Super Malaria parasites 'resist drugs'
Pastor Dale Morgan
*Super Malaria parasites 'resist drugs'*
Half the world's population is exposed to malaria
BBC - International scientists say they have found the first evidence of
resistance to the world's most effective drug for treating malaria.
They say the trend in western Cambodia has to be urgently contained
because full-blown resistance would be a global health catastrophe.
Drugs are taking longer to clear blood of malaria parasites than before.
This is an early warning sign of emerging resistance to a disease which
kills a million people every year.
Until now the most effective drug cleared all malaria parasites from the
blood within two or three days but in recent trials this took up to four
or five days.
The BBC's Jill McGivering, reporting from Cambodia, says it is unclear
why the region has become a nursery for the resistance - but the local
public health system is weak, and the use of anti-malaria drugs is not
properly controlled.
Drug defence
The artemesinin family of drugs is the world's front-line defence
against the most prevalent and deadly form of malaria.
Chhem Bunchhin, the patient with malaria.
Drug resistance in Cambodia
Two teams of scientists, working on separate clinical trials, have
reported seeing the disturbing evidence that the drugs are becoming much
less effective.
There is particular concern because previous generations of malaria
drugs have been undermined by resistance which started in this way, in
this part of the world, our correspondent reports.
Professor Nick Day is the director of the Mahidol-Oxford Tropical
Medicine Research Unit, one of the teams involved in the research.
"Twice in the past, South East Asia has made a gift, unwittingly, of
drug resistant parasites to the rest of the world, in particular to
Africa," he said.
"That's the problem. We've had chloroquine and SP resistance, both of
which have caused major loss of life in Africa," in said in reference to
earlier generation anti-malarial drugs.
"If the same thing happens again, the spread of a resistant parasite
from Asia to Africa, that will have devastating consequences for malaria
control," he said.
Health systems
Cambodia has long been a laboratory for malaria investigators and a
nursery of anti-malaria drug resistance.
Cinchona bark drying in Dutch East Indies, to be pulverized to make
quinine, 1960s
The fight against malaria has lasted generations
Alongside a weak public health system and poorly-controlled drug use,
there are many fake drugs, produced by international criminals.
These fakes often contain a small amount of the real drug to fool tests,
which can also help to fuel resistance.
Those working to control malaria are calling for urgent action to
contain this emerging resistance.
If it strengthens and spreads, they warn, many millions of lives will be
at risk. About half the world's population faces exposure to the disease.