,
and continues to deliver more as it travels through the small intestine and
colon.
Asacol begins to deliver mesalamine at the beginning of the colon.
Colazal begins to deliver balsalazide about half way through the colon.
Rowasa enemas deliver mesalazine from the other end and it reaches only the
lower part of the colon.
I hope I got this right - corrections are welcome.
Hopefully your dr will beable to fine the right drug for you - one that you
will tolerate & one that will be effective for reducing your inflammation.
Howard
UC since 1995
"David" <Da...@asdf.com> wrote in message
news:MPG.1c8fccd71...@news.east.earthlink.net...
Mike
sulfasalazine (2 molecules bound together and broken apart by the same
intestinal bacteria), but no sulfa. It's 30 years old, and still not
available in generic and almost never prescribed. Apparently, it has a
tendency to cause diarrhea. It did not do that for me.
Thanks,
Mike
annie
i was on dipentum years ago and it was not great for me...asacol has
been much better...
we tried both colazal and pentasa and neither did much...my doctor said
that a lot of it is trial and error with these...what works for one
doesnt work for the next...
dipentum did NOT cause diarrhea for me..it just didnt stop the problems
at all..and i was always on prednisone...
now i am on asacol, cipro and 6mp...no pred for a couple of years
now...hopefully never again...
take care..annie
Karen
addressed, too? I'm glad for you that you are off pred. I was in a
panic the other day thinking that was the next step for me, but I've
learned so much here in the past two days that I hope I can avoid it
for now and forever.
Karen
Carole Allen
mgbio
:) mgbio
mgbio
I don't know why Annie suggested Cipro to you (since you didn't quote her post), however, specific antibiotics such as Cipro, Flagyl, Rifamab and Biaxen have been shown to help control IBD and have their place in its treatment.
:) mgbio
Bruce
> Annie, why Cipro? Is there a bacterial agent that needs to be
> addressed, too?
Certain antibiotics have been proven to be useful for treating Crohn's
disease, particularly CD involving fistulas and abscesses. With the
possible exception of a bacterium called MAP(Mycobacterium avium
subspecies paratuberculosis) however there is currently not one
particular bacterium known or believed to be involved in the
pathogenesis of Crohn's.
Keep in mind that at the same time antibiotics have not been shown to be
effective in ulcerative colitis.
Howard Jarrett
"Carole Allen" <caro...@comcast.net> wrote in message
news:4226865...@news.individual.net...
Howard Jarrett
heard much about it, and it doesn't get talked about much on this newsgroup.
Don't know why.
Howard
"Mike" <hopita...@yahoo.com> wrote in message
news:1109806565.4...@z14g2000cwz.googlegroups.com...
virginia
virginia
experienced no side effects). I recently switched to Asacol &
Methotrexate injections and the side effects between the two are so
terrible that i'd almost rather deal with the chron's flareups. i am
nauseated all of the time, with my ears ringing and general fluish type
feelings. Also very fatigued and keep a headache. Has anyone else had
this combination of meds and these side effects?
Mike
don't know why asacol was so toxic to me, but it was....
Thanks,
Mike
Sdores
have a remission from it. I don't know why but I will take it! Glad you are
feeling better. UM MOM Susannews:1109984489.1...@l41g2000cwc.googlegroups.com...
Jeff
months there was no real change in my symptoms. Then I cut back on some
supplements and eventually stopped taking the Cipro. Within about 6 weeks I
was having a pretty bad flare and thought I was headed for some serious
medical intervention. But before I did that I started back on the
medications and in about 4 weeks things had improved. But not to the point
where I wanted to be. So I made some dietary modifications and went back on
all of the supplements I was on when I was doing my best.
Since then I have improved considerably. So I feel that for me it's a
combination of the right things that is the most effective. The right meds,
diet, supplements, and exercise seems to improve my condition better than
any single part.
tx
Jeff
"annie" <anniel...@yahoo.com> wrote in message
news:1109817879.3...@l41g2000cwc.googlegroups.com...
Jeff
be delivered in the colon and you have CD. It's possible the side effects
were the result of the drug acting in a place where is was not needed.
In a recent post it is clear that the colon does more than previously
thought. I helps in vitamin production and absorption and electrolyte
absorption. Hindering this process could result in other symptoms. In Asian
medical practices they developed a keen awareness of how different symptoms
affect the body in many ways. Often times what my seem like disparate
symptoms are actually related. Ringing in the ears is said to be sometimes
related to kidney functions. It may seem strange at first but if you think
about it whether the kidneys are doing their job or not can effect
substances in the blood and also possibly in the lymphatic system. Blood
circulates throughout the body and the ears are particularly sensitive piece
of mechanics.
But beyond just making these connections they have developed treatment
principles that really work. So it's not just an interesting theory. I
believe that many of the theories actually grew out of observation and
practice which then supported the creation of the theory.
regards,
Jeff
"Sdores" <sdo...@bellsouth.net> wrote in message
news:enhWd.989$Q83...@bignews5.bellsouth.net...
Mike (remove XX's to reply)
>
> In a recent post it is clear that the colon does more than previously
> thought. I helps in vitamin production and absorption and electrolyte
> absorption. Hindering this process could result in other symptoms. In Asian
> medical practices they developed a keen awareness of how different symptoms
> affect the body in many ways. Often times what my seem like disparate
> symptoms are actually related. Ringing in the ears is said to be sometimes
> related to kidney functions. It may seem strange at first but if you think
> about it whether the kidneys are doing their job or not can effect
> substances in the blood and also possibly in the lymphatic system. Blood
> circulates throughout the body and the ears are particularly sensitive piece
> of mechanics.
>
Jeff, I know that you've been doing a lot of research on tinnitus! ;-)
It makes a lot of snese on many different levels. Do you know what is
the predominant electrolye in the cochlear endolymph? Potassium! The
kidneys regulate potassium and salt. Too much of one, means not enough
of the other. Mess those up, and your ears will not be happy! I won't
even being to talk bout fluid buildup.
Thanks,
Mike