Sequani Limited

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Sep 29, 2004, 3:01:38 PM9/29/04
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Sequani Limited
Bromyard road
Ledbury
Herefordshire
HR8 1LH

Sequani Limited are a Contract Research Organisation (CRO) previously
named Toxicol Laboratories England and Quintiles UK and have been in
existance in Ledbury since the early 1970s.

Sequani Limited practice acute toxicity tests, reproduction toxicology
tests, carcinogenicity tests and repeat dose toxicology tests on live animals.
The animal test subjects include beagle dogs, rabbits, genetically
stunted pigs known as 'minipigs', transgenic mice, rats and guinea pigs.
Below are detailed descriptions of the tests that this company performs.

Acute Toxicity Tests: Acute toxicity studies in mammals are conducted to
measure a chemical’s capacity to cause harm or death with a single dose.
Chemicals are administered to animals in extremely high doses via at
least two of the following routes:

• Oral –– chemicals are pumped directly into the animal’s stomach via a
force-feeding tube or syringe.
• Skin –– chemicals are painted onto the shaved and abraded skin on the
animal’s back.
• Inhalation –– animals are either confined in an inhalation chamber or
restrained with a breathing apparatus fixed over their mouths.

Acute toxicity studies inflict hideous suffering on animals, who may
endure severe abdominal pain; diarrhea; bleeding from the nose, mouth
and genitals; convulsions; seizures and paralysis before they are
poisoned to death or killed by the experimenter.

Reproduction Toxicology: Reproductive toxicity studies in mammals are
conducted to measure a chemical’s effects on reproductive organs and
fertility. Such tests are based on a repeated dose toxicity study in
rodents, during which animals are examined for changes in sexual
behaviour, sperm and egg production and fertilisation, development in
the uterus and after birth, and hormonal activity. At the conclusion of
the study the animal’s genitals and reproductive organs are often
removed for further study. Animals in reproductive toxicity studies
suffer not only from the toxic effects of the chemical under
investigation, but also as a result of frequent and often stressful
handling, restraint and inhumane force-feeding practices.

Carcinogenicity tests: Carcinogenicity studies are conducted to measure
a chemical’s cancer-causing potential following lifelong exposure.
Carcinogenicity studies call for the use of both rats and mice and can
kill more than 800 animals per test. Animals in these studies are
exposed to toxic chemicals for their entire lives through their food,
their skin or the air they breathe. Carcinogenicity studies can go on
for up to five years, during which animals can endure extended suffering
from chemical- poisoning as their bodies are overcome by tumours and
cancerous growths.

Repeat dose Toxicology: Repeated dose toxicity studies expose animals to
repeated low doses of chemicals for one to three months to measure the
effects of multiple chemical exposures on organs such as the liver,
kidneys, lungs, heart and nervous system. Chemicals are usually
force-fed to animals orally, although skin and inhalation routes are
also used. These studies are typically conducted using two different
species of animal, one rodent (rat, mouse, etc.) and one nonrodent
(usually dogs). Repeated dose studies are highly stressful and cruel, as
animals are subjected to frequent handling, restraint and inhumane
force-feeding practices, in addition to suffering the toxic effects of
the chemical under investigation. The animals can suffer excessive
salivation, anaemia, muscle weakness, hair loss, internal organ damage,
pilo-erection (hair standing on end), vomiting (in dogs), diarrhoea,
coma and even death.



Anti-vivisection protests have been held at this laboratory for over 20
years. The current campaign against Sequani limited focuses not only on
the lab itself but also on the companies that provide services to the
lab.

If you are interested in campaigning against Sequani laboratories, be it
leafletting and helping to inform the public, writing letters, holding
stalls and fundraising, attending the protests outside the lab or
joining the protests at the premises of companies that supply the lab,
please get in touch.

For more information on the campaign against Sequani limited please
email 
worceste...@airpost.net

*Worcestershire Animal Info has taken over from the now Defunct People
Against Cruelty to Animals - West Midlands website. The former name of
that group and its website, have now been dropped for security reasons.
Sequani limited had no hand in the deletion of the PACA website or the
deletion of the umbrella name for campaigners 'PACA - West Midlands'.
Details of supplier companies to Sequani are constantly updated and
freely available on request from the WAI email address and elsewhere on
the internet. The campaign against Sequani limited will never be over
until Sequani stop animal testing altogether, or are closed down
altogether*

WAI:
http://www.vivisection.info/paca (web address will change soon)

Couriers, haulage firms, builders, plumbers, electricians, vehicle
rental firms, cleaners, gas, chemical and lab equipment suppliers,
anyone that does business with Sequani ltd, all play their part in
strengthening the backbone of this death factory.

It's up to all of us who care about the animals that are suffering and
dying in unnecessary, unscientific experiments at Sequani labs to help
persuade these companies to cut their business ties with animal cruelty
by stopping doing business with Sequani ltd.

If you would like to play a part in the campaign against Sequani animal
testing labs but can't make the demos, please write to, email or phone
the companies listed on this page and ask them (politely) to consider
withdrawing their business association with Sequani Ltd on ethical,
moral and compassionate grounds.

AJ Lowther and Son (Building contractors)
Overross Garage
28 Overross Street
Ross On Wye
Herefordshire
HR9 7AS
Tel: 01989 563666
Fax: 01600 890930
Email: 
in...@ajlowther.co.uk

Registered Office: (same as above)

MYG Industrial Services (Animal cage/prison manufacturers)
Barrs Court Industrial Estate
Station Approach
Hereford
Herefordshire
HR1 1BB
Tel: 01432 278102
Fax: 01432 352568

Registered Office:

2 Blackfriars st
Hereford
Herefordshire
HR4 9HS
Tel: 01432 278102

Owen Pell Limited (Building and maintenance contractors)
Twyford Road
Rotherwas Industrial Estate
Hereford
HR2 6JR
Tel: 01432 353441

Registered Office: (same as above)

Steven C Large (Landscape gardener)
1/19 The Homend
Ledbury
HR8 1BN
Tel: 01531 632413

Johnsons Apparelmaster (Workwear rental)
Aldridge Road
Perry Barr
Birmingham
B42 2EU
Tel: 0121 356 4512
Fax: 0121 344 3520
Email: 
graham...@johnsonplc.com

Registered Office:
Mildmay rd
Bootle
Merseyside
L20 5EW
Tel: 0151 933 6161

Scientific Lab Supplies
Orchard House
The Square
Hessle
East Yorkshire
HU13 0AE
Tel: 01482 649665
Fax: 01482 649667
Website:
www.scientific-labs.com
Emails:  ibur...@scientific-labs.commshe...@scientific-labs.com,
ibec...@scientific-labs.comsren...@scientific-labs.com,
mm...@scientific-labs.comtwh...@scientific-labs.com,
cmar...@scientific-labs.combpea...@scientific-labs.com

Registered Office: (same as above)

Lab 3 - Total Laboratory Services
1 Dragon Court
Crofts End Road
Bristol
BS5 7XX
Website:
www.lab3.co.uk

Registered Office: (same as above)

Alex Quinn (Central heating installation and servicing)
2 Churchill Close
Hereford
HR1 1DH
Tel: 01432 270016

ADT Security (Security systems)
Mucklow Hill
Birmingham
B62 8DA
Tel: 0121-255 6000
Fax: 0121-255 6100
Email: 
sales....@tycoint.com

Registered Office:

Security House
The Summit
Hanworth Rd
Sunbury on Thames
Middlesex
TW16 5DB
Tel: 01932 743333

Fisher Scientific
Bishop Meadow Road
Loughborough
Leicestershire
LE11 5RG
Tel: 01509 231166
Fax: 01509 231893
Emails: 
in...@fisher.co.uksa...@fisher.co.uk

Registered Office: (same as above)

Sigma Aldrich Chemicals
The Old Brickyard
New Road
Gillingham
Dorset
SP8 4XT
Tel: 01747 833 000
Fax: 01747 833 154
Emails: 
mbri...@europe.sial.comukcu...@europe.sial.com,
ukor...@eurnotes.sial.com

Registered Office: (same as above)

DHL International Ltd (courier service)
Unit 31
Alexandra Way
Ashchurch Business Centre
Tewkesbury
GL20 8NB
Tel:0870 3661210

Registered Office:

178-188 Great South West Road
Hounslow
Middlesex
TW4 6JS
Tel: 08701 100 300
Email: 
cfo...@dhl.com
Email:  web...@dhl.com

PDP Courier Services
Unit 10, Ashford Industrial Estate,
Shield Road,
Ashford,
Middlesex,
TW15 1AU.
Tel: 01784 420466
Fax: 01784 245519
Email: 
pa...@pdpcouriers.com

Registered Office:

The Old School
51 Princes rd
Weybridge
Surrey
KT13 9DA

TNT Worcester Depot
Unit 134
Hartlebury Trading Estate
Hartlebury
Kidderminster
Worcestershire
DY10 4JB
Tel: 01299 250100
Fax: 01299 250188
Email: 
press...@tnt.co.uk

United Parcel Service
Forest Road
Feltham
Middlesex
TW13 7DY
United Kingdom
Tel: 08457-877-877
E-mail: 
callc...@europe.ups.com
Press and Media Relations: Sarah Bell:  market...@europe.ups.com

Registered Office: (same as above)

Tuffnells Parcel Express
Fenspool Avenue
Wallows Industrial Estate
Dudley Road
Brierley Hill
West Midlands
DY5 1QA
Tel: 01384 263662
Fax: 01384 70427
Email: 
amanda....@tuffnells.co.uk

Registered Office:

Shepcote lane
Sheffield
S9 1UW
Tel: 0114-256 1111

Freightroute Ltd
Unit 10-11 Mill Place
90 Bristol Road
Gloucester
Gloucestershire
GL1 5SQ
Tel: 01452 310301

Registered Office:

Chowns Mill Business Park
Station rd
Irthlingborough
Northants
NN9 5QQ
Tel: 01933 651 521

Global Ice Limited
Unit 41, Halifax Road
The Metropolitan Centre
Greenford
Middlesex
UB6 8XU
England
Tel UK: 020 8575 7112
Tel Worldwide: +44 (0)20 8575 7112
Fax: +44 (0)20 8566 6342
Email: 
enqu...@global-ice.co.uk

Registered Office: (same as above)

Rainbow Nightfreight
Arthur Drive
Hoo farm industrial estate
Kidderminster
Worcester
DY11 7RA
TEL: 01562 68110
FAX: 01562 66579

EMAIL: 
dep...@nightfreight.co.uk

Registered Office:

The Burgage Green
Southwell
Nottinghamshire
NG25 0EP

Business Post
Unit 7
The Park
Spring lane south
Malvern
Worcestershire
WR14 1AT
TEL: 01684 891844

Business Post Midlands Head Office
Birmingham National Hub
Express House
Wolseley Drive
Heartlands
Birmingham
B8 2SQ
TEL: 0121 335 1040

Registered Office:

Express House
464 Berkshire Avenue
Slough
Berkshire
SL1 4PL
Tel: 01753 814333


INFORMATION AS A WEAPON:

Because of the highly paranoid and secretive nature of Sequani Ltd,
other companies that are involved with them may not be fully aware of
what goes on behind Sequanis closed doors ... It's time to LET THEM
KNOW! Five companies that have severed their ties with Sequani said they
didn't have a clue what went on there!

Remember that every email sent, every letter written and every phone
call made to these companies is in itself an extremely effective way to
protest!

TAKING PRECAUTIONS:

Use the prefix 141 before ringing these companies if you want your
anonymity kept intact, better still, use a public phone box and the
prefix. More than two emails can be classed as harassment (depending on
what you say in the mail) try and use different email accounts or you
could use a computer in a public library.

THEIR ONLY HOPE, YOU!:

You are the laboratory animals last and only hope. They sit in cages and
pens waiting for that terrifying moment when the vivisectors come for
them to poison them and tear them apart. We cannot fail them. If you
care about the animals please get on to these companies right away.

We can safely forget about government and authority lending a helping
hand to aid those that are suffering and dying at the hands of big
business.

Only together, can we stop or at least slow the murder rate down at
Sequani limited and every other animal torturing centre and make life
very uncomfortable and costworthy for the animal abusers. Please, Just
Do It.


For more info on the pointlessness of animal vivisection please visit:

Americans, Europeans, Japanese for Medical Advancement:
http://www.curedisease.com

The Absurdity of Vivisection: http://www.vivisection-absurd.org.uk

Doctor Hadwen Trust: http://www.drhadwentrust.org.uk

Doctors and Lawyers for Responsible Medicine: http://www.dlrm.org


Thanks for your time.

Worcestershire Animal Info:
http://www.vivisection.info/paca

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