Minoxidil Tolerance

[User132384]

What the heck is meant by the statement

"Rogaine loses its effectiveness in 1 or 2 years?".

John

[CCoach]

What is up with that ? They say its a lifetime committment and now
everyone in this newsgroups says it stops working after a few years or so.
If it's a lifetime committment then one would think it would work for a
lifetime huh ?

[Peter H. Proctor]

In article <4uodp7$q...@newsbf02.news.aol.com> cco...@aol.com (CCoach) writes:
>From: cco...@aol.com (CCoach)
>Subject: Re: Minoxidil Tolerance
>Date: 12 Aug 1996 19:12:39 -0400

In most people, minoxidil keeps working indefinitly , at least as far as
we've got information (roughtly 10-15 years ). About a third of the time,
it stops working by 2-5 years or so. Again, this seems to be more
progression of the balding process rather than drug tolerance per se. In
common with a lot of other types of drug tolerance, minoxidil tolerance can
be mostly prevented by using (e.g. ) another drug such as an antiandrogen
along with minoxidil.

Peter H. Proctor, PhD, MD
(713) 960-1616

[Alan Waterman]

People don't become tolerant to minoxidil. What is probably happening is
that when one starts using it, it stimulates hair thickening and some
hair growth in follicles that are already damaged to some degree by DHT.
What the minox is doing is helping follicles that are border line on
being able to produce hair produce more hair or hair period where the
follicle without the minox is just beyond that threshold of being able
to make it all by itself.

So you continue to use minox and after 4 years or so in some people,
those follicles that were helped by minox stop growing hair. Not because
they have become tolerant to the drug, but because damage to the
follicles still continues from DHT, so eventually, those follicles are
too damaged to produce hair even with help from minox.

This would give the appearance that people become tolerant to minox.

-Alan

[lile...@gmail.com]

Sad, but true. I have a moderate case of alopecia Areata: I began using minoxidil 2% in 2008 when I began to develop bald patches in the back of my hair; this treatment stopped the balding process, but it was not until I began to use 5% that I experienced significant hair regrowth. I was so satisfied with the results I recommended Minoxidil to anyone who listened. However, In 2015, I noticed that the hair on my head had not only stopped responding to the minoxidil, but the resulting hair loss was worst than when I first began. I thought Minoxidil was my life-time cure - and had to find sites like this to inform me that I had developed a tolerance for it. At the end, all it did was drastically increase my facial and arm hair, only... not necessarily desirable results for a woman.

[KWills Shill #3]

Replying to a post 21 years after it was sent? This may be a new
record for the group.
BTW, it's normal to develop a tolerance to medication when used
over long periods of time. Like a year or more.

--
You need only two tools: WD-40 and duct tape.
If it doesn't move and it should, use WD-40.
If it moves and shouldn't, use the duct tape.

[Ernie}]

[%]

so do you but sooner