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Research: (conference presentation) New research identifies possible risk factors, treatments for bowel

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zumone2002

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May 21, 2012, 11:51:06 PM5/21/12
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http://www.eurekalert.org/pub_releases/2012-05/ddw-nri051812.php

High-Altitude Journeys and Flights Are Associated with the Increased
Risk of Flares in IBD Patients (Abstract #303)

Hormonal Replacement Therapy and Risk of Ulcerative Colitis and
Crohn's Disease Among Postmenopausal Women: Results from a Large
Prospective Cohort of U.S. Women (Abstract #401)

Reproductive Factors and Risk of Ulcerative Colitis and Crohn's
Disease: Results from Two Large Prospective Cohorts of U.S. Women
(Abstract #402)

PIANO: A 1000 Patient Prospective Registry of Pregnancy Outcomes in
Women with IBD Exposed to Immunomodulators and Biologic Therapy
(Abstract #865)

--
Luke

Its Digestive Disease Week 2012
conference proceedings are interesting but have typically not
undergone peer review

Rufus

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May 22, 2012, 12:46:20 AM5/22/12
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zumone2002 wrote:
> http://www.eurekalert.org/pub_releases/2012-05/ddw-nri051812.php
>
> High-Altitude Journeys and Flights Are Associated with the Increased
> Risk of Flares in IBD Patients (Abstract #303)
> undergone peer review

...so much for my pilot's and skydiving licenses!

--
- Rufus

Jeff

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May 23, 2012, 8:26:56 PM5/23/12
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I found this snippet very interesting...

------------------------------------------------
Environmental Risk Factors for Crohn's Disease: Maltodextrin (MDX), a
Ubiquitous Dietary Additive in Western Diets, Enhances Biofilm Formation
and Adhesivness of E. coli (Abstract #Tu1844)

Western diets that include significant amounts of the additive
maltodextrin, a filler compound added to the sweeteners Splenda and
Equal, may contribute to an increased susceptibility to Crohn's disease,
according to new research from the Cleveland Clinic Lerner Research
Institute, OH. There is a clear link between bacteria and inflammatory
bowel disease (IBD), with previous studies reporting differences in the
types of bacteria and location of bacteria in the intestines of
individuals with Crohn's disease.

Investigators led by Christine McDonald, PhD, assistant staff,
pathobiology department, Lerner Research Institute, looked at how
bacteria were altered by components of the Western diet to better
understand how diet affects bacteria associated with IBD, an area of
research not well understood. They reviewed how certain components of
this diet alter E. coli bacteria to increase their ability to form
biofilms and adhere to intestinal epithelial cells — features associated
with the disease.
-----------------------------------------------------------------

especially this statement...

"how bacteria were altered by components of the Western diet to better
understand how diet affects bacteria associated with IBD, an area of
research not well understood."

Well at least they are finally asking those questions, but good God it
took them long enough.
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