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Biphosphonates and Protection from Breast Cancer
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James Howard
Dec 14, 2009, 5:10:10 PM12/14/09
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It is my hypothesis that low DHEA may cause breast cancer, and other
cancers, (Annals of Internal Medicine 2005; 142: 471-472). It is known that
prolactin directly and specifically increases DHEA production. I suggest
that this is part of a cyclical mechanism in which prolactin is secreted to
stimulate DHEA production and that subsequent DHEA production reduces
prolactin production to control secretion of DHEA.
cancers, (Annals of Internal Medicine 2005; 142: 471-472). It is known that
prolactin directly and specifically increases DHEA production. I suggest
that this is part of a cyclical mechanism in which prolactin is secreted to
stimulate DHEA production and that subsequent DHEA production reduces
prolactin production to control secretion of DHEA.
It is known that biphosphonates reduce hyperprolactinemia. I suggest
biphosphonates may reduce prolactin production by stimulating DHEA, which is
also known to increase bone production. I am saying that I think the
positive effects of biphosphonates, and other positive effects of
biphosphonates, are caused by an increase in DHEA. The increase in DHEA
reduces prolactin and increases bone.
I suggest the connection of reduced breast cancer in women taking
biphosphonates is increased DHEA.
James Michael Howard
Fayetteville, Arkansas, U.S.A.
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