hello I'm new
Teresa
knee drained. He said only 35 percent of children with JRA go on into
the adult form. He wants to put me on plaquenil. I take celebrex now
and it works wonders but some times it's just not enough. I'd like to
hear some of your experiences with this drug. Like side effects and
what not.
greenknees
amcgr
for a couple of years, and suffered no side effects. You DO have to have
your eyes checked by an ophthalmologist on a regular basis, however. In a
very small number of cases, Plaquenil has a bad effect on your eyes. It
didn't bother my eyes. (It didn't help my arthritis, either!). I'm now on
Arava and Prednisone.
You can find lots of good information at www.arthritisinsight.com.
There are a couple of other sites to check out - somebody will surely
provide the links.
What part of the world do you live in? Are you working? Family? Pets?
Hobbies? Bad habits?
Cindy R.
(and NO mention of chocolate! So THERE!)
(not you, Teresa.....the rest of this bunch. They accuse me of trying to
wheedle chocolate out of newcomers. Not true. Absolutely not true. Your
chocolate is safe with me. Mmmmmm).
"Teresa" <bla...@zoomnet.net> wrote in message
news:3597181c.02030...@posting.google.com...
Maybull2
>(not you, Teresa.....the rest of this bunch. They accuse me of trying to
>wheedle chocolate out of newcomers. Not true. Absolutely not true. Your
>chocolate is safe with me.
Cindy you are incorrigible!!! LOL
Char
"Remember, I'm pulling for ya'.
We're all in this together." Red Green
Nann Bell
(in message <3597181c.02030...@posting.google.com>):
Plaquenil is a very mild DMARD. Very few side effects, and they are
reversible when you quit the drug. The key thing to worry about is geting
your eyes checked every 6 months because it can build up around the retina
and afect your eyesight (this is very rare, but should you be the rare one,
you want it caught early). It doesn't work at all for some folks, others do
very well with it. I have PA rather than RA but it worked nicely for me for
about 5 months - which is as long as anything has worked for me (so far).
Good Luck with it.
Nann
cut the Gator cheer to email me
I like nonsense; it wakes up the brain cells. - Dr Seuss
Lou
effective for me and I've moved on to the stronger DMARDS... MTX to be
exact. I have eye checkups every few months, including a visual fields test
and so far I haven't had any problems.
Lou
"Nann Bell" <afnGOGAT...@afn.org> wrote in message
news:01HW.B8B111E30...@news.earthlink.net...
: On Sat, 9 Mar 2002 18:36:14 -0500, Teresa wrote
:
:
:
:
watchman
Excess iron has been closely related to arthritis. Hundreds of hits in
Medline when 'iron and joints' used as search.
Vegetarian diet recommended.
Chelators of iron and antioxidants/ antirust supplements used with
significant improvement in symptoms.
[INLINE] TEKTRAN
_________________________________________________________________
IRON DEPOSITION IN THE JOINTS OF CHILDREN WITH JUVENILE RHEUMATOID ARTHRITIS
Author(s):
SHYPAILO ROMAN J
ELLIS KENNETH J
PEREZ MARIA
ABRAMS STEVEN A
Interpretive Summary:
We wanted to develop an accurate and noninvasive way of
determining the amount of iron deposited in the joints of
patients with juvenile rheumatoid arthritis. Children with JRA
often develop excess iron in their joints, so doctors need a
way of monitoring the iron level, particularly when prescribing
iron supplements for the common problem of anemia. However, the
only method currently available is to take a biopsy. We adapted
a machine called a gamma counter to measure the iron in eight
patients' joints after giving them an iron isotope by vein.
Then we compared the results with the total amount of iron in
their bodies, measured by a whole-body counter. We found that
we had developed an accurate new way of measuring iron in these
patients' joints. We also found that six of the eight subjects
had excess uptake of the iron isotope in their joints. That
provided a signal that a preponderance of JRA patients are
prone to have this problem, and clinicians should take special
care to monitor them for it. Moreover, this is the first time a
noninvasive way of performing this measurement has been
available.
Keywords:
energy reproduction growth body composition women infants
children water potassium bioelectrical impedance conductance
bromide space lactating iron adipose tissue lipid motabolism
beta-adrenergic receptor cell culture neutron activation
nitrogen carbon calcium sodium chlorine phosphorus hormonal
changes differentiation adipocyte hnrim021125
Contact:
USDA/ARS CHILDREN'S NUTR
1100 BATES ST.
HOUSTON
TX 77030
FAX: (713)798-7130
Email: kel...@bcm.tmc.edu
Approved Date: 1999-01-07
______________________________________________________________________
TEKTRAN
United States Department of Agriculture
Agricultural Research Service
Updated: 1999-01-16
Biochem Pharmacol 2001 Sep 15;62(6):743-6
Oxidative stress in rheumatoid arthritis leukocytes: suppression by rutin and
other antioxidants and chelators.
Ostrakhovitch EA, Afanas'ev IB
Russian State Medical University, Ostrovityanova 1, 117513, Moscow,
Russia.
The enhanced production of superoxide ion and peroxynitrite by
bloodstream neutrophils and of superoxide ion by monocytes from
rheumatoid arthritis (RA) patients was registered. It was suggested
that NADPH oxidase together with NO synthase were the major sources of
superoxide ion in RA neutrophils, while in RA monocytes superoxide ion
was produced by NADPH oxidase and mitochondria. Among the different
free radical inhibitors studied (antioxidant enzymes, SOD and
catalase; free radical scavengers, bioflavonoid rutin and mannitol;
and the iron chelator desferrioxamine), SOD and rutin were the most
efficient suppressors of oxygen radical overproduction by RA
neutrophils, while mannitol and desferrioxamine were inactive. Thus,
in contrast to Fanconi anemia (FA) leukocytes (Korkina LG et al., J
Leukocyte Biol 1992;52:357-62), iron-catalyzed hydroxyl radical
formation was unimportant in RA leukocytes, which mainly produced
superoxide ion. Natural non-toxic bioflavonoid rutin (vitamin P)
inhibited oxygen radical overproduction in both RA and FA in an
equally efficient manner and therefore may be considered as a useful
supporting pharmaceutical agent for the treatment of "free radical"
pathologies.
PMID: 11551519, UI: 21435631
_________________________________________________________________
Save the above report in [Macintosh] [Text] format
Order documents on this page through Loansome Doc
_________________________________________________________________
Med Hypotheses 2001 Aug;57(2):258-75
Upregulation of lymphocyte apoptosis as a strategy for preventing and treating
autoimmune disorders: a role for whole-food vegan diets, fish oil and dopamine
agonists.
McCarty MF
Pantox Laboratories, 4622 Santa Fe St, San Diego, CA 92109, USA.
Induced apoptosis of autoreactive T-lymphocyte precursors in the
thymus is crucial for the prevention of autoimmune disorders. IGF-I
and prolactin, which are lymphocyte growth factors, may have the
potential to suppress apoptosis in thymocytes and thus encourage
autoimmunity; conversely, dietary fish oil rich in omega-3 fats
appears to upregulate apoptosis in lymphocytes. Since whole-food vegan
diets may downregulate systemic IGF-I activity, it is proposed that
such a diet, in conjunction with fish oil supplementation and
treatment with dopamine agonists capable of suppressing prolactin
secretion, may have utility for treating and preventing autoimmune
disorders. This prediction is consistent with the extreme rarity of
autoimmune disorders among sub-Saharan black Africans as long as they
followed their traditional quasi-vegan lifestyles, and with recent
ecologic studies correlating risks for IDDM and for multiple sclerosis
mortality with animal product and/or saturated fat consumption.
Moreover, there is evidence that vegan or quasi-vegan diets are useful
in the management of rheumatoid arthritis, multiple sclerosis, and
possibly SLE. The dopamine agonist bromocryptine exerts
anti-inflammatory effects in rodent models of autoimmunity, and there
is preliminary evidence that this drug may be clinically useful in
several human autoimmune diseases; better tolerated D2-specific
agonists such as cabergoline may prove to be more practical for use in
therapy. The moderate clinical utility of supplemental fish oil in
rheumatoid arthritis and certain other autoimmune disorders is
documented. It is not unlikely that extra-thymic anti-inflammatory
effects contribute importantly to the clinical utility of vegan diets,
bromocryptine, and fish oil in autoimmunity. The favorable impact of
low latitude or high altitude on autoimmune risk may be mediated by
superior vitamin D status, which is associated with decreased
secretion of parathyroid hormone; there are theoretical grounds for
suspecting that parathyroid hormone may inhibit apoptosis in
thymocytes. Androgens appear to up-regulate thymocyte apoptosis, may
be largely responsible for the relative protection from autoimmunity
enjoyed by men, and merit further evaluation for the management of
autoimmunity in women. It will probably prove more practical to
prevent autoimmune disorders than to reverse them once established; a
whole-food vegan diet, coupled with fish oil and vitamin D
supplementation, may represent a practical strategy for achieving this
prevention, while concurrently lowering risk for many other
life-threatening 'Western' diseases. Copyright 2001 Harcourt
Publishers Ltd.
PMID: 11461185, UI: 21354746
_________________________________________________________________
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_________________________________________________________________
Who loves ya.
Tom
--
Jesus was a Vegetarian! http://www.nucleus.com/watchman
Moses was a Mystic! http://www.nucleus.com/watchman/light.html
Teresa
The doctor did seem very concerned about my eyes.
I am in northern Illinois.
I am a stay at home mom of two little girls.
3 cats. :)
My hobbies are collecting dawn dolls and painting
http://community.webshots.com/user/greenknees
no bad habits.
And you'll never get chocolate out of me, no sir, it's mine all mine.
greenknees
"amcgr" <am...@rogersnospam.com> wrote in message news:<SGzi8.65441$xG.4...@news2.bloor.is>...
dan etcheto
watchman wrote:
>
>
> Excess iron
Mary Zuschlag
@zoomnet.net says...
Hey fun pics! Your dolls had some pretty wild do's green and blue, fun and I
enjoyed your flower paintings. Now there is one rule here... no hoarding
chocolate so time to share all your dove chocolate. I like the semi-sweet
kind, you have it. I can see you trying to hide it...tsk tsk.
I have been on plaquenil for about 6 years without any problems. No problems
with my eyes but my Optho says he sees about 3 patients a year that have to
stop taking the drug due to eye problems. I had headaches when I first
started but they went away after I was on the drug for a while. It has the
nice side effect of lowering cholesterol! It takes a long time to work so
give it at least 3-4 months, for some folks it takes even longer. Welcome! --
MZ
--
visit my website:
http://www.mzuschlag.com
Reply to mzuschlag at attbidotcom
Maybull2
started. Love it.
Teresa
dumb question: what does "DMARD" mean?
Nann Bell
Oooooops, sorry - DMARD stands for Disease Modifying Anti-Rheumatic Drugs -
it refers to the drugs that actually interrupt the disease process rather
thanmerely treating the symptons of the disease.
NSAIDs - Non-Steriodal Anti-Inflammatory Drugs - is another acronym you see
here a lot. That's what the Celebrex is. These are used to knock down the
inflammation and, hopefully, the pain some, but they do not actually affect
the disease process and oint damage is usually ongoing even if the pain is
better.
Not at all a dumb question. Someone will be along soon with a link to a list
of the common abreviations here. I don't have it handy.
Mary
> _________________________________________________________________
>
>IRON DEPOSITION IN THE JOINTS OF CHILDREN WITH JUVENILE RHEUMATOID ARTHRITIS
Yellow-billed magpies are found only in central California. Does
living in California cause a yellow bill?
Hashimoto's thyroid disease is found more often in people with RA than
in people with no other autoimmune diseases. Does RA cause Hashimoto's
disease?
Correlation is not the same thing as causation.
Please pick up some basic science before continuing.
Just for fun, folks, do a search on groups.google.com for the words
"iron" and "watchman." See what else iron supposedly causes.
-
Mary MacT
http://www.prado.com/~iris
(new site under construction: http://www.alamedacreek.net/mary)
Teresa
Teresa aka greenknees
Nann Bell <afnGOGAT...@afn.org> wrote in message news:<01HW.B8B239420...@news.earthlink.net>...
Maybull2
>
There is no such thing as a dumb question. (Although we get some pretty stupid
spammers through here on occasion. Avoid ironboy at all costs.) Disease
modifying anti rheumatic drug.DMARD