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BP and Paracetamol

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ConnieD.

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Nov 2, 2002, 8:35:37 PM11/2/02
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Anyone read the article on the BBC the other day regarding the possible
relationship of Hypertension to Paracetamol?
There was some report about Americans who use Tylenol(sp) as their pain
relief and high blood pressure..... just wondering because I almost live on
paracetamol and have hypertension.
Regards ConnieD.

Pike@firewall.barrier Charles Pike

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Nov 6, 2002, 2:53:19 AM11/6/02
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"ConnieD." <Con...@fsnet.co.uk> wrote in message
news:3dc47...@news2.vip.uk.com...

It is not good to " almost live on Paracetamol" for even in medium overdoses
they are quite harmful to the kidneys, which could be a reason why they may
be thought to elevate blood pressure.

From what I have read, those who overdose on Parecetamol normally die
through associated kidney failure, and as I recall, about 18 tablets is
sufficient to cause such a death.

Why not intermit with some other pain killer, which does not contain
Paracetamol.

Charles.


Lee Thompson-Herbert

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Nov 6, 2002, 6:45:41 AM11/6/02
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In article <ZT3y9.200$Ua5....@newsfep1-win.server.ntli.net>,
Charles Pike <Charles Pi...@firewall.barrier> wrote:
[...]

>From what I have read, those who overdose on Parecetamol normally die
>through associated kidney failure, and as I recall, about 18 tablets is
>sufficient to cause such a death.

No, liver failure, and it's not a pretty death. Aspirin causes death
by kidney failure (and it's still an extremely common form of poisoning
in children).

Paracetamol poisoning takes about 48 hours to set in, if it's taken as one
big overdose. Kidney damage and high blood pressure are both things you'd
see when the dose is high over a long period of time. That can happen long
before liver damage when you're looking at _long term_ dosing. Taking 18
tablets would kill you from liver failure, if you weren't given acetylcysteine
in the first 12 hours or so after the overdose.

--
Lee M.Thompson-Herbert l...@retro.com KoX 1995, SP4
Head Muso, White Rats Morris, Faultline Morris
Member, Knights of Xenu (1995). Chaos Monger and Jill of All Trades.
"A head-on collision between Morticia Adams and Martha Stewart"

Nann Bell

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Nov 6, 2002, 10:30:01 AM11/6/02
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> No, liver failure, and it's not a pretty death. Aspirin causes death
> by kidney failure (and it's still an extremely common form of poisoning
> in children).

when I worked on the GI floor of a hospital, we had a patient who
self-treated a toothache over a holiday weekend with Tylenol and beer. She
came to us in liver failure and for about 3 weeks it was nip and tuck as to
whether she'd need a liver transplant. Fortunately her liver began to
regenerate.

I'm really careful of my liver because of all I saw when working there. The
Vicodin I took for my tooth abscess made me really leary on top of my mtx and
Arava. As Lee says, it doesn't take much of the acetaminophen/paracetamol to
do in the liver.


--
Nann
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It is the mark of an educated mind to be able to entertain a thought without
accepting it. - Aristotle

ConnieD.

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Nov 7, 2002, 6:28:12 AM11/7/02
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"Charles Pike" <Charles Pi...@firewall.barrier> wrote in message
news:ZT3y9.200$Ua5....@newsfep1-win.server.ntli.net...
Thanks for your response Charles. as for me and pain killers, due to a
severe intolerance to anything remotely Aspirin or Salycilate based ( I go
into anaphylactic shock) I am *stuck* with either paracetamol, 4000mg max a
day or codiene, 120mgs max a day, neither of which I relish but during
severe pain time, they are better than being on a life support machine....
( BTW I don't take the painkillers at max dosage and some days take nothing
at all)
Most of the regulars already know I have tried almost all of the NSAID's and
some of the DMARDS available but due to either the aspirin or difficulties
with other side effects am left in the situation of pain or the paracetamol.
I know from others that I am not alone with being able to use only
paracetamol but I do have frequent kidney/liver tests to make sure those
organs are not being compromised.
It would be lovely if someday there was a medication that didn't cause other
problems in trying to control the main one.
Regards ConnieD.


Alan White

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Nov 8, 2002, 3:09:46 AM11/8/02
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"ConnieD." <Con...@fsnet.co.uk> wrote in message
news:3dca4...@news2.vip.uk.com...
Hi, I take 16-20 Paracetamol a day the drug is solphadol the combination is
500/30 Paracetamol / Codeine I have gradually built up over the years I'm
trying to cut down my doctor recently found out I was getting so many
repeats he said I need to cut down he has now decided to give me them
separately.

AL


ConnieD.

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Nov 8, 2002, 5:25:22 AM11/8/02
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"Alan White" <No-emai...@hotmal.com> wrote in message
news:aoKy9.149$FJ2....@newsfep2-win.server.ntli.net...
Hiya Alan, I would also be very worried about the amount of para/codiene you
are taking too. Good luck ith coming off it and see if there are any other
alternative treatments such as hydrotherapy/physio/manipulation available to
you. Have you discussed atending a pain management clinic at all with your
GP?

I used to attend one in Holland and it was wonderful, ( I thought it would
all be about thinking yourself out of pain and deep breathing things but it
wasn't). I received pain blocking injections into my neck and they were the
best thing since sliced bread in my case ( they don't half smart at first
though <g>).
It has to be better than taking all the pain killers you are swallowing
though so perhaps you might want to have a chat with either your GP or
Rheumy.
Let us know how you are getting on though won't you?
Regards ConnieD

Alan White

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Nov 8, 2002, 7:55:05 AM11/8/02
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"ConnieD." <Con...@fsnet.co.uk> wrote in message
news:3dcb9...@news2.vip.uk.com...

Connie I don't like having to take them but I have had the pain for 15 years
now each year the dose increases - I am trying to cut down but its now abit
of a habit - I don't feel comfortable without them I also receive severe
headaches - my GP (in england) isn't really bothered I have had a couple of
run ins with him. I think I am in his way the government in england treat
doctors as if they are god - I don't - they are suppose to there for help
and support but the days of the Florence nightingale days are well gone.

AL


Alan White

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Nov 8, 2002, 8:01:01 AM11/8/02
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Pike@firewall.barrier Charles Pike

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Nov 8, 2002, 9:03:48 AM11/8/02
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"Alan White" <No-emai...@hotmal.com> wrote in message
news:wFOy9.360$o%5.65878@newsfep2-gui...

> Connie I don't like having to take them but I have had the pain for 15
years
> now each year the dose increases - I am trying to cut down but its now
abit
> of a habit - I don't feel comfortable without them I also receive severe
> headaches -

Paradoxically such headaches, I understand, can be a side effect of
overdosing or consuming too much of these normally helpful products.

Charles.


Alan White

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Nov 8, 2002, 1:19:54 PM11/8/02
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"Andy" <andyN...@ntlworld.com> wrote in message
news:fhnnsus74dhufg8lb...@4ax.com...

> On Fri, 8 Nov 2002 12:55:05 -0000, "Alan White"
> <No-emai...@hotmal.com> wrote:
>
> >Connie I don't like having to take them but I have had the pain for 15
years
> >now each year the dose increases - I am trying to cut down but its now
abit
> >of a habit - I don't feel comfortable without them I also receive severe
> >headaches - my GP (in england) isn't really bothered I have had a couple
of
> >run ins with him.
>
> Have you tried another GP?
>
>
>
> Andy

most GPs are the same - gone are the florence nightingale days - they see
the money now - thats why they are in this job.

AL


ConnieD.

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Nov 10, 2002, 8:48:20 AM11/10/02
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"Alan White" <No-emai...@hotmal.com> wrote in message
news:wFOy9.360$o%5.65878@newsfep2-gui...
Alan get yerself a new GP for your Livers sake if nothing else lad!!!

You do know that taking paracetamol can cause headaches don't you? Maybe
that's why you are suffering from those but I am NOT a doctor.

No reflection on you personally Alan but until patients take a stance over
the treatment they receive from their medics then us lot will also be the
ones to lie back and take second best so as not to cause any ripples. You
only have one crack at life and being in pain wasn't in the birthing
contract I am sure!
For your own sake, go and see about a new GP, we have to stand up against
receiving second rate treatments. Have you thought about asking him for any
pain management courses, just point out to him that he might even save his
practice funds if you don''t keep coming back for repeat prescriptions! (
The thought of cash just might do the trick)!!
If he were my GP, then regardless of any past run-ins, I would want the best
for me and he certainly doesn't seem to be providing that.

Regards ConnieD.
BTW I have to say that my GP is one of the best I have ever had and is very
caring and supportive, not bad for a young 'un!!( Well he looks very young
to my aged eyes)!


Alan White

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Nov 10, 2002, 4:39:53 PM11/10/02
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"ConnieD." <Con...@fsnet.co.uk> wrote in message
news:3dce6...@news1.vip.uk.com...

Hi ConnieD thanks for your support I have had three GPs in the past 20 years
and all three were blaming me for my health problems I was mis-diagnosed in
the eighties. I knew fine well that my hip was giving me problems - I
thought GPs were the be all then, so I left it be, buying pain killers by
the boat load as I was working 24/7.

I have tried hard with my present GP but I know in the back of my mind he
dosen't have a clue about pain relief - I'm sorry that I come across as if I
don't like GPs but I have lost faith in them. I don't know your condition
but mines O/A of the hip my GP is now unable to help me I am waiting a hip
op. The reason I had a run in with my GP is because I did take a stance over
the medication he was giving me. I tried to explain to him that solid
medication dosen't help me - I end up with severe constipation and heartburn
he said "So what do you want me to do?".

Maybe with me having O/A these GPs are not trained in this so they don't
care.

AL


g.portman

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Nov 10, 2002, 6:06:15 PM11/10/02
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My G.P is young in my eyes Connie and I'm only 34!!!

You wanted to know how I was getting on with the HRT - well - not to bad
really - I can cope with the pain now and the joints generally are better.
The GP has put me on the constantly until February at a dose of 3 a day then
for March down to 2 1/2 and reduce it by 1/2 tablet per month until I'm
off them in the hope that my body will be fooled into making the correct
dose of hormone - I had to do it like this before when I had Natasha. I
don't think I realised how bad I was getting.

Finally after having all the weight gain and swelling with Mobic the GP has
put me onto Volterol and for the first time in 4 months I have been able to
lift the baby out of her cot in a morning and bring her downstairs for her
breakfast instead of Tim doing it. I ran up the stairs yesterday without
even thinking about it and I haven't done that in 5 years!!!!

I agree with the advice that you gave Alan - he needs a new GP but he needs
to be able to work out a program to come off the Paracetamol slowly
otherwise he will have the most severe mind blowing headache in the world -
I know I have been there. I have to deal with anti psychotic drugs every day
with my son and have to increase and decrease his daily dose in such minute
quantities, especially when he is coming of an old drug and onto a new one.
I find it helps to write down what you want and what you want to acheive by
this action - I find it helps to put things into perspective. It also helps
you to be more positive when you are in with the GP because he can see that
you have put some thought into it. Also it might help to book a 15 minute
appt. with the GP instead of the normal 5 minute one. You shouldn't feel so
rushed to say everything all at once and then neither should the GP feel
that he has to rush you - don't be afraid to say that you haven't finished
explaining.

I hope everything is ok with you Connie.

Gaynor

"ConnieD." <Con...@fsnet.co.uk> wrote in message

news:3dce6...@news1.vip.uk.com...


> BTW I have to say that my GP is one of the best I have ever had and is
very
> caring and supportive, not bad for a young 'un!!( Well he looks very young
> to my aged eyes)!
>

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