Clin Nucl Med. 2009 Sep

Luongo JA, Scalcione LR, Katz DS, Yung EY.
Department of Radiology, Winthrop-University Hospital, Mineola, NY
11501, USA.

Lymphedema is due to dysfunction in lymphatic transport, and is
divided into primary and secondary subtypes. Primary lymphedema is a
congenital lymphatic abnormality or dysfunction whereas secondary
lymphedema is characterized by pathologic disruption or obstruction of
a previously-normal lymphatic system. The stage of lymphedema is
determined clinically. Lymphoscintigraphy, however, may be used to
assess disease extent, for early detection of disease progression, and
can be used to direct therapy. We report a case of a 56-year-old woman
with clinically stable lymphedema of 5 years, yet with
lymphoscintigraphy findings compatible with disease progression.

http://www.ncbi.nlm.nih.gov/pubmed/19692818?ordinalpos=26&itool=Entre...