In article <6pvmrl$i7...@nntp1.ba.best.com>, b...@promind.com (Bob
Wallace) wrote:
}People do get some muscle twitches, and I have heard rumors of real
}convulsions, but don't know if this is common, or a problem.
Tremors and convulsions are a common side-effect reported in the two
major collections of anti-GHB case studies, Chin&Kreutzer (Western Journal
of Medicine, 1992 156: 380-384) and Galloway, et al. (Addiction, 1997
92(1): 89-96), but they seem absent from the popular folklore. Of course,
this may be a selection bias: Those who get tremors don't tend to remain
in the GHB "loop" long enough to share their stories. If they are a
reliable effect, they're probably confined to high doses.
O. Snead Carter has done extensive research into the ability of GHB to
induce seizures in monkeys (Neurology, 1978 28:640). The threshold dose
he reports is 100-200mg/kg I.V., which (when accounting for the heightened
potency of GHB when administered this way) would be ~10-12g P.O. (orally)
in a human. Since the cases in the foregoing articles usually dealt with
regular users who on one occassion took a drastically increased dose, it
isn't incomprehensible that this could be the same mechanism, but in most
I doubt it. One of the higher doses was 150mg/kg orally, which would
probably not equal either the intensity or the speed of 100mg/kg I.V.
In any case, the twitches and tremors in question are minor and
passing. I wouldn't worry about it. Chin and Kreutzer report one case of a
woman whom "a witness stated was. . . banging her head on a wall before
becoming unconscious" as well as suffering seizure and "uncontrollable
shaking," but (even if we are to take their report completely at its word)
she had also been drinking. As is typical with these cases, no one was
able to reliably report how much GHB she had taken or how many drinks
she'd had. As is NOT typical, though, she was given leukocyte, hemoglobin,
hematocrit, thrombocyte, sodium, potassium, bicarbonate, chloride,
creatinine, nitrogen, arterial blood gas decontamination, and blood
pressure counts, and radiographic electroencephalographic, computed
tomographic, and magnetic resonance imaging scans. Somewhere in there they
did manage to get a BAC, which came to 80mg/dl, which is hardly abusive
but indicates several drinks. If you're mixing GHB and alcohol, I say
you're lucky if you get nothing worse than seizures. . .
Michael Cohn
^^^^^^^^^^^^^^^^^^^^^^
So it's under construction. And it's a bit funny looking.
It's still the best-researched and organized GHB FAQ I've ever seen.
http://uts.cc.utexas.edu/~laborit
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