Cognition and Iron Loading
ironjustice
loading or aging by the type 4-specific phosphodiesterase inhibitor
rolipram in rats.
de Lima MN, Presti-Torres J, Garcia VA, Guimarães MR, Scalco FS,
Roesler R, Schröder N
Neuropharmacology 2008 Jun 21.
Increasing evidence indicates that iron deposition in the brain might
play a role in cognitive dysfunction associated with neurodegenerative
disorders and aging. Previous studies have not examined whether iron-
induced memory deficits can be attenuated by acute treatments with
memory-enhancing agents. Phosphodiesterase type 4 (PDE4) inhibitors
such as rolipram (ROL) ameliorate memory impairments in several rodent
models of amnesia and have been proposed as candidate cognitive-
enhancing drugs. Here we show that a single posttraining systemic
injection of ROL dose-dependently attenuates the impairment of memory
for novel object recognition (NOR) in rats given neonatal iron
loading, a model of iron-induced cognitive impairment. Posttraining
administration of ROL also recovered NOR deficits associated with
aging in rats. These findings provide the first evidence that
stimulation of an intracellular second messenger signaling pathway can
attenuate iron-induced memory impairment, and support the view that
PDE4 inhibitors might ameliorate cognitive dysfunction associated with
aging and neurodegenerative disorders.
Neuropharmacology [Neuropharmacology]
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
fer...@ironcity.com
especially its impact on problems of cognition.
Iron-deficient Infants Have Lower Cognitive Scores At 19 ...
http://www.sciencedaily.com/releases/2006/11/061107082729.htm
Also:
Impact of iron supplementation on cognitive functions in preschool and
school-aged children: the Indian experience
Article Abstract:
Iron deficiency is a common health problem among children living in
India. Approximately 60 percent of children under age three years and
44 percent between the ages of three and five years have low
hemoglobin levels. In iron deficiency, the hemoglobin concentration in
red blood cells is reduced, which prevents delivery of adequate
amounts of oxygen to body tissues. Previous research has suggested
that iron deficiency may cause children to perform poorly on cognitive
or mental tests. The authors report results from four studies of iron
supplementation using elemental iron in children of different ages.
There is that india again, it keeps popping up.
ironjustice
What you should do is include a study which shows .. iron
deficiency .. causes iron loading .. ?
Try that ..
Not .. iron .. deficiency ..
The article is about .. iron .. loading ..
Maybe you should start a thread about .. iron .. deficiency .. ?
Do you understand the difference between iron loading and iron
deficiency .. ?
Do ya .. ?
One .. there is PLENTY of iron .. the other .. there isn't supposed to
be ANY iron ..
You see the difference .. ?
Iron YES versus .. NO iron ..
Pretty easy to understand .. yes versus no ..
Use those well honed .. deductive skills ..
Neuropharmacology [Neuropharmacology]
Who loves ya.
Tom
fer...@ironcity.com
deficiency .. ?"
Yes, and the one has been shown to correlate with the other.
Would you suggest those indian mothers and their children with cognitive
problems have high iron loading? If iron causes all diseases/disorders
because people eat meat, what gives with them?
India just keeps popping up again and again when it comes to wquestions of
litttle or no meat intake and high levels of various diseases/disorders.
ironjustice
The thread is iron in brain leads to neurodegeneration ..
Your deduction skills leads you to .. pregnant .. Indian .. women ..
You may think in your brain .. you have something to contribute .. but
evidentally .. you .. don't ..
Find something to .. do ..
fer...@ironcity.com
Not according to the subject line, it is about cognition and iron loading;
which includes those cognition problems from low iron. Low iron is the
world's number one health problem, two among many many examples provided
you previously. Recall india? Little or no meat, low iron problem in
children and women leading to many cognition problems, world's highest
levels of diabetes and heart disease etc., a direct and specific
refutation of the iron causes all diseases because people eat meat notion.
Dead as a dodo.
Jesus ate a mediterranean diet.
ironj...@aol.com
or no meat, low iron problem in children and women leading to many
cognition problems, <<
Low iron .. ?
You mean they weren't low on anything else .. ?
They got really lucky when you think of the effects of starvation.
They could have been low in many different nutrients.
On Jul 19, 5:18 pm, ferr...@ironcity.com wrote: world's highest levels
of diabetes and heart disease etc., a direct and specific refutation
of the iron causes all diseases because people eat meat notion. <<
They have the highest blood iron levels of anybody.
They have high diabetes.
High iron is found in diabetes.
What you should be doing is trying to figure out WHY they have such a
high rate of iron overload and diabetes.
You won't listen to me .. so .. work at it .. boi.
Come back when you have .. dedeuced .. WHY .. "Asians have the highest
blood iron levels of any race in the world" ..
Don't ya .. think .. ?
Asking a loon on the internet .. really .. using .. logic .. is
kinda .. stupid.
Isn't it .. ?
And you ain't .. stupid ..
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
"The thread is iron in brain leads to neurodegeneration .."
fer...@ironcity.com
disease. Another says meat is the source of the iron. nd the last says
eating meat and the iron caused all diseases is punishment from God for
eating the meat.
In india we have little or no meat intake so what iron stores there are
are from plant sources. They have the world's highest levels of diabetes
and heart disease while at the same time children and women suffer from
low iron and resulting cognition problems. Two of the leggs are broken
and God cares little about such fool notions.
The iron notion is dead as a dodo.
ironjustice
fer...@ironcity.com
'projection' means.
ironj...@aol.com
You might want to get a good psychology source and see what the term
'projection' means. <<
Maybe what you should do is figure out why you and your ilk figure
iron doesn't cause oxidation .. that would be .. rust.
Why can't you admit that out loud there .. buddy .. ?
Why can't you admit ..
"it is obvious that age related iron accumulation will cause
oxidation" ..
You are on THIS thread .. for .. ?
Disruption ..
You tell people with age related brain .. palsy .. to .. "not bother
looking" .. WHEN .. you know full well iron reduction causes reversal
of .. palsy.
You kinda have alot of .. bad .. sht .. coming back to ya ..
Don't ya .. ferrous ..
Now read .. my .. lips ..
I will have no more of my participation in YOUR .. going to hell ..
so .. cease and desist your stupidity .. or .. subversion on MY ..
threads ..
It .. stupidity .. irks me .. man.
Actually both do ..
Paul T. Holland
"ironj...@aol.com" wrote:
>
> On Jul 20, 5:34 pm, ferr...@ironcity.com wrote:
> You might want to get a good psychology source and see what the term
> 'projection' means. <<
>
> Maybe what you should do is figure out why you and your ilk figure
> iron doesn't cause oxidation .. that would be .. rust.
you constantly try to claim that others don't think that Fe in blood can
or does create/contribute to an oxidative state - this claim by you is
simply not true -
so much of your difficulty comes from the insistence upon silly
euphemism - 'rust'; which is:
"Rust is a general term for a series of iron oxides, usually red oxides,
formed by the reaction of iron with oxygen in the presence of water or
air moisture.
Several forms of rust are distinguishable visually and by spectroscopy,
and form under different circumstances.
[1] Rust consists of hydrated iron(III) oxides Fe2O3搖H2O, iron(III)
oxide-hydroxide (FeO(OH), Fe(OH)3.
Rusting is the common term for corrosion of iron and its alloys, such as
steel.
Other metals undergo equivalent corrosion, but the resulting oxides are
not commonly called rust.
Given sufficient time, oxygen, and water, any iron mass eventually
converts entirely to rust and disintegrates.
The corrosion of aluminium is extremely slow because the resulting
aluminium oxide forms a conformal coating, which protects the remaining
aluminium. This process is known as passivation."
now, what is true of fe and blood is that:
"of the essential metallic elements, iron presents one of the most
difficult systems to study in terms of elementary steps at the
organism/environment and cell/plasma barriers."
it is the 'oxidant' characteristics that vary so widely and it is the
difference between your 'correlation' of disparate facts, and your
confusion between cause and effect that enhance the way your theories
are negatively received
you're just being silly and stubborn using the term 'rust' tom - and it
makes you the object of japery almost every time you go there.
aka_velcro
ALONE READ THE SHIT SPEWED FORTH BY HIM REPETITIVELY.
Tom= REALLY A HERMAPHRODITIC NEANDERTHAL THAT WILL NOT GO AWAY.
Jesus Was A Vegetarian! JESUS ATE FISH. HE ATE A MEDITERRANEAN DIET.
http://tinyurl.com/2r2nkh (WHY ARE YOU ADVERTISING THAT YOU HAVE A
TINY***, ARE A TINY LITTLE DUMBASS THAT WON'T GO
AWAY!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!)
Man Is A Herbivore! I AM MAN, I AM HUMAN, I EAT MEAT. MOST PEOPLE EAT
MEAT AND ARE NOT HERBIVORES!
http://tinyurl.com/4rq595 (WHY ARE YOU ADVERTISING THAT YOU HAVE A
TINY***, ARE A TINY LITTLE DUMBASS THAT WON'T GO
AWAY!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!)
DEAD PEOPLE WALKING. DEAD PEOPLE CANNOT TALK, WALK, OR EAT, REGARDLESS
OF THE BULLSHIT SWIMMING AROUND IN THAT FILTHY, SICK, ANNOYING HEAD OF
YOURS.
http://tinyurl.com/zk9fk (WHY ARE YOU ADVERTISING THAT YOU HAVE A
TINY***, ARE A TINY LITTLE DUMBASS THAT WON'T GO
AWAY!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!)
STAY OFF ANY THREADS.
HOW DO YOU OWN ANYTHING?
STAY OUT OF THE NEWSGROUPS.
QUIT POSTING NONSENSE THAT NO ONE WANTS TO HEAR.
THE ONLY PURPOSE YOU HAVE IN LIFE IS TO ANNOY THOSE ACTUALLY USING
THESE SERVICES FOR THE INTENDED PURPOSE BY POSTING YOUR SHIT.
QUIT.
YOU FIT THE PROFILE OF THE CYBERSTALKER, CYBERBULLY. YOU ARE THE ONE
and ONLY PERSON DOING THAT TO THE REST OF THE NEWSGROUP SUBSCRIBERS.
GO AWAY.
WHY CAN'T YOU UNDERSTAND THAT **YOUR POSTING IS NOT WANTED HERE*****
fer...@ironcity.com
'projection' means. <<
"Maybe what you should do is figure out why you and your ilk figure
iron doesn't cause oxidation .. that would be .. rust.
Why can't you admit that out loud there .. buddy .. ?
Why can't you admit ..
"it is obvious that age related iron accumulation will cause
oxidation" .."
One of your most striking weaknesses is to read into the thoughts and
motivations of others what you want to see, just like when you read and
post abstracts you do not comprehend.
Never was a statement made that iron does not oxidize.
Oxidation is the combining of any substance with oxygen, for a simple
definition. The brown color on an apple slice left in the open air is an
example with no iron involved. So iron does not cause oxidation, it like
many many substances can become oxidized.
"You are on THIS thread .. for .. ?
Disruption ..
"
Excuse me, please do consult what appears to be an invitation to respond
in the subject line. The original thread was about iron status and
cognition, to which I promptly made a contribution showing that in
addition to too much iron too little can also create cognition problems.
Sorry about the iron agenda being derailed.
ironj...@aol.com
wrote: long winded whack <<
Neuropharmacology [Neuropharmacology]
ironj...@aol.com
<<
Remember not to crush chew break or inject those meds
ironj...@aol.com
Sorry about the iron agenda being derailed. <<
No actually it was the .. buildup of iron in the brain of old
people ..
THAT was the derailment .. wasn't .. it ..
YOU .. bigman .. walk up to an old guy on the street who is so far fkg
gone .. and what .. ?
What did you .. try .. to do .. ?
Eh .. bigman ..
Heh .. heh ..
What is it called .. ?
Comeupance .. ?
Shtkckn .. is what we call it ..
Neuropharmacology [Neuropharmacology]
Who loves ya.
Tom
Jesus Was A Vegetarian!
http://tinyurl.com/2r2nkh
Man Is A Herbivore!
http://tinyurl.com/4rq595
DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk
fer...@ironcity.com
"No actually it was the .. buildup of iron in the brain of old
people ..
What is it called .. ?
Comeupance .. ?"
Now, now, don't be so hard on yourself. Now the iron notion is dead as a
dodo think how much of your time will be saved for getting your life back.
No, no, don't thank me. It is enough for me to know you are now on
another more productive track in your life.