Google always responds to DMCA notifications in my experience. I think the DMCA gives them two weeks, however, and they usually cut it pretty close.
My beef with Google is how they share the notifications with Chilling Effects. Chilling Effects puts up any and all notifications, no matter how legitimate, but then they primarily publicize their project as proof that the DMCA is being abused with illegitimate notifications that have nothing to do with copyright or the DMCA. This has the effect of tarring everyone who appears in their database as a bully.
What's more, they host their site in France, the legal organization of the "clearinghouse" is unspecified, and beyond the top person it's unclear who is involved and what their roles are. This is not the way that reputable organizations operate.
A quick scan of their database shows characteristic OCR spelling errors, so I recommend submitting DMCA notifications in a font like Zapfino. Make them work a little (and make Google's DMCA office squint a little in processing the notifications as payback for their cooperation with Chilling Effects).
"If the domain carry's advertising don't forget to ask the advertiser or ad supplier to refund there revenue to you." Good luck on this one. The DMCA doesn't address this issue, and it's the infringer, not the ad network, who would be liable for damages.