more on vit D - lower dosage recommended
Dawid Michalczyk
"Researchers from the European Institute of Oncology in Milan, Italy,
and the International Agency for Research on Cancer in Lyon, France,
reviewed 18 trials of more than 57,000 people.
The trials involved doses of vitamin D ranging from 300 international
units (IUs) to 2,000 IUs. The average dose was 528 IUs.
After a period of six years, the data showed that people who took
vitamin D supplements had a 7 percent lower risk of death compared to
people who did not take the supplements.
Further, according to the nine trials that collected blood samples,
people who took vitamin D supplements had a 1.4- to 5.2-fold higher
level of vitamin D in their blood than those who did not.
Because vitamin D can reduce the proliferation of cells, which occurs in
cancer, the researchers believe their finding could lead to new drugs to
fight cancer and other illnesses.
Vitamin D also helps your body to uptake calcium for bone health.
The researchers recommend taking between 400 IUs and 600 IUs of vitamin
D daily. Your skin can also produce its own vitamin D by getting
moderate sun exposure each day."
--
Dawid
http://www.headache-migraine.net _Migraine headache information_
trigonom...@gmail.com
> The researchers recommend taking between 400 IUs and 600 IUs of vitamin
> D daily. Your skin can also produce its own vitamin D by getting
> moderate sun exposure each day."
>
Sure some repeat thosed dated recommendation and often it is
not the researcher but the reporter or some other supposed authority
providing background. Many now recommend 800 to 1000 IU.
Which is still too low but an improvement.
The 200, 400, and 600 recommendation is sorely dated.
bigvince
Hi first the study as far as I can see was in no way suggesting that
a dose of vitamin d in the 200 to 400 range was better than one in
the 1200- 2000 range a range more in line with current thinking on
this.Hers the abstract
Vitamin D Supplementation and Total Mortality
A Meta-analysis of Randomized Controlled Trials
Philippe Autier, MD; Sara Gandini, PhD
Arch Intern Med. 2007;167:1730-1737.
Background Ecological and observational studies suggest that low
vitamin D status could be associated with higher mortality from life-
threatening conditions including cancer, cardiovascular disease, and
diabetes mellitus that account for 60% to 70% of total mortality in
high-income countries. We examined the risk of dying from any cause in
subjects who participated in randomized trials testing the impact of
vitamin D supplementation (ergocalciferol [vitamin D2] or
cholecalciferol [vitamin D3]) on any health condition.
Methods The literature up to November 2006 was searched without
language restriction using the following databases: PubMed, ISI Web of
Science (Science Citation Index Expanded), EMBASE, and the Cochrane
Library.
Results We identified 18 independent randomized controlled trials,
including 57 311 participants. A total of 4777 deaths from any cause
occurred during a trial size-adjusted mean of 5.7 years. Daily doses
of vitamin D supplements varied from 300 to 2000 IU. The trial size-
adjusted mean daily vitamin D dose was 528 IU. In 9 trials, there was
a 1.4- to 5.2-fold difference in serum 25-hydroxyvitamin D between the
intervention and control groups. The summary relative risk for
mortality from any cause was 0.93 (95% confidence interval,
0.87-0.99). There was neither indication for heterogeneity nor
indication for publication biases. The summary relative risk did not
change according to the addition of calcium supplements in the
intervention.
Conclusions Intake of ordinary doses of vitamin D supplements seems
to be associated with decreases in total mortality rates. The
relationship between baseline vitamin D status, dose of vitamin D
supplements, and total mortality rates remains to be investigated.
Population-based, placebo-controlled randomized trials with total
mortality as the main end point should be organized for confirming
these findings. '
Thanks Vince
@there Vernono O
<trigonom...@gmail.com> wrote in message
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SORELY, with no doubt.