Fruit And Vegetable In Asthma

[ironjustice]

"Only after increased fruit and vegetable intake"

Manipulating antioxidant intake in asthma: a randomized controlled
trial
Wood LG, Garg ML, Smart JM, Scott HA, Barker D, Gibson PG
American Journal of Clinical Nutrition (Aug 2012)

BACKGROUND: Antioxidant-rich diets are associated with reduced asthma
prevalence in epidemiologic studies. We previously showed that short-
term manipulation of antioxidant defenses leads to changes in asthma
outcomes.
OBJECTIVE: The objective was to investigate the effects of a high-
antioxidant compared with those of a low-antioxidant diet, with or
without lycopene supplementation, in asthma.
DESIGN: Asthmatic adults (n = 137) were randomly assigned to a high-
antioxidant diet (5 servings of vegetables and 2 servings of fruit
daily; n = 46) or a low-antioxidant diet (≤2 servings of vegetables
and 1 serving of fruit daily; n = 91) for 14 d and then commenced a
parallel, randomized, controlled supplementation trial. Subjects who
consumed the high-antioxidant diet received placebo. Subjects who
consumed the low-antioxidant diet received placebo or tomato extract
(45 mg lycopene/d). The intervention continued until week 14 or until
an exacerbation occurred.
RESULTS: After 14 d, subjects consuming the low-antioxidant diet had a
lower percentage predicted forced expiratory volume in 1 s and
percentage predicted forced vital capacity than did those consuming
the high-antioxidant diet. Subjects in the low-antioxidant diet group
had increased plasma C-reactive protein at week 14. At the end of the
trial, time to exacerbation was greater in the high-antioxidant than
in the low-antioxidant diet group, and the low-antioxidant diet group
was 2.26 (95% CI: 1.04, 4.91; P = 0.039) times as likely to
exacerbate. Of the subjects in the low-antioxidant diet group, no
difference in airway or systemic inflammation or clinical outcomes was
observed between the groups that consumed the tomato extract and those
who consumed placebo.
CONCLUSIONS: Modifying the dietary intake of carotenoids alters
clinical asthma outcomes. Improvements were evident only after
increased fruit and vegetable intake, which suggests that whole-food
interventions are most effective. This trial was registered at
http://www.actr.org.au as ACTRN012606000286549.


Who loves ya.
Tom


Jesus Was A Vegetarian!
http://tinyurl.com/634q5a


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